ENSG00000118961

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000237822 ENSG00000118961 No_inf pgKDN_inf LDAH protein_coding protein_coding 12.23399 9.047403 15.68558 0.4121652 0.6909211 0.7931894 5.9998080 4.2304554 7.804557 1.5457777 0.1911916 0.8819449 0.51676667 0.482500 0.499450 0.016950 1.000000e+00 2.976094e-06 FALSE TRUE
ENST00000402479 ENSG00000118961 No_inf pgKDN_inf LDAH protein_coding protein_coding 12.23399 9.047403 15.68558 0.4121652 0.6909211 0.7931894 0.2720423 0.8161268 0.000000 0.5146797 0.0000000 -6.3682914 0.02788333 0.083650 0.000000 -0.083650 3.845814e-01 2.976094e-06 FALSE FALSE
ENST00000440866 ENSG00000118961 No_inf pgKDN_inf LDAH protein_coding protein_coding 12.23399 9.047403 15.68558 0.4121652 0.6909211 0.7931894 0.6241495 0.8702669 1.002182 0.5914579 1.0021817 0.2014554 0.05255833 0.088850 0.068825 -0.020025 8.084499e-01 2.976094e-06 TRUE TRUE
ENST00000541941 ENSG00000118961 No_inf pgKDN_inf LDAH protein_coding protein_coding 12.23399 9.047403 15.68558 0.4121652 0.6909211 0.7931894 1.7742747 2.2834832 1.531899 1.3230736 0.9051607 -0.5728317 0.15043333 0.243275 0.100475 -0.142800 9.130305e-01 2.976094e-06 FALSE TRUE
ENST00000626491 ENSG00000118961 No_inf pgKDN_inf LDAH protein_coding protein_coding 12.23399 9.047403 15.68558 0.4121652 0.6909211 0.7931894 1.8369971 0.0000000 4.040837 0.0000000 0.4661231 8.6620763 0.12585833 0.000000 0.256075 0.256075 2.976094e-06 2.976094e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000118961 E001 0.1176306 0.0117613300 0.780872108   2 20684014 20684027 14 - 0.080 0.000 -9.756
ENSG00000118961 E002 0.1176306 0.0117613300 0.780872108   2 20684028 20684030 3 - 0.080 0.000 -12.131
ENSG00000118961 E003 0.1176306 0.0117613300 0.780872108   2 20684031 20684031 1 - 0.080 0.000 -12.131
ENSG00000118961 E004 0.2448930 0.0165100835 0.775113562   2 20684032 20684036 5 - 0.080 0.112 0.537
ENSG00000118961 E005 0.3717469 0.0167262532 0.380811820   2 20684037 20684043 7 - 0.080 0.201 1.537
ENSG00000118961 E006 0.7618760 0.0134090115 0.002543469 0.03050400 2 20684044 20684115 72 - 0.000 0.442 14.324
ENSG00000118961 E007 8.8799116 0.0016933329 0.001302896 0.01836175 2 20684116 20684411 296 - 0.838 1.136 1.106
ENSG00000118961 E008 16.5944143 0.0050123545 0.294273481 0.58758868 2 20684412 20684875 464 - 1.205 1.285 0.282
ENSG00000118961 E009 3.5176499 0.0043485736 0.742583352 0.89832747 2 20684876 20684923 48 - 0.668 0.628 -0.173
ENSG00000118961 E010 37.0052865 0.0009018412 0.051287786 0.22434351 2 20684924 20685546 623 - 1.533 1.626 0.318
ENSG00000118961 E011 10.7706407 0.0013479570 0.130853693 0.38370375 2 20685547 20685657 111 - 1.006 1.136 0.472
ENSG00000118961 E012 61.7311900 0.0002557301 0.446177973 0.72060843 2 20685658 20686624 967 - 1.780 1.809 0.096
ENSG00000118961 E013 13.6443088 0.0612657572 0.866818652 0.95412430 2 20686625 20686837 213 - 1.146 1.180 0.121
ENSG00000118961 E014 7.1858925 0.0020514563 0.822352135 0.93557116 2 20686838 20686906 69 - 0.898 0.923 0.094
ENSG00000118961 E015 21.7798272 0.0006952722 0.045163654 0.20779393 2 20686907 20687094 188 - 1.401 1.278 -0.427
ENSG00000118961 E016 8.1874927 0.0406654344 0.047130589 0.21328651 2 20701570 20701574 5 - 1.048 0.800 -0.937
ENSG00000118961 E017 11.9138122 0.0029655006 0.002501203 0.03011159 2 20701575 20701652 78 - 1.200 0.938 -0.952
ENSG00000118961 E018 7.9947214 0.0022136433 0.448676433 0.72263609 2 20739971 20740051 81 - 0.979 0.907 -0.270
ENSG00000118961 E019 10.8422765 0.0015557819 0.734728374 0.89474481 2 20740052 20740205 154 - 1.055 1.087 0.113
ENSG00000118961 E020 5.3341710 0.0028083916 0.535270543 0.78507841 2 20774810 20774857 48 - 0.825 0.757 -0.270
ENSG00000118961 E021 9.6813186 0.0013971387 0.183075930 0.45972703 2 20774858 20774979 122 - 1.071 0.952 -0.436
ENSG00000118961 E022 0.1272623 0.0124895855 0.368598245   2 20788889 20789340 452 - 0.000 0.112 11.984
ENSG00000118961 E023 10.0460496 0.0013830706 0.174195432 0.44783147 2 20790255 20790398 144 - 1.085 0.966 -0.437
ENSG00000118961 E024 0.3801504 0.0264696347 0.050725461   2 20801292 20801309 18 - 0.000 0.275 13.403
ENSG00000118961 E025 7.0270926 0.0214538172 0.364742072 0.65329433 2 20801310 20801465 156 - 0.941 0.839 -0.389
ENSG00000118961 E026 2.0508535 0.0844140043 0.414106408 0.69445400 2 20823037 20823130 94 - 0.536 0.393 -0.726

Help

Please Click HERE to learn more details about the results from DEXseq.