ENSG00000119185

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000460720 ENSG00000119185 No_inf pgKDN_inf ITGB1BP1 protein_coding retained_intron 100.4758 99.76258 106.3146 3.058846 3.521653 0.09176056 4.553744 8.000951 2.231507 2.784003 1.1779121 -1.837504765 0.04505833 0.078225 0.020675 -0.057550 4.437749e-01 1.446572e-08 FALSE  
ENST00000464228 ENSG00000119185 No_inf pgKDN_inf ITGB1BP1 protein_coding nonsense_mediated_decay 100.4758 99.76258 106.3146 3.058846 3.521653 0.09176056 23.441674 14.754851 25.685381 6.480148 5.7368726 0.799342184 0.23469167 0.153550 0.238025 0.084475 7.769402e-01 1.446572e-08    
ENST00000488451 ENSG00000119185 No_inf pgKDN_inf ITGB1BP1 protein_coding protein_coding 100.4758 99.76258 106.3146 3.058846 3.521653 0.09176056 5.712696 3.496902 9.514173 2.083335 4.1866706 1.441396627 0.05473333 0.035725 0.086300 0.050575 7.580299e-01 1.446572e-08 FALSE  
ENST00000492079 ENSG00000119185 No_inf pgKDN_inf ITGB1BP1 protein_coding protein_coding 100.4758 99.76258 106.3146 3.058846 3.521653 0.09176056 6.100864 8.507998 6.273359 1.004439 0.8818490 -0.438978409 0.06034167 0.085000 0.059050 -0.025950 7.312391e-01 1.446572e-08 FALSE  
ENST00000497031 ENSG00000119185 No_inf pgKDN_inf ITGB1BP1 protein_coding protein_coding_CDS_not_defined 100.4758 99.76258 106.3146 3.058846 3.521653 0.09176056 5.438467 6.543711 7.010480 2.325019 2.7413992 0.099257747 0.05398333 0.064600 0.068125 0.003525 1.000000e+00 1.446572e-08 FALSE  
MSTRG.15838.10 ENSG00000119185 No_inf pgKDN_inf ITGB1BP1 protein_coding   100.4758 99.76258 106.3146 3.058846 3.521653 0.09176056 2.030246 0.000000 6.090737 0.000000 0.9595604 9.252839658 0.01938333 0.000000 0.058150 0.058150 1.446572e-08 1.446572e-08 TRUE  
MSTRG.15838.14 ENSG00000119185 No_inf pgKDN_inf ITGB1BP1 protein_coding   100.4758 99.76258 106.3146 3.058846 3.521653 0.09176056 22.875074 26.199722 22.136889 3.882726 8.1799742 -0.242997987 0.22891667 0.260325 0.211525 -0.048800 8.822374e-01 1.446572e-08 TRUE  
MSTRG.15838.21 ENSG00000119185 No_inf pgKDN_inf ITGB1BP1 protein_coding   100.4758 99.76258 106.3146 3.058846 3.521653 0.09176056 10.800676 11.032267 10.967012 1.352651 4.8924504 -0.008550912 0.10812500 0.112025 0.102950 -0.009075 8.497938e-01 1.446572e-08 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000119185 E001 0.0000000       2 9403475 9405683 2209 -      
ENSG00000119185 E002 0.0000000       2 9405684 9405693 10 -      
ENSG00000119185 E003 0.5073513 0.0159207046 0.047682787 0.21474365 2 9405694 9405878 185 - 0.000 0.294 11.225
ENSG00000119185 E004 1.3783900 0.0299796265 0.037617683 0.18702730 2 9405879 9406021 143 - 0.175 0.502 2.138
ENSG00000119185 E005 0.3729758 0.1909368926 0.641103803   2 9406022 9406060 39 - 0.096 0.172 0.968
ENSG00000119185 E006 0.3729758 0.1909368926 0.641103803   2 9406061 9406106 46 - 0.096 0.172 0.968
ENSG00000119185 E007 0.0000000       2 9406107 9406158 52 -      
ENSG00000119185 E008 0.0000000       2 9406159 9406214 56 -      
ENSG00000119185 E009 0.0000000       2 9406215 9406326 112 -      
ENSG00000119185 E010 0.0000000       2 9406327 9406348 22 -      
ENSG00000119185 E011 0.0000000       2 9406349 9406438 90 -      
ENSG00000119185 E012 0.0000000       2 9406439 9406494 56 -      
ENSG00000119185 E013 1.2267695 0.0610779545 0.969410432 0.99369360 2 9406495 9406647 153 - 0.350 0.344 -0.032
ENSG00000119185 E014 1.0981527 0.0112411700 0.714266693 0.88490053 2 9406648 9406659 12 - 0.350 0.294 -0.354
ENSG00000119185 E015 1.9628034 0.0160218090 0.961492705 0.99159586 2 9406660 9406660 1 - 0.474 0.468 -0.032
ENSG00000119185 E016 2.3155145 0.0072150442 0.464490858 0.73397930 2 9406661 9406666 6 - 0.571 0.468 -0.491
ENSG00000119185 E017 7.6430980 0.0054394453 0.030085946 0.16319575 2 9406667 9406685 19 - 1.037 0.817 -0.830
ENSG00000119185 E018 44.7937275 0.0003432850 0.061770626 0.24974040 2 9406686 9406813 128 - 1.701 1.620 -0.276
ENSG00000119185 E019 59.6594785 0.0002797861 0.955278183 0.98915226 2 9406814 9406905 92 - 1.781 1.784 0.010
ENSG00000119185 E020 3.3395587 0.0046912137 0.201636687 0.48401608 2 9406906 9407029 124 - 0.541 0.709 0.734
ENSG00000119185 E021 9.8803133 0.0013967494 0.057507040 0.23974836 2 9407030 9407448 419 - 0.938 1.109 0.629
ENSG00000119185 E022 74.0466645 0.0002960627 0.114737850 0.35704311 2 9407449 9407542 94 - 1.845 1.900 0.184
ENSG00000119185 E023 46.5200230 0.0003431112 0.336775420 0.62880446 2 9407543 9407571 29 - 1.654 1.696 0.143
ENSG00000119185 E024 31.9068564 0.0011722474 0.432413899 0.70980447 2 9407572 9407584 13 - 1.494 1.537 0.146
ENSG00000119185 E025 27.7048990 0.0006712340 0.826473360 0.93716084 2 9407585 9407598 14 - 1.451 1.464 0.045
ENSG00000119185 E026 1.8392526 0.0759157078 0.843201588 0.94392234 2 9408002 9408112 111 - 0.436 0.468 0.161
ENSG00000119185 E027 50.1094586 0.0003745725 0.915751946 0.97357880 2 9408113 9408151 39 - 1.705 1.711 0.018
ENSG00000119185 E028 53.8033568 0.0003170449 0.260509299 0.55307465 2 9408152 9408201 50 - 1.761 1.717 -0.150
ENSG00000119185 E029 33.4707264 0.0005067710 0.158854049 0.42593260 2 9408202 9408205 4 - 1.573 1.502 -0.243
ENSG00000119185 E030 2.7555884 0.0066340573 0.002662082 0.03152867 2 9408206 9408404 199 - 0.299 0.729 2.138
ENSG00000119185 E031 0.7332355 0.0491007039 0.981060514 0.99804343 2 9412068 9412268 201 - 0.241 0.237 -0.032
ENSG00000119185 E032 46.4563983 0.0004365533 0.244808433 0.53522243 2 9412269 9412296 28 - 1.701 1.651 -0.169
ENSG00000119185 E033 32.8737888 0.0004575593 0.321614158 0.61465528 2 9412297 9412303 7 - 1.555 1.505 -0.171
ENSG00000119185 E034 54.0735289 0.0002811693 0.403237145 0.68623603 2 9412304 9412359 56 - 1.757 1.725 -0.110
ENSG00000119185 E035 52.4235050 0.0008865339 0.880449378 0.95976225 2 9412360 9412405 46 - 1.730 1.725 -0.018
ENSG00000119185 E036 1.0891540 0.0110497362 0.301721026 0.59496990 2 9412406 9412717 312 - 0.395 0.237 -1.032
ENSG00000119185 E037 59.6288167 0.0002582009 0.683660671 0.86905686 2 9414178 9414256 79 - 1.790 1.775 -0.050
ENSG00000119185 E038 58.6484462 0.0004609719 0.688909083 0.87189071 2 9418626 9418732 107 - 1.783 1.768 -0.050
ENSG00000119185 E039 16.0319773 0.0008687486 0.032056127 0.16932953 2 9419990 9420100 111 - 1.142 1.298 0.553
ENSG00000119185 E040 11.3544319 0.0012171719 0.049402399 0.21917972 2 9420101 9420429 329 - 0.996 1.163 0.606
ENSG00000119185 E041 15.4234603 0.0009652372 0.035853621 0.18162198 2 9422479 9422660 182 - 1.126 1.282 0.553
ENSG00000119185 E042 11.2521006 0.0018222586 0.751038823 0.90179419 2 9422661 9422801 141 - 1.101 1.075 -0.095
ENSG00000119185 E043 13.0320259 0.0011564591 0.117739788 0.36249455 2 9422802 9422965 164 - 1.207 1.084 -0.439
ENSG00000119185 E044 7.1981584 0.0098192026 0.486225750 0.74998855 2 9422966 9422989 24 - 0.950 0.877 -0.277
ENSG00000119185 E045 18.2406304 0.0125152524 0.950172996 0.98713033 2 9422990 9423250 261 - 1.286 1.282 -0.012
ENSG00000119185 E046 0.2533610 0.0159837559 0.250676370   2 9423278 9423372 95 - 0.000 0.171 10.230
ENSG00000119185 E047 29.3385175 0.0005325755 0.358528475 0.64808375 2 9423373 9423528 156 - 1.454 1.505 0.174

Help

Please Click HERE to learn more details about the results from DEXseq.