ENSG00000120699

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000239893 ENSG00000120699 No_inf pgKDN_inf EXOSC8 protein_coding nonsense_mediated_decay 29.20696 28.71416 29.18082 1.611924 1.768885 0.02324976 1.862723 3.652118 0.5133804 2.521179 0.5133804 -2.8067465 0.06035833 0.118675 0.016450 -0.102225 0.44605511 0.03395942 TRUE FALSE
ENST00000474661 ENSG00000120699 No_inf pgKDN_inf EXOSC8 protein_coding protein_coding_CDS_not_defined 29.20696 28.71416 29.18082 1.611924 1.768885 0.02324976 17.941705 11.614369 20.6967067 1.549574 1.0517035 0.8329458 0.61558333 0.414175 0.713850 0.299675 0.03395942 0.03395942   FALSE
ENST00000495092 ENSG00000120699 No_inf pgKDN_inf EXOSC8 protein_coding retained_intron 29.20696 28.71416 29.18082 1.611924 1.768885 0.02324976 1.792788 4.466563 0.9117997 1.874406 0.9117997 -2.2798663 0.05885833 0.147350 0.029225 -0.118125 0.33984743 0.03395942   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000120699 E001 0.1272623 0.0123322094 6.429699e-01   13 36998816 36999194 379 + 0.000 0.088 12.212
ENSG00000120699 E002 0.1272623 0.0123322094 6.429699e-01   13 37000766 37000777 12 + 0.000 0.088 12.217
ENSG00000120699 E003 0.1272623 0.0123322094 6.429699e-01   13 37000778 37000779 2 + 0.000 0.088 12.217
ENSG00000120699 E004 0.1272623 0.0123322094 6.429699e-01   13 37000780 37000780 1 + 0.000 0.088 12.217
ENSG00000120699 E005 0.1272623 0.0123322094 6.429699e-01   13 37000781 37000781 1 + 0.000 0.088 12.217
ENSG00000120699 E006 0.1272623 0.0123322094 6.429699e-01   13 37000782 37000782 1 + 0.000 0.088 12.217
ENSG00000120699 E007 0.2537694 0.0160298989 3.101003e-01   13 37000783 37000785 3 + 0.000 0.162 13.217
ENSG00000120699 E008 0.2537694 0.0160298989 3.101003e-01   13 37000786 37000786 1 + 0.000 0.162 13.217
ENSG00000120699 E009 0.2537694 0.0160298989 3.101003e-01   13 37000787 37000787 1 + 0.000 0.162 13.217
ENSG00000120699 E010 0.2537694 0.0160298989 3.101003e-01   13 37000788 37000788 1 + 0.000 0.162 13.217
ENSG00000120699 E011 0.2537694 0.0160298989 3.101003e-01   13 37000789 37000790 2 + 0.000 0.162 13.217
ENSG00000120699 E012 3.7894450 0.0125755945 3.172926e-01 0.610083742 13 37000791 37000806 16 + 0.741 0.619 -0.512
ENSG00000120699 E013 7.7897856 0.0019583748 2.716258e-02 0.153193196 13 37000807 37000822 16 + 1.045 0.837 -0.779
ENSG00000120699 E014 1.0980294 0.0117491214 5.508216e-01 0.794907437 13 37000823 37000884 62 + 0.367 0.280 -0.554
ENSG00000120699 E015 2.8256364 0.1759350726 7.854899e-01 0.917380082 13 37000885 37001280 396 + 0.593 0.570 -0.107
ENSG00000120699 E016 0.0000000       13 37001281 37001298 18 +      
ENSG00000120699 E017 2.3529672 0.0155546495 4.562246e-01 0.728678498 13 37001299 37001723 425 + 0.456 0.569 0.546
ENSG00000120699 E018 0.8719200 0.0131137806 3.613613e-01 0.650810059 13 37001724 37001748 25 + 0.185 0.328 1.090
ENSG00000120699 E019 0.9816516 0.0870486135 8.267933e-01 0.937265248 13 37001749 37001801 53 + 0.314 0.280 -0.232
ENSG00000120699 E020 2.8228279 0.0053124817 8.287180e-01 0.938047270 13 37001802 37002248 447 + 0.593 0.569 -0.106
ENSG00000120699 E021 0.1272623 0.0123322094 6.429699e-01   13 37002249 37002272 24 + 0.000 0.088 12.217
ENSG00000120699 E022 12.2866965 0.0011375833 4.997013e-03 0.049578535 13 37002273 37002309 37 + 1.228 1.011 -0.781
ENSG00000120699 E023 0.6361857 0.3299744432 1.034180e-01 0.336150477 13 37002310 37002487 178 + 0.000 0.328 14.540
ENSG00000120699 E024 18.5039971 0.0007855642 1.097227e-03 0.016094054 13 37002488 37002551 64 + 1.391 1.183 -0.730
ENSG00000120699 E025 16.0302391 0.0009128325 1.938583e-01 0.473702183 13 37002934 37003007 74 + 1.273 1.189 -0.298
ENSG00000120699 E026 11.9510144 0.0023086840 3.967569e-01 0.681331470 13 37003008 37003494 487 + 1.065 1.142 0.279
ENSG00000120699 E027 2.1222999 0.0067114810 6.225760e-02 0.250600914 13 37003495 37003517 23 + 0.314 0.595 1.469
ENSG00000120699 E028 13.9203572 0.0010339387 9.241071e-04 0.014143244 13 37003518 37004217 700 + 1.001 1.270 0.966
ENSG00000120699 E029 10.5723599 0.0033898109 1.273407e-03 0.018026232 13 37004218 37004476 259 + 0.867 1.170 1.114
ENSG00000120699 E030 3.9798670 0.0057272620 4.621744e-02 0.210818787 13 37004477 37004515 39 + 0.530 0.792 1.122
ENSG00000120699 E031 14.5402358 0.0009070823 3.733812e-01 0.661098435 13 37004516 37004561 46 + 1.146 1.220 0.262
ENSG00000120699 E032 8.2356736 0.0030863462 3.958928e-04 0.007235541 13 37004562 37005844 1283 + 0.720 1.090 1.412
ENSG00000120699 E033 0.9592490 0.0935823143 1.196127e-01 0.365550619 13 37005865 37005919 55 + 0.413 0.162 -1.816
ENSG00000120699 E034 13.8695843 0.0009873592 7.722667e-01 0.912292682 13 37005920 37005956 37 + 1.178 1.163 -0.053
ENSG00000120699 E035 20.6307120 0.0007333522 8.169517e-01 0.933368637 13 37005957 37006025 69 + 1.336 1.329 -0.025
ENSG00000120699 E036 0.3729107 0.1532245301 7.305932e-01   13 37006026 37006114 89 + 0.102 0.162 0.768
ENSG00000120699 E037 18.2087820 0.0009457020 9.308548e-02 0.316977166 13 37006115 37006160 46 + 1.336 1.231 -0.368
ENSG00000120699 E038 0.6100306 0.3796303644 7.282697e-01 0.891659394 13 37006161 37006321 161 + 0.254 0.162 -0.818
ENSG00000120699 E039 1.2333165 0.0113379176 7.277673e-01 0.891319282 13 37006322 37006974 653 + 0.314 0.372 0.353
ENSG00000120699 E040 11.7375550 0.0082003922 3.252566e-01 0.617754985 13 37006975 37006977 3 + 1.146 1.065 -0.292
ENSG00000120699 E041 22.9288120 0.0008056522 5.714984e-01 0.807672225 13 37006978 37007071 94 + 1.391 1.364 -0.093
ENSG00000120699 E042 7.8554084 0.0019096019 8.342109e-01 0.940355913 13 37008057 37008061 5 + 0.952 0.938 -0.051
ENSG00000120699 E043 24.8811083 0.0007837254 4.288740e-01 0.707258474 13 37008062 37008177 116 + 1.431 1.393 -0.132
ENSG00000120699 E044 22.5951864 0.0006459560 3.863425e-02 0.190119849 13 37008729 37008835 107 + 1.431 1.315 -0.404
ENSG00000120699 E045 5.6280985 0.0286597807 4.110321e-01 0.692742413 13 37008836 37009183 348 + 0.867 0.776 -0.357
ENSG00000120699 E046 22.4143902 0.0008974784 3.716251e-01 0.659630677 13 37009184 37011095 1912 + 1.331 1.393 0.216
ENSG00000120699 E047 0.7250847 0.0140304343 3.029191e-01 0.596045864 13 37019631 37019744 114 + 0.314 0.162 -1.232
ENSG00000120699 E048 9.8674887 0.0098073081 8.424624e-05 0.002061587 13 37019745 37023409 3665 + 0.762 1.170 1.529
ENSG00000120699 E049 1.3782362 0.0950221100 9.092270e-02 0.313068744 13 37025340 37025881 542 + 0.185 0.482 1.939

Help

Please Click HERE to learn more details about the results from DEXseq.