ENSG00000119396

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000703996 ENSG00000119396 No_inf pgKDN_inf RAB14 protein_coding protein_coding 81.49145 73.27991 92.59826 0.5727562 0.9638116 0.3375262 16.57967 24.0557422 16.65565 1.8678347 7.726309 -0.5301036 0.2076333 0.328500 0.178250 -0.150250 0.588731963 0.002964726 FALSE TRUE
ENST00000703997 ENSG00000119396 No_inf pgKDN_inf RAB14 protein_coding nonsense_mediated_decay 81.49145 73.27991 92.59826 0.5727562 0.9638116 0.3375262 28.71914 24.7215330 32.30311 0.3334429 1.618635 0.3857679 0.3527083 0.337475 0.349475 0.012000 0.960586264 0.002964726 FALSE FALSE
ENST00000703998 ENSG00000119396 No_inf pgKDN_inf RAB14 protein_coding protein_coding 81.49145 73.27991 92.59826 0.5727562 0.9638116 0.3375262 20.57708 21.5136164 17.91827 2.1956677 10.644824 -0.2636841 0.2575833 0.293100 0.196650 -0.096450 0.760872418 0.002964726 FALSE TRUE
ENST00000704000 ENSG00000119396 No_inf pgKDN_inf RAB14 protein_coding protein_coding 81.49145 73.27991 92.59826 0.5727562 0.9638116 0.3375262 12.69406 0.7737786 20.98499 0.7737786 5.693355 4.7434551 0.1474833 0.010775 0.225150 0.214375 0.002964726 0.002964726 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000119396 E001 4.7192169 2.951988e-02 1.644027e-02 1.115193e-01 9 121178133 121179304 1172 - 0.573 0.893 1.316
ENSG00000119396 E002 2.3483780 6.256777e-03 1.507736e-01 4.135385e-01 9 121179305 121179311 7 - 0.415 0.618 0.979
ENSG00000119396 E003 3.3186454 1.566790e-02 3.682192e-01 6.567306e-01 9 121179312 121179313 2 - 0.573 0.693 0.523
ENSG00000119396 E004 6.8899429 2.622379e-03 1.173717e-01 3.619190e-01 9 121179314 121179320 7 - 0.811 0.973 0.616
ENSG00000119396 E005 937.3455668 7.751811e-05 7.071173e-07 3.417353e-05 9 121179321 121181498 2178 - 2.959 2.986 0.090
ENSG00000119396 E006 52.1065704 3.296792e-04 7.670457e-02 2.831805e-01 9 121181499 121181573 75 - 1.759 1.686 -0.247
ENSG00000119396 E007 36.8702652 4.368090e-04 6.510522e-04 1.071838e-02 9 121182930 121182960 31 - 1.652 1.483 -0.577
ENSG00000119396 E008 46.1286059 3.384456e-04 1.379031e-03 1.918957e-02 9 121183311 121183382 72 - 1.736 1.595 -0.479
ENSG00000119396 E009 19.9646238 1.649930e-02 4.378741e-01 7.141091e-01 9 121183383 121183398 16 - 1.351 1.287 -0.224
ENSG00000119396 E010 32.3565090 1.183412e-02 2.415123e-01 5.312719e-01 9 121186953 121187019 67 - 1.561 1.479 -0.280
ENSG00000119396 E011 65.9145174 2.340570e-04 6.449787e-01 8.496517e-01 9 121190554 121190731 178 - 1.833 1.817 -0.056
ENSG00000119396 E012 33.5515739 4.453819e-04 5.489107e-01 7.937297e-01 9 121192171 121192224 54 - 1.553 1.522 -0.104
ENSG00000119396 E013 26.7741330 5.232174e-04 1.244076e-01 3.737633e-01 9 121193361 121193419 59 - 1.484 1.396 -0.302
ENSG00000119396 E014 0.1170040 1.172740e-02 6.171400e-01   9 121193420 121193443 24 - 0.089 0.000 -8.144
ENSG00000119396 E015 0.2458395 1.659767e-02 9.142846e-01   9 121200876 121201238 363 - 0.089 0.101 0.201
ENSG00000119396 E016 43.8086220 1.366421e-03 5.886556e-02 2.433026e-01 9 121201639 121201869 231 - 1.692 1.603 -0.301
ENSG00000119396 E017 0.0000000       9 121222200 121222253 54 -      
ENSG00000119396 E018 0.0000000       9 121222910 121223014 105 -      

Help

Please Click HERE to learn more details about the results from DEXseq.