ENSG00000120314

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358337 ENSG00000120314 No_inf pgKDN_inf WDR55 protein_coding protein_coding 15.18681 13.62143 15.49943 0.5086754 0.3734512 0.1862085 2.920499 0.000000 5.495977 0.0000000 1.9697516 9.10485486 0.18750833 0.00000 0.355600 0.355600 0.0164409961 0.0004036189 FALSE TRUE
ENST00000504897 ENSG00000120314 No_inf pgKDN_inf WDR55 protein_coding nonsense_mediated_decay 15.18681 13.62143 15.49943 0.5086754 0.3734512 0.1862085 1.733469 1.947917 1.829821 0.3299451 0.3172056 -0.08975363 0.11355833 0.14130 0.117550 -0.023750 0.9070861395 0.0004036189 TRUE TRUE
ENST00000511232 ENSG00000120314 No_inf pgKDN_inf WDR55 protein_coding retained_intron 15.18681 13.62143 15.49943 0.5086754 0.3734512 0.1862085 1.537650 1.694637 1.099412 0.1588818 0.2870611 -0.61966923 0.10275000 0.12475 0.070325 -0.054425 0.7537239309 0.0004036189 FALSE TRUE
MSTRG.23663.1 ENSG00000120314 No_inf pgKDN_inf WDR55 protein_coding   15.18681 13.62143 15.49943 0.5086754 0.3734512 0.1862085 7.929210 7.488143 6.366997 0.5812407 1.8617873 -0.23365626 0.52082500 0.55560 0.408800 -0.146800 0.7651922655 0.0004036189 TRUE TRUE
MSTRG.23663.3 ENSG00000120314 No_inf pgKDN_inf WDR55 protein_coding   15.18681 13.62143 15.49943 0.5086754 0.3734512 0.1862085 0.830245 2.490735 0.000000 0.8973822 0.0000000 -7.96620834 0.05943333 0.17830 0.000000 -0.178300 0.0004036189 0.0004036189 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000120314 E001 1.215034 0.0103401486 0.573196170 0.80876256 5 140664839 140664867 29 + 0.386 0.302 -0.515
ENSG00000120314 E002 2.938519 0.0048953295 0.920523236 0.97521456 5 140664868 140664903 36 + 0.587 0.603 0.070
ENSG00000120314 E003 13.905701 0.0013742257 0.356929742 0.64668976 5 140664904 140665103 200 + 1.206 1.140 -0.235
ENSG00000120314 E004 3.472247 0.0056144239 0.045872607 0.20984675 5 140666575 140667043 469 + 0.498 0.761 1.148
ENSG00000120314 E005 2.248368 0.0216114157 0.016377100 0.11124465 5 140667044 140667113 70 + 0.291 0.654 1.877
ENSG00000120314 E006 8.749973 0.0550265197 0.119613552 0.36555062 5 140667114 140668233 1120 + 0.886 1.071 0.690
ENSG00000120314 E007 11.449356 0.0107875923 0.253279098 0.54480683 5 140668234 140668334 101 + 1.143 1.043 -0.363
ENSG00000120314 E008 3.322943 0.0336552375 0.534924240 0.78479419 5 140668335 140668414 80 + 0.587 0.678 0.392
ENSG00000120314 E009 9.697688 0.0013846200 0.020794985 0.12996022 5 140668415 140668502 88 + 1.120 0.918 -0.745
ENSG00000120314 E010 18.717999 0.0137173249 0.939997259 0.98303567 5 140668612 140668791 180 + 1.293 1.297 0.013
ENSG00000120314 E011 7.236536 0.0451846765 0.762292309 0.90725855 5 140668891 140668920 30 + 0.886 0.943 0.217
ENSG00000120314 E012 9.447346 0.0039017188 0.470269784 0.73812109 5 140668921 140668990 70 + 0.982 1.052 0.257
ENSG00000120314 E013 2.749259 0.0052809520 0.007003126 0.06306672 5 140668991 140669078 88 + 0.341 0.721 1.835
ENSG00000120314 E014 18.988524 0.0007663790 0.615582922 0.83317522 5 140669079 140669248 170 + 1.282 1.318 0.126
ENSG00000120314 E015 43.742844 0.0006951065 0.562588098 0.80237719 5 140669333 140669690 358 + 1.636 1.664 0.094
ENSG00000120314 E016 80.708309 0.0002172193 0.041893534 0.19914383 5 140669691 140671268 1578 + 1.938 1.885 -0.180
ENSG00000120314 E017 0.000000       5 140671269 140671321 53 +      
ENSG00000120314 E018 0.000000       5 140671322 140671530 209 +      
ENSG00000120314 E019 17.057768 0.0089094038 0.440137405 0.71591534 5 140671531 140672372 842 + 1.225 1.286 0.215
ENSG00000120314 E020 1.581211 0.0119591564 0.454399486 0.72705535 5 140672378 140674124 1747 + 0.464 0.353 -0.608

Help

Please Click HERE to learn more details about the results from DEXseq.