ENSG00000119689

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000334220 ENSG00000119689 No_inf pgKDN_inf DLST protein_coding protein_coding 37.7602 37.9289 38.60799 0.8286456 0.6294659 0.02559519 21.926118 16.327539 27.212429 1.7457988 2.9350803 0.7366051 0.58100833 0.432225 0.707550 0.275325 1.099287e-01 9.273684e-13 FALSE TRUE
ENST00000550473 ENSG00000119689 No_inf pgKDN_inf DLST protein_coding retained_intron 37.7602 37.9289 38.60799 0.8286456 0.6294659 0.02559519 1.882299 3.576556 0.000000 0.3268914 0.0000000 -8.4864552 0.05003333 0.094925 0.000000 -0.094925 1.046033e-06 9.273684e-13   FALSE
ENST00000555071 ENSG00000119689 No_inf pgKDN_inf DLST protein_coding retained_intron 37.7602 37.9289 38.60799 0.8286456 0.6294659 0.02559519 3.938587 5.269912 3.068446 0.3985099 0.2643438 -0.7783115 0.10450833 0.138850 0.079775 -0.059075 4.885287e-01 9.273684e-13 FALSE TRUE
MSTRG.8821.19 ENSG00000119689 No_inf pgKDN_inf DLST protein_coding   37.7602 37.9289 38.60799 0.8286456 0.6294659 0.02559519 5.752435 11.721643 0.000000 2.3834696 0.0000000 -10.1961894 0.15309167 0.307050 0.000000 -0.307050 9.273684e-13 9.273684e-13 FALSE TRUE
MSTRG.8821.4 ENSG00000119689 No_inf pgKDN_inf DLST protein_coding   37.7602 37.9289 38.60799 0.8286456 0.6294659 0.02559519 1.799859 0.000000 5.399577 0.0000000 3.2528539 9.0793720 0.04590833 0.000000 0.137725 0.137725 4.751688e-01 9.273684e-13 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000119689 E001 0.0000000       14 74881891 74881902 12 +      
ENSG00000119689 E002 0.1170040 0.0117120068 0.5707265681   14 74881903 74881913 11 + 0.093 0.000 -9.737
ENSG00000119689 E003 0.3532727 0.0157499381 0.1149168887   14 74881914 74881914 1 + 0.235 0.000 -13.345
ENSG00000119689 E004 0.3532727 0.0157499381 0.1149168887   14 74881915 74881915 1 + 0.235 0.000 -13.345
ENSG00000119689 E005 0.5889799 0.0144160960 0.0240822385 1.420907e-01 14 74881916 74881921 6 + 0.341 0.000 -14.030
ENSG00000119689 E006 0.5889799 0.0144160960 0.0240822385 1.420907e-01 14 74881922 74881924 3 + 0.341 0.000 -14.030
ENSG00000119689 E007 3.2539276 0.0046191818 0.0486897333 2.174498e-01 14 74881925 74881940 16 + 0.743 0.478 -1.176
ENSG00000119689 E008 3.8807337 0.0036441614 0.2147852986 5.003123e-01 14 74881941 74881953 13 + 0.762 0.603 -0.666
ENSG00000119689 E009 3.8807337 0.0036441614 0.2147852986 5.003123e-01 14 74881954 74881955 2 + 0.762 0.603 -0.666
ENSG00000119689 E010 7.3060431 0.0021331749 0.4261283339 7.049033e-01 14 74881956 74882016 61 + 0.960 0.876 -0.316
ENSG00000119689 E011 6.1206305 0.0023125154 0.8343318861 9.403559e-01 14 74882591 74882624 34 + 0.843 0.862 0.071
ENSG00000119689 E012 6.1118569 0.0026878298 0.9425151664 9.840065e-01 14 74885586 74885634 49 + 0.858 0.846 -0.044
ENSG00000119689 E013 0.6263978 0.0141598881 0.1533586583 4.179508e-01 14 74885635 74886024 390 + 0.093 0.302 2.071
ENSG00000119689 E014 0.2435110 0.0163612991 0.9630788221   14 74889069 74889075 7 + 0.093 0.097 0.071
ENSG00000119689 E015 0.3707734 0.0166555518 0.5474515899   14 74889076 74889094 19 + 0.093 0.177 1.071
ENSG00000119689 E016 11.7903308 0.0014935719 0.1025096299 3.347514e-01 14 74889095 74889147 53 + 1.172 1.033 -0.501
ENSG00000119689 E017 8.2810270 0.0054517717 0.3471150946 6.376529e-01 14 74889275 74889276 2 + 1.013 0.918 -0.356
ENSG00000119689 E018 17.5489367 0.0008177152 0.1881287259 4.664001e-01 14 74889277 74889349 73 + 1.313 1.219 -0.332
ENSG00000119689 E019 1.6212769 0.0354042447 0.0453355636 2.082201e-01 14 74889350 74889733 384 + 0.235 0.545 1.809
ENSG00000119689 E020 1.2191234 0.0908688468 0.6361975152 8.448693e-01 14 74889878 74889896 19 + 0.386 0.302 -0.514
ENSG00000119689 E021 20.0280716 0.0007058633 0.4738499174 7.407502e-01 14 74889897 74889952 56 + 1.347 1.297 -0.176
ENSG00000119689 E022 14.7322545 0.0010207194 0.1613736455 4.294030e-01 14 74891056 74891067 12 + 1.248 1.140 -0.385
ENSG00000119689 E023 22.2487130 0.0006323207 0.7317131821 8.933811e-01 14 74891068 74891167 100 + 1.379 1.354 -0.087
ENSG00000119689 E024 1.2354562 0.0166800223 0.4750338024 7.416765e-01 14 74891168 74891193 26 + 0.291 0.399 0.656
ENSG00000119689 E025 21.1964664 0.0006906543 0.0000015545 6.827393e-05 14 74891194 74892058 865 + 1.165 1.471 1.071
ENSG00000119689 E026 28.6008060 0.0020307090 0.7430324274 8.983949e-01 14 74892834 74892986 153 + 1.482 1.460 -0.077
ENSG00000119689 E027 22.4841149 0.0170061506 0.7800057857 9.152362e-01 14 74893348 74893424 77 + 1.383 1.358 -0.085
ENSG00000119689 E028 24.8279911 0.0206068950 0.1493348572 4.115741e-01 14 74894312 74894409 98 + 1.469 1.349 -0.414
ENSG00000119689 E029 27.8369520 0.0008797221 0.4565165622 7.288427e-01 14 74898369 74898499 131 + 1.482 1.437 -0.157
ENSG00000119689 E030 22.4089864 0.0015970404 0.7454368677 8.992863e-01 14 74899923 74899996 74 + 1.361 1.377 0.056
ENSG00000119689 E031 22.6192325 0.0006235800 0.7951467121 9.221637e-01 14 74900289 74900372 84 + 1.383 1.363 -0.069
ENSG00000119689 E032 36.6193962 0.0005986885 0.6446070829 8.495107e-01 14 74901066 74901233 168 + 1.566 1.584 0.062
ENSG00000119689 E033 250.1778991 0.0001321359 0.0211207525 1.314258e-01 14 74902196 74903743 1548 + 2.385 2.414 0.100

Help

Please Click HERE to learn more details about the results from DEXseq.