ENSG00000119402

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000453291 ENSG00000119402 No_inf pgKDN_inf FBXW2 protein_coding nonsense_mediated_decay 13.55058 13.71672 13.83574 0.1415843 0.3504749 0.01245541 1.104773 0.000000 1.6505862 0.0000000 0.5867986 7.3755488 0.0807750 0.00000 0.118575 0.118575 0.04744665 0.04744665 TRUE TRUE
MSTRG.29221.6 ENSG00000119402 No_inf pgKDN_inf FBXW2 protein_coding   13.55058 13.71672 13.83574 0.1415843 0.3504749 0.01245541 1.396802 2.752835 0.6148678 0.6966331 0.3551227 -2.1445265 0.1030167 0.19920 0.046225 -0.152975 0.35518124 0.04744665 FALSE TRUE
MSTRG.29221.7 ENSG00000119402 No_inf pgKDN_inf FBXW2 protein_coding   13.55058 13.71672 13.83574 0.1415843 0.3504749 0.01245541 9.693910 9.449325 10.3897307 0.3313803 0.6215766 0.1367371 0.7156083 0.68975 0.749250 0.059500 0.83578623 0.04744665 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000119402 E001 0.7542894 1.419637e-02 1.339955e-01 3.889409e-01 9 120751978 120753059 1082 - 0.102 0.329 2.094
ENSG00000119402 E002 0.0000000       9 120753060 120753114 55 -      
ENSG00000119402 E003 0.0000000       9 120753115 120753311 197 -      
ENSG00000119402 E004 2.5897365 9.252290e-03 7.685313e-01 9.105198e-01 9 120756974 120757719 746 - 0.529 0.570 0.190
ENSG00000119402 E005 4.4278662 3.447967e-03 8.409313e-01 9.429761e-01 9 120757720 120758988 1269 - 0.719 0.743 0.097
ENSG00000119402 E006 1.0067043 1.312892e-02 4.422384e-02 2.056739e-01 9 120758989 120759178 190 - 0.102 0.412 2.583
ENSG00000119402 E007 232.8603290 9.712453e-05 1.116109e-21 3.526869e-19 9 120759179 120762431 3253 - 2.280 2.424 0.483
ENSG00000119402 E008 118.0287966 1.533810e-04 5.174359e-03 5.087020e-02 9 120762432 120764847 2416 - 2.110 2.041 -0.231
ENSG00000119402 E009 23.9960688 6.649050e-04 1.654849e-01 4.352245e-01 9 120771348 120771517 170 - 1.439 1.357 -0.284
ENSG00000119402 E010 16.0215149 8.457315e-04 1.835334e-01 4.603943e-01 9 120772754 120772840 87 - 1.279 1.184 -0.335
ENSG00000119402 E011 21.2288475 7.715812e-04 1.611875e-02 1.102115e-01 9 120776093 120776226 134 - 1.422 1.271 -0.524
ENSG00000119402 E012 3.9613349 3.671050e-03 1.819448e-01 4.579766e-01 9 120776227 120776655 429 - 0.592 0.760 0.708
ENSG00000119402 E013 1.3302505 4.551808e-01 5.370812e-01 7.861571e-01 9 120776931 120777021 91 - 0.455 0.280 -1.029
ENSG00000119402 E014 25.6180534 8.513146e-04 5.640827e-06 2.083783e-04 9 120778351 120778545 195 - 1.549 1.286 -0.907
ENSG00000119402 E015 45.3301707 3.206145e-04 6.658435e-09 4.879294e-07 9 120787769 120788186 418 - 1.784 1.535 -0.845
ENSG00000119402 E016 4.1433419 3.486793e-03 2.599111e-01 5.525442e-01 9 120788187 120788278 92 - 0.780 0.643 -0.566
ENSG00000119402 E017 0.6158571 2.187152e-02 7.846016e-01 9.168588e-01 9 120792887 120793148 262 - 0.184 0.225 0.360
ENSG00000119402 E018 0.0000000       9 120793149 120793257 109 -      
ENSG00000119402 E019 0.0000000       9 120793258 120793353 96 -      
ENSG00000119402 E020 0.0000000       9 120793354 120793359 6 -      
ENSG00000119402 E021 0.0000000       9 120793360 120793417 58 -      

Help

Please Click HERE to learn more details about the results from DEXseq.