ENSG00000120708

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000442011 ENSG00000120708 No_inf pgKDN_inf TGFBI protein_coding protein_coding 337.2521 272.8585 320.6369 1.989208 6.51878 0.2327794 156.87356 105.75374 156.590222 2.252106 1.622914 0.5662411 0.45826667 0.387675 0.488875 0.101200 0.009171067 0.0005740077 FALSE TRUE
ENST00000503087 ENSG00000120708 No_inf pgKDN_inf TGFBI protein_coding protein_coding 337.2521 272.8585 320.6369 1.989208 6.51878 0.2327794 16.85174 30.13223 9.090757 11.422828 9.090757 -1.7277279 0.05498333 0.110050 0.028700 -0.081350 0.331101963 0.0005740077   FALSE
ENST00000508076 ENSG00000120708 No_inf pgKDN_inf TGFBI protein_coding protein_coding 337.2521 272.8585 320.6369 1.989208 6.51878 0.2327794 99.82307 81.17051 99.284557 10.077790 10.565514 0.2905812 0.29732500 0.297975 0.308825 0.010850 0.961069008 0.0005740077   FALSE
ENST00000514554 ENSG00000120708 No_inf pgKDN_inf TGFBI protein_coding protein_coding 337.2521 272.8585 320.6369 1.989208 6.51878 0.2327794 54.07056 44.75025 49.387139 4.527209 4.865070 0.1422093 0.16021667 0.163800 0.154175 -0.009625 0.930062899 0.0005740077 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000120708 E001 1.3135890 1.994621e-02 5.522700e-02 0.234149292 5 136028988 136028990 3 + 0.484 0.184 -1.957
ENSG00000120708 E002 56.0256482 2.588917e-04 4.311809e-03 0.044721750 5 136028991 136029138 148 + 1.808 1.692 -0.390
ENSG00000120708 E003 35.6451114 3.825528e-04 6.596925e-02 0.258683213 5 136029139 136029189 51 + 1.606 1.513 -0.315
ENSG00000120708 E004 65.1545784 3.621283e-03 1.140592e-01 0.355608445 5 136033763 136033861 99 + 1.853 1.782 -0.238
ENSG00000120708 E005 65.2554428 4.405324e-04 4.620856e-02 0.210811430 5 136044058 136044122 65 + 1.856 1.780 -0.254
ENSG00000120708 E006 0.1272623 1.234921e-02 4.647386e-01   5 136044782 136044870 89 + 0.000 0.102 11.501
ENSG00000120708 E007 0.8409865 3.891606e-02 3.502644e-01 0.640508646 5 136045745 136046334 590 + 0.330 0.184 -1.109
ENSG00000120708 E008 121.4976737 9.347220e-04 5.347798e-02 0.230245200 5 136046335 136046495 161 + 2.114 2.057 -0.192
ENSG00000120708 E009 5.4334121 2.848910e-03 4.874765e-02 0.217526647 5 136046496 136046556 61 + 0.687 0.909 0.880
ENSG00000120708 E010 14.4961230 4.056477e-03 5.837483e-05 0.001511468 5 136046557 136046850 294 + 1.004 1.328 1.158
ENSG00000120708 E011 172.4098652 1.113127e-04 2.647554e-01 0.557807688 5 136046851 136047015 165 + 2.251 2.225 -0.084
ENSG00000120708 E012 0.2533610 1.604760e-02 1.962843e-01   5 136047016 136047273 258 + 0.000 0.184 12.407
ENSG00000120708 E013 109.7272949 2.228935e-03 1.450564e-01 0.405414695 5 136047274 136047323 50 + 2.067 2.017 -0.168
ENSG00000120708 E014 76.3275639 3.011673e-04 1.747411e-01 0.448551939 5 136047324 136047352 29 + 1.910 1.863 -0.158
ENSG00000120708 E015 114.9201040 1.406997e-04 3.099187e-01 0.603195707 5 136047353 136047417 65 + 2.077 2.049 -0.095
ENSG00000120708 E016 59.6011968 2.399329e-04 9.383441e-01 0.982232547 5 136047418 136047420 3 + 1.781 1.784 0.012
ENSG00000120708 E017 1.6060380 1.734229e-01 4.189542e-01 0.698715283 5 136047421 136048252 832 + 0.330 0.493 0.891
ENSG00000120708 E018 0.7600184 1.381182e-01 1.217729e-02 0.091383014 5 136048253 136048349 97 + 0.000 0.412 13.097
ENSG00000120708 E019 1.8718588 2.076044e-01 8.561206e-02 0.302800246 5 136048350 136049438 1089 + 0.281 0.591 1.671
ENSG00000120708 E020 119.0396276 1.365919e-04 2.666642e-01 0.560078809 5 136049439 136049515 77 + 2.093 2.063 -0.102
ENSG00000120708 E021 109.3062032 2.006438e-03 1.314785e-01 0.384648051 5 136049516 136049580 65 + 2.066 2.015 -0.172
ENSG00000120708 E022 0.7622843 1.366922e-02 5.779123e-03 0.054942926 5 136049581 136049807 227 + 0.000 0.412 14.028
ENSG00000120708 E023 164.9263622 3.114146e-03 4.191450e-01 0.698759164 5 136052907 136053017 111 + 2.207 2.233 0.087
ENSG00000120708 E024 175.0702345 1.061815e-04 3.555983e-01 0.645382786 5 136053018 136053119 102 + 2.235 2.256 0.072
ENSG00000120708 E025 202.6578823 4.342549e-04 8.137775e-01 0.931892610 5 136053943 136054080 138 + 2.306 2.312 0.020
ENSG00000120708 E026 1.4864290 6.132042e-02 1.955188e-01 0.475884971 5 136054675 136054715 41 + 0.281 0.493 1.213
ENSG00000120708 E027 226.4753839 1.506846e-04 7.168888e-01 0.885917063 5 136054716 136054861 146 + 2.353 2.361 0.026
ENSG00000120708 E028 1.4696164 1.424321e-02 8.039401e-01 0.927162963 5 136054862 136055392 531 + 0.374 0.412 0.213
ENSG00000120708 E029 0.2536433 1.602174e-02 1.963508e-01   5 136055499 136055679 181 + 0.000 0.184 12.407
ENSG00000120708 E030 198.9515220 1.028717e-04 9.567756e-01 0.989750547 5 136055680 136055816 137 + 2.300 2.301 0.005
ENSG00000120708 E031 0.2457744 1.652106e-02 9.094119e-01   5 136056449 136056530 82 + 0.089 0.102 0.213
ENSG00000120708 E032 207.9936179 9.550321e-05 5.343765e-01 0.784460084 5 136056665 136056795 131 + 2.326 2.313 -0.042
ENSG00000120708 E033 0.0000000       5 136058767 136058848 82 +      
ENSG00000120708 E034 0.0000000       5 136058849 136058919 71 +      
ENSG00000120708 E035 0.4894115 1.585007e-02 8.843506e-01   5 136058920 136059089 170 + 0.163 0.184 0.213
ENSG00000120708 E036 189.3961415 1.168996e-04 1.049495e-01 0.338780512 5 136059090 136059185 96 + 2.296 2.261 -0.117
ENSG00000120708 E037 106.1642482 1.732133e-04 1.089868e-01 0.346585798 5 136059186 136059214 29 + 2.052 2.005 -0.157
ENSG00000120708 E038 200.8568032 9.744474e-05 7.227749e-01 0.888603311 5 136060834 136060936 103 + 2.301 2.309 0.027
ENSG00000120708 E039 1.2354562 1.433490e-02 3.950929e-01 0.679884487 5 136061190 136061499 310 + 0.281 0.412 0.798
ENSG00000120708 E040 166.2863280 3.095556e-04 1.348043e-02 0.097591046 5 136061500 136061579 80 + 2.193 2.253 0.200
ENSG00000120708 E041 111.0615523 1.648910e-04 7.031682e-01 0.879214832 5 136062663 136062687 25 + 2.044 2.055 0.038
ENSG00000120708 E042 919.6265349 5.026804e-05 4.700606e-05 0.001268247 5 136063186 136063818 633 + 2.945 2.983 0.125

Help

Please Click HERE to learn more details about the results from DEXseq.