ENSG00000119844

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000238856 ENSG00000119844 No_inf pgKDN_inf AFTPH protein_coding protein_coding 22.45362 21.78729 24.27575 0.5055858 0.6062694 0.1559614 5.183432 0.000000 9.131069 0.0000000 3.1242914 9.8362190 0.22790833 0.00000 0.379150 0.379150 0.006941539 0.006941539 FALSE TRUE
ENST00000409183 ENSG00000119844 No_inf pgKDN_inf AFTPH protein_coding protein_coding 22.45362 21.78729 24.27575 0.5055858 0.6062694 0.1559614 4.809722 4.620490 5.362552 1.0106584 1.0314687 0.2144426 0.21515833 0.21545 0.218150 0.002700 1.000000000 0.006941539 FALSE TRUE
ENST00000487769 ENSG00000119844 No_inf pgKDN_inf AFTPH protein_coding nonsense_mediated_decay 22.45362 21.78729 24.27575 0.5055858 0.6062694 0.1559614 3.988221 7.080460 1.404416 1.1686461 0.8283835 -2.3256723 0.17930833 0.32200 0.056925 -0.265075 0.086179824 0.006941539 TRUE FALSE
MSTRG.16367.1 ENSG00000119844 No_inf pgKDN_inf AFTPH protein_coding   22.45362 21.78729 24.27575 0.5055858 0.6062694 0.1559614 6.326103 8.513481 5.556868 0.3021734 3.5666537 -0.6145770 0.28123333 0.39090 0.222575 -0.168325 0.518115621 0.006941539 FALSE TRUE
MSTRG.16367.9 ENSG00000119844 No_inf pgKDN_inf AFTPH protein_coding   22.45362 21.78729 24.27575 0.5055858 0.6062694 0.1559614 1.155114 0.000000 2.190424 0.0000000 2.1904240 7.7816377 0.05181667 0.00000 0.097300 0.097300 0.855265651 0.006941539 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000119844 E001 0.0000000       2 64524273 64524298 26 +      
ENSG00000119844 E002 0.0000000       2 64524299 64524304 6 +      
ENSG00000119844 E003 0.3707734 0.0164944418 4.865961e-01   2 64524305 64524327 23 + 0.088 0.186 1.250
ENSG00000119844 E004 0.9949077 0.1168933756 1.308859e-01 0.3837564134 2 64524328 64524374 47 + 0.161 0.415 1.836
ENSG00000119844 E005 1.8554056 0.0858071865 1.574947e-01 0.4241355720 2 64524375 64524411 37 + 0.327 0.565 1.251
ENSG00000119844 E006 8.1345881 0.0105972978 2.725077e-01 0.5662202120 2 64524412 64524526 115 + 1.009 0.900 -0.407
ENSG00000119844 E007 7.8855670 0.0033145665 1.493995e-01 0.4116600624 2 64524527 64524612 86 + 1.009 0.870 -0.522
ENSG00000119844 E008 70.0331230 0.0004473439 3.123097e-05 0.0008935868 2 64551443 64552511 1069 + 1.912 1.772 -0.469
ENSG00000119844 E009 36.3725176 0.0248049738 8.481509e-01 0.9462614188 2 64552512 64552875 364 + 1.575 1.569 -0.022
ENSG00000119844 E010 52.4866615 0.0045837118 2.586219e-01 0.5510197029 2 64552876 64553409 534 + 1.700 1.756 0.190
ENSG00000119844 E011 20.0815986 0.0007142367 2.882293e-01 0.5818528044 2 64567562 64567713 152 + 1.288 1.360 0.250
ENSG00000119844 E012 23.7221707 0.0006132439 1.250718e-01 0.3749143263 2 64569092 64569218 127 + 1.432 1.344 -0.304
ENSG00000119844 E013 0.3719991 0.0165052733 4.866526e-01   2 64569219 64569622 404 + 0.088 0.186 1.250
ENSG00000119844 E014 16.5058463 0.0009108991 4.698054e-02 0.2129406833 2 64569623 64569679 57 + 1.303 1.165 -0.487
ENSG00000119844 E015 26.6646629 0.0005361791 2.392469e-01 0.5281843713 2 64572946 64573068 123 + 1.470 1.408 -0.215
ENSG00000119844 E016 0.8894206 0.0124355881 2.329353e-03 0.0286176164 2 64573069 64573405 337 + 0.000 0.458 12.989
ENSG00000119844 E017 13.4593571 0.0013631912 3.595961e-02 0.1819026088 2 64579486 64579546 61 + 1.229 1.067 -0.577
ENSG00000119844 E018 8.8235377 0.0124173321 3.246943e-04 0.0062077505 2 64579547 64581099 1553 + 0.774 1.149 1.406
ENSG00000119844 E019 0.3810317 0.0258062370 7.628679e-02   2 64581100 64581189 90 + 0.000 0.255 11.769
ENSG00000119844 E020 1.5872511 0.0087619321 9.852407e-01 0.9989950641 2 64581190 64581273 84 + 0.410 0.415 0.028
ENSG00000119844 E021 18.8718335 0.0017164528 3.257582e-01 0.6182505430 2 64585422 64585545 124 + 1.326 1.264 -0.219
ENSG00000119844 E022 3.4272361 0.0043558561 6.669503e-01 0.8614753005 2 64591885 64591887 3 + 0.617 0.676 0.250
ENSG00000119844 E023 146.7798056 0.0001386222 7.656201e-05 0.0019002741 2 64591888 64593005 1118 + 2.126 2.212 0.289

Help

Please Click HERE to learn more details about the results from DEXseq.