ENSG00000119471

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000398803 ENSG00000119471 No_inf pgKDN_inf HSDL2 protein_coding protein_coding 7.284728 6.962716 7.686205 0.2417269 0.07235862 0.1424265 1.603883 2.444626 0.1555592 0.5116067 0.1555592 -3.8900834 0.2265417 0.351950 0.02 -0.331950 0.0115332749 0.0007445516 FALSE TRUE
ENST00000398805 ENSG00000119471 No_inf pgKDN_inf HSDL2 protein_coding protein_coding 7.284728 6.962716 7.686205 0.2417269 0.07235862 0.1424265 5.515727 4.402823 7.5306461 0.4699921 0.1403473 0.7729862 0.7510000 0.631125 0.98 0.348875 0.0007445516 0.0007445516 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000119471 E001 0.888257 0.012325846 0.004642739 0.04695322 9 112380080 112380103 24 + 0.000 0.433 11.806
ENSG00000119471 E002 0.888257 0.012325846 0.004642739 0.04695322 9 112380104 112380107 4 + 0.000 0.433 13.703
ENSG00000119471 E003 1.252735 0.010413047 0.054473287 0.23247051 9 112380108 112380121 14 + 0.173 0.470 1.993
ENSG00000119471 E004 2.940398 0.004962690 0.966636339 0.99328528 9 112380122 112380180 59 + 0.596 0.594 -0.007
ENSG00000119471 E005 6.649679 0.002397162 0.007494801 0.06613622 9 112403995 112404158 164 + 1.003 0.732 -1.047
ENSG00000119471 E006 5.961717 0.101704088 0.315351196 0.60825947 9 112405624 112405722 99 + 0.910 0.769 -0.544
ENSG00000119471 E007 7.066218 0.034901888 0.339693468 0.63136769 9 112408907 112409021 115 + 0.959 0.851 -0.408
ENSG00000119471 E008 0.000000       9 112414002 112414036 35 +      
ENSG00000119471 E009 5.535372 0.006929635 0.500505692 0.76056842 9 112416841 112416944 104 + 0.771 0.851 0.315
ENSG00000119471 E010 2.532149 0.005361000 0.042819864 0.20168077 9 112418860 112418884 25 + 0.670 0.392 -1.329
ENSG00000119471 E011 4.519726 0.003161653 0.584607443 0.81539604 9 112418885 112418958 74 + 0.771 0.712 -0.242
ENSG00000119471 E012 10.174546 0.001353730 0.973625833 0.99528748 9 112438431 112438625 195 + 1.044 1.051 0.027
ENSG00000119471 E013 0.000000       9 112438743 112438812 70 +      
ENSG00000119471 E014 5.543622 0.003038368 0.320275863 0.61310990 9 112441699 112441770 72 + 0.753 0.866 0.445
ENSG00000119471 E015 0.126854 0.012312018 0.546805717   9 112447610 112447646 37 + 0.000 0.095 11.187
ENSG00000119471 E016 8.931610 0.017054037 0.715877848 0.88547399 9 112454013 112454162 150 + 1.014 0.980 -0.127
ENSG00000119471 E017 10.754436 0.034155248 0.696297437 0.87604054 9 112459449 112459577 129 + 1.089 1.051 -0.139
ENSG00000119471 E018 70.557577 0.000310711 0.132512492 0.38640402 9 112470432 112472450 2019 + 1.831 1.875 0.148

Help

Please Click HERE to learn more details about the results from DEXseq.