ENSG00000119048

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265339 ENSG00000119048 No_inf pgKDN_inf UBE2B protein_coding protein_coding 88.8984 109.7333 53.68441 11.32828 18.21632 -1.03129 28.345212 34.912170 28.994193 1.3481940 0.5765086 -0.2678818 0.4257333 0.332825 0.684150 0.351325 0.07376633 0.04477418 FALSE TRUE
ENST00000504431 ENSG00000119048 No_inf pgKDN_inf UBE2B protein_coding retained_intron 88.8984 109.7333 53.68441 11.32828 18.21632 -1.03129 54.376155 69.086731 18.147087 12.1362680 18.1470871 -1.9280847 0.4803917 0.613825 0.167550 -0.446275 0.04477418 0.04477418   FALSE
ENST00000507277 ENSG00000119048 No_inf pgKDN_inf UBE2B protein_coding protein_coding 88.8984 109.7333 53.68441 11.32828 18.21632 -1.03129 3.755905 3.032413 3.985243 0.5038646 0.6685232 0.3930674 0.0564000 0.028400 0.084575 0.056175 0.14443084 0.04477418 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000119048 E001 0.5990472 0.0151885711 0.1117671668 0.351162203 5 134371184 134371468 285 + 0.319 0.087 -2.301
ENSG00000119048 E002 0.2543986 0.0163734507 0.3226890440   5 134371469 134371501 33 + 0.000 0.159 10.698
ENSG00000119048 E003 3.4125704 0.0255385169 0.2300031062 0.518516449 5 134371502 134371568 67 + 0.728 0.562 -0.716
ENSG00000119048 E004 13.1593804 0.0010542764 0.0149324249 0.104746413 5 134371569 134371598 30 + 1.245 1.056 -0.677
ENSG00000119048 E005 16.0367462 0.0008685905 0.0002625731 0.005217987 5 134371599 134371605 7 + 1.357 1.096 -0.922
ENSG00000119048 E006 26.7974086 0.0005513857 0.0563158786 0.236626722 5 134371606 134371639 34 + 1.497 1.391 -0.367
ENSG00000119048 E007 45.1101238 0.0003232112 0.1011769883 0.332209892 5 134374383 134374463 81 + 1.698 1.628 -0.238
ENSG00000119048 E008 0.2542726 0.2423490278 0.3786409146   5 134374464 134374491 28 + 0.000 0.159 9.979
ENSG00000119048 E009 0.3815350 0.0279838689 0.1521056436   5 134374492 134374583 92 + 0.000 0.221 11.169
ENSG00000119048 E010 24.7664250 0.0010672495 0.2269044073 0.515126586 5 134376669 134376673 5 + 1.446 1.375 -0.244
ENSG00000119048 E011 29.7370831 0.0028161933 0.7436869540 0.898622430 5 134376674 134376694 21 + 1.494 1.476 -0.062
ENSG00000119048 E012 64.2979459 0.0002584723 0.1803707137 0.455844234 5 134380719 134380808 90 + 1.782 1.831 0.167
ENSG00000119048 E013 0.8794420 0.0128202008 0.0890308518 0.309593163 5 134385603 134385636 34 + 0.104 0.366 2.284
ENSG00000119048 E014 3.5803688 0.0546191519 0.5167591523 0.772453317 5 134388138 134388324 187 + 0.601 0.696 0.411
ENSG00000119048 E015 38.1135786 0.0009609113 0.8484634713 0.946336109 5 134388325 134388351 27 + 1.582 1.593 0.036
ENSG00000119048 E016 52.6378806 0.0004154597 0.6523304645 0.853495494 5 134388352 134388413 62 + 1.714 1.734 0.065
ENSG00000119048 E017 1.2184628 0.1626832591 0.4651344481 0.734348639 5 134388977 134389052 76 + 0.420 0.275 -0.886
ENSG00000119048 E018 2.9094327 0.0051466655 0.0849237492 0.301234955 5 134389866 134390224 359 + 0.705 0.475 -1.038
ENSG00000119048 E019 305.1187726 0.0001006284 0.0015759164 0.021243558 5 134390225 134392108 1884 + 2.458 2.499 0.138

Help

Please Click HERE to learn more details about the results from DEXseq.