ENSG00000119487

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265960 ENSG00000119487 No_inf pgKDN_inf MAPKAP1 protein_coding protein_coding 67.75915 52.38773 74.41368 1.825515 8.925537 0.5062576 18.236804 9.699540 21.650404 3.878569 2.089691 1.1575853 0.26772500 0.192200 0.301600 0.109400 0.758775421 0.009614548 FALSE TRUE
ENST00000373498 ENSG00000119487 No_inf pgKDN_inf MAPKAP1 protein_coding protein_coding 67.75915 52.38773 74.41368 1.825515 8.925537 0.5062576 2.953093 7.005761 1.853517 4.060778 1.853517 -1.9125713 0.04880000 0.127475 0.018925 -0.108550 0.833554183 0.009614548 FALSE TRUE
ENST00000373503 ENSG00000119487 No_inf pgKDN_inf MAPKAP1 protein_coding protein_coding 67.75915 52.38773 74.41368 1.825515 8.925537 0.5062576 2.363171 4.921761 1.417531 1.873536 1.046687 -1.7885806 0.04175000 0.094400 0.021425 -0.072975 0.319527723 0.009614548 FALSE TRUE
ENST00000394060 ENSG00000119487 No_inf pgKDN_inf MAPKAP1 protein_coding protein_coding 67.75915 52.38773 74.41368 1.825515 8.925537 0.5062576 6.503022 3.972428 7.994943 1.243987 1.083258 1.0072427 0.09736667 0.073525 0.117500 0.043975 0.804842887 0.009614548 FALSE TRUE
ENST00000420643 ENSG00000119487 No_inf pgKDN_inf MAPKAP1 protein_coding protein_coding 67.75915 52.38773 74.41368 1.825515 8.925537 0.5062576 8.511321 1.966411 11.344723 1.215958 4.172566 2.5223374 0.11224167 0.035800 0.140300 0.104500 0.588862920 0.009614548 FALSE TRUE
ENST00000444226 ENSG00000119487 No_inf pgKDN_inf MAPKAP1 protein_coding protein_coding 67.75915 52.38773 74.41368 1.825515 8.925537 0.5062576 7.753538 0.000000 12.465482 0.000000 4.360199 10.2848798 0.11040833 0.000000 0.186400 0.186400 0.009614548 0.009614548 FALSE FALSE
ENST00000496658 ENSG00000119487 No_inf pgKDN_inf MAPKAP1 protein_coding protein_coding_CDS_not_defined 67.75915 52.38773 74.41368 1.825515 8.925537 0.5062576 14.750240 16.684477 8.702088 1.590039 8.702088 -0.9382805 0.21489167 0.318200 0.088900 -0.229300 0.010659216 0.009614548   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000119487 E001 0.1268540 0.0122592847 4.587570e-01   9 125437393 125437393 1 - 0.000 0.102 10.949
ENSG00000119487 E002 0.2541163 0.0160589266 1.927141e-01   9 125437394 125437398 5 - 0.000 0.184 11.953
ENSG00000119487 E003 17.1528554 0.0008874107 7.031386e-04 0.0113917329 9 125437399 125438468 1070 - 1.129 1.366 0.835
ENSG00000119487 E004 24.7792960 0.0008391962 9.349504e-02 0.3179621478 9 125438469 125438654 186 - 1.361 1.459 0.339
ENSG00000119487 E005 16.5711058 0.0009240732 4.252729e-01 0.7043565847 9 125438655 125438706 52 - 1.271 1.213 -0.203
ENSG00000119487 E006 31.7920755 0.0005367218 6.845451e-01 0.8694483849 9 125438707 125438812 106 - 1.505 1.526 0.069
ENSG00000119487 E007 63.8880665 0.0002476659 1.320704e-01 0.3856122317 9 125438813 125439012 200 - 1.785 1.839 0.180
ENSG00000119487 E008 46.1253505 0.0020241862 7.784443e-01 0.9148664358 9 125444501 125444598 98 - 1.680 1.665 -0.051
ENSG00000119487 E009 0.3723461 0.1568114954 5.304304e-01   9 125447325 125447487 163 - 0.089 0.184 1.224
ENSG00000119487 E010 0.0000000       9 125451058 125451101 44 -      
ENSG00000119487 E011 53.7982435 0.0002785667 4.858733e-01 0.7496810117 9 125467972 125468109 138 - 1.752 1.723 -0.098
ENSG00000119487 E012 0.8630488 0.0152832763 5.621554e-01 0.8021237887 9 125471083 125471237 155 - 0.225 0.313 0.639
ENSG00000119487 E013 2.7727725 0.0053943701 9.499694e-06 0.0003259265 9 125471238 125471905 668 - 0.162 0.799 3.546
ENSG00000119487 E014 0.7355604 0.1065734412 8.523598e-01 0.9478201780 9 125478080 125478182 103 - 0.225 0.254 0.225
ENSG00000119487 E015 49.0229234 0.0004530861 4.564204e-01 0.7287222632 9 125484443 125484583 141 - 1.684 1.714 0.102
ENSG00000119487 E016 0.3621152 0.2468990907 7.316744e-01   9 125505944 125506309 366 - 0.162 0.102 -0.775
ENSG00000119487 E017 28.6249370 0.0106945478 5.140002e-01 0.7707876930 9 125506310 125506417 108 - 1.450 1.494 0.150
ENSG00000119487 E018 4.4032247 0.0036593577 8.901385e-01 0.9632956307 9 125521468 125521765 298 - 0.724 0.740 0.064
ENSG00000119487 E019 43.3449389 0.0035697597 9.937464e-01 1.0000000000 9 125543059 125543168 110 - 1.648 1.645 -0.012
ENSG00000119487 E020 0.3723465 0.0167363812 4.902366e-01   9 125559114 125559632 519 - 0.089 0.184 1.224
ENSG00000119487 E021 46.7597047 0.0055510372 9.179274e-03 0.0759666942 9 125559633 125559782 150 - 1.740 1.601 -0.471
ENSG00000119487 E022 20.0731576 0.0007085068 2.093779e-01 0.4936506738 9 125559783 125559809 27 - 1.361 1.279 -0.288
ENSG00000119487 E023 0.0000000       9 125565366 125565737 372 -      
ENSG00000119487 E024 55.2482322 0.0002585089 5.201412e-01 0.7746105753 9 125585555 125585727 173 - 1.762 1.736 -0.089
ENSG00000119487 E025 0.0000000       9 125595510 125595646 137 -      
ENSG00000119487 E026 0.0000000       9 125599835 125599927 93 -      
ENSG00000119487 E027 0.1187032 0.0118699832 6.303041e-01   9 125650364 125650461 98 - 0.089 0.000 -10.610
ENSG00000119487 E028 0.0000000       9 125652117 125652257 141 -      
ENSG00000119487 E029 18.6225401 0.0007980607 1.943567e-01 0.4742128329 9 125657651 125657668 18 - 1.249 1.335 0.300
ENSG00000119487 E030 47.3685975 0.0003166261 9.730182e-01 0.9950278965 9 125657669 125657799 131 - 1.684 1.684 0.001
ENSG00000119487 E031 28.1749355 0.0005247367 6.513050e-01 0.8531057860 9 125669818 125669886 69 - 1.477 1.451 -0.089
ENSG00000119487 E032 16.4995727 0.0174344996 8.493873e-01 0.9464448423 9 125669887 125669907 21 - 1.232 1.254 0.074
ENSG00000119487 E033 25.4301196 0.0037126205 5.840803e-01 0.8150738263 9 125672316 125672399 84 - 1.406 1.439 0.113
ENSG00000119487 E034 41.2554492 0.0090762647 2.021165e-01 0.4846129782 9 125672400 125672643 244 - 1.661 1.583 -0.265
ENSG00000119487 E035 0.1271363 0.0123492735 4.586376e-01   9 125674149 125674191 43 - 0.000 0.102 10.953
ENSG00000119487 E036 0.0000000       9 125696217 125696404 188 -      
ENSG00000119487 E037 0.1271363 0.0123492735 4.586376e-01   9 125705259 125705287 29 - 0.000 0.102 10.953
ENSG00000119487 E038 26.4784969 0.0005467423 3.445077e-02 0.1773134836 9 125706971 125707234 264 - 1.493 1.371 -0.421

Help

Please Click HERE to learn more details about the results from DEXseq.