ENSG00000120899

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000346049 ENSG00000120899 No_inf pgKDN_inf PTK2B protein_coding protein_coding 170.1692 164.8475 163.4022 4.585767 4.221217 -0.01270366 80.11711 60.71221 86.510579 0.4834749 1.3952320 0.5108190 0.471200 0.369350 0.531125 0.161775 2.293347e-03 9.218803e-11 FALSE TRUE
MSTRG.27433.15 ENSG00000120899 No_inf pgKDN_inf PTK2B protein_coding   170.1692 164.8475 163.4022 4.585767 4.221217 -0.01270366 37.98925 34.05210 40.983907 0.3904139 1.2266679 0.2672419 0.223475 0.207050 0.250900 0.043850 5.329054e-01 9.218803e-11 FALSE TRUE
MSTRG.27433.23 ENSG00000120899 No_inf pgKDN_inf PTK2B protein_coding   170.1692 164.8475 163.4022 4.585767 4.221217 -0.01270366 15.68108 30.34614 7.210302 0.4826798 0.2021938 -2.0718572 0.093625 0.184425 0.044325 -0.140100 9.218803e-11 9.218803e-11 FALSE TRUE
MSTRG.27433.24 ENSG00000120899 No_inf pgKDN_inf PTK2B protein_coding   170.1692 164.8475 163.4022 4.585767 4.221217 -0.01270366 10.99386 16.70150 7.027901 1.7443299 2.1027430 -1.2476243 0.064400 0.100775 0.042100 -0.058675 1.264762e-01 9.218803e-11 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000120899 E001 0.2372762 2.481130e-01 2.339563e-01   8 27311482 27311566 85 + 0.186 0.000 -10.330
ENSG00000120899 E002 0.2452102 1.642655e-02 8.857804e-01   8 27311567 27311628 62 + 0.103 0.088 -0.258
ENSG00000120899 E003 0.3638483 1.660533e-02 4.752729e-01   8 27311629 27311709 81 + 0.186 0.088 -1.258
ENSG00000120899 E004 0.5978563 1.507671e-02 1.181233e-01 3.630917e-01 8 27312304 27312387 84 + 0.316 0.088 -2.258
ENSG00000120899 E005 0.4799735 3.007538e-02 2.420249e-01   8 27313205 27313287 83 + 0.256 0.088 -1.843
ENSG00000120899 E006 0.4884040 1.578384e-02 8.541262e-01   8 27322402 27322461 60 + 0.186 0.161 -0.258
ENSG00000120899 E007 0.2435110 1.626427e-02 8.857040e-01   8 27322462 27322499 38 + 0.103 0.088 -0.258
ENSG00000120899 E008 0.0000000       8 27322667 27322817 151 +      
ENSG00000120899 E009 0.6251106 1.490008e-02 2.450505e-01 5.354951e-01 8 27323267 27323426 160 + 0.103 0.278 1.742
ENSG00000120899 E010 0.0000000       8 27325345 27325432 88 +      
ENSG00000120899 E011 5.4734601 2.530600e-03 5.239587e-02 2.274747e-01 8 27325552 27325563 12 + 0.915 0.701 -0.843
ENSG00000120899 E012 31.4865684 4.278304e-04 2.103219e-03 2.655936e-02 8 27325564 27325681 118 + 1.591 1.431 -0.550
ENSG00000120899 E013 0.7440284 1.323447e-02 5.519904e-01 7.956742e-01 8 27326823 27326883 61 + 0.186 0.278 0.742
ENSG00000120899 E014 0.1186381 1.179383e-02 4.465558e-01   8 27380651 27380653 3 + 0.103 0.000 -12.561
ENSG00000120899 E015 0.7103246 2.438295e-02 5.359228e-03 5.209888e-02 8 27380654 27380792 139 + 0.416 0.000 -14.869
ENSG00000120899 E016 0.6166128 1.431160e-02 8.097166e-01 9.298226e-01 8 27396056 27396295 240 + 0.186 0.223 0.327
ENSG00000120899 E017 0.1268540 1.228143e-02 6.461493e-01   8 27397452 27397547 96 + 0.000 0.088 11.345
ENSG00000120899 E018 101.5790010 4.875978e-04 3.925256e-09 3.002904e-07 8 27397548 27397788 241 + 2.099 1.920 -0.603
ENSG00000120899 E019 0.1268540 1.228143e-02 6.461493e-01   8 27397789 27397789 1 + 0.000 0.088 11.345
ENSG00000120899 E020 85.6816423 1.812972e-04 1.097086e-11 1.240467e-09 8 27419895 27420073 179 + 2.044 1.825 -0.738
ENSG00000120899 E021 58.7001694 6.655481e-03 6.816289e-05 1.718241e-03 8 27420657 27420744 88 + 1.876 1.671 -0.693
ENSG00000120899 E022 0.0000000       8 27422276 27422303 28 +      
ENSG00000120899 E023 52.6919898 1.177106e-03 1.218097e-02 9.138698e-02 8 27422304 27422383 80 + 1.783 1.677 -0.359
ENSG00000120899 E024 0.0000000       8 27422384 27422385 2 +      
ENSG00000120899 E025 43.9422789 3.643913e-04 5.861300e-02 2.425918e-01 8 27430093 27430155 63 + 1.694 1.611 -0.282
ENSG00000120899 E026 45.4925573 3.204558e-04 1.710550e-02 1.143621e-01 8 27430364 27430418 55 + 1.719 1.616 -0.351
ENSG00000120899 E027 33.8874969 8.058208e-04 7.221836e-02 2.726463e-01 8 27430876 27430886 11 + 1.588 1.497 -0.310
ENSG00000120899 E028 39.9450805 3.926217e-04 7.060910e-03 6.343880e-02 8 27430887 27430898 12 + 1.675 1.550 -0.426
ENSG00000120899 E029 76.3034155 1.909113e-04 1.504280e-05 4.843691e-04 8 27430899 27431016 118 + 1.961 1.814 -0.494
ENSG00000120899 E030 15.7741787 1.119053e-03 1.420520e-01 4.009750e-01 8 27431017 27431397 381 + 1.277 1.172 -0.370
ENSG00000120899 E031 60.1318837 2.384126e-04 3.750759e-02 1.866692e-01 8 27431398 27431472 75 + 1.825 1.747 -0.264
ENSG00000120899 E032 0.2438580 1.612983e-02 8.857577e-01   8 27432103 27432259 157 + 0.103 0.088 -0.258
ENSG00000120899 E033 73.4202777 2.040288e-04 1.259822e-04 2.865762e-03 8 27432260 27432361 102 + 1.938 1.805 -0.446
ENSG00000120899 E034 54.7567799 2.625499e-04 3.671575e-08 2.340694e-06 8 27433435 27433513 79 + 1.854 1.632 -0.750
ENSG00000120899 E035 39.4839946 3.446362e-04 2.843603e-05 8.290102e-04 8 27433514 27433552 39 + 1.703 1.507 -0.671
ENSG00000120899 E036 44.5628400 1.066044e-03 1.471513e-06 6.489338e-05 8 27434093 27434132 40 + 1.766 1.544 -0.752
ENSG00000120899 E037 51.5265561 2.761098e-04 8.292429e-07 3.937006e-05 8 27434513 27434559 47 + 1.820 1.616 -0.691
ENSG00000120899 E038 62.2269878 2.504306e-04 2.966859e-08 1.925566e-06 8 27435743 27435793 51 + 1.903 1.693 -0.708
ENSG00000120899 E039 104.4254293 1.115181e-03 9.417360e-10 8.074974e-08 8 27436251 27436348 98 + 2.118 1.923 -0.655
ENSG00000120899 E040 118.7377975 1.143291e-03 9.411073e-10 8.074974e-08 8 27437122 27437206 85 + 2.169 1.984 -0.622
ENSG00000120899 E041 88.0852199 2.111480e-04 2.027788e-07 1.104714e-05 8 27437396 27437454 59 + 2.032 1.866 -0.555
ENSG00000120899 E042 70.2539724 2.208568e-03 1.733396e-05 5.454431e-04 8 27437455 27437496 42 + 1.938 1.766 -0.580
ENSG00000120899 E043 105.6485726 1.657573e-04 4.941903e-05 1.316230e-03 8 27437765 27437880 116 + 2.086 1.969 -0.392
ENSG00000120899 E044 0.1272623 1.234201e-02 6.461884e-01   8 27437881 27437992 112 + 0.000 0.088 11.344
ENSG00000120899 E045 94.0916982 1.820273e-04 1.414570e-05 4.607090e-04 8 27439031 27439131 101 + 2.044 1.912 -0.446
ENSG00000120899 E046 91.3223430 1.495046e-03 1.740836e-05 5.474650e-04 8 27439309 27439398 90 + 2.039 1.891 -0.498
ENSG00000120899 E047 179.4081740 1.180927e-03 4.520110e-07 2.257292e-05 8 27440237 27440441 205 + 2.321 2.191 -0.435
ENSG00000120899 E048 115.5896046 1.614003e-03 3.922093e-04 7.179893e-03 8 27442875 27442983 109 + 2.123 2.010 -0.378
ENSG00000120899 E049 0.1265070 1.229323e-02 6.461693e-01   8 27444141 27444149 9 + 0.000 0.088 11.345
ENSG00000120899 E050 6.9732066 1.963687e-03 4.119229e-01 6.934684e-01 8 27444150 27444205 56 + 0.943 0.861 -0.309
ENSG00000120899 E051 82.4095972 6.284861e-03 1.589263e-02 1.093029e-01 8 27444206 27444271 66 + 1.976 1.866 -0.369
ENSG00000120899 E052 72.0144919 2.276927e-04 2.278522e-33 1.575510e-30 8 27444272 27445272 1001 + 1.527 2.011 1.638
ENSG00000120899 E053 47.3760982 1.387257e-02 5.523489e-11 5.762164e-09 8 27445273 27445793 521 + 1.361 1.829 1.598
ENSG00000120899 E054 105.7881940 1.519695e-04 3.591170e-03 3.946335e-02 8 27445794 27445919 126 + 2.070 1.987 -0.278
ENSG00000120899 E055 563.9632009 8.197468e-05 0.000000e+00 0.000000e+00 8 27445920 27450748 4829 + 2.309 2.923 2.046
ENSG00000120899 E056 196.5014204 1.021971e-04 8.933600e-01 9.646528e-01 8 27450749 27450895 147 + 2.289 2.295 0.019
ENSG00000120899 E057 94.0768284 4.026533e-04 2.065313e-01 4.902072e-01 8 27451043 27451078 36 + 1.996 1.958 -0.126
ENSG00000120899 E058 89.8367337 2.002645e-03 1.364878e-01 3.930045e-01 8 27451485 27451509 25 + 1.984 1.931 -0.175
ENSG00000120899 E059 68.0076426 2.301247e-04 1.067230e-10 1.063955e-08 8 27451510 27452856 1347 + 1.677 1.928 0.846
ENSG00000120899 E060 14.0640502 1.611462e-03 1.197373e-04 2.755081e-03 8 27452857 27453113 257 + 0.968 1.287 1.145
ENSG00000120899 E061 107.9936180 1.492146e-04 6.740927e-02 2.619534e-01 8 27453114 27453160 47 + 2.062 2.011 -0.170
ENSG00000120899 E062 2.2421956 1.987166e-02 1.413796e-01 3.999271e-01 8 27454031 27454153 123 + 0.369 0.592 1.120
ENSG00000120899 E063 190.1801489 1.097408e-04 4.431892e-01 7.182382e-01 8 27454154 27454291 138 + 2.286 2.272 -0.047
ENSG00000120899 E064 2.4864618 1.284647e-02 1.721969e-01 4.448410e-01 8 27454292 27454530 239 + 0.416 0.616 0.964
ENSG00000120899 E065 163.6224446 1.006734e-03 8.047340e-01 9.277029e-01 8 27454531 27454611 81 + 2.208 2.217 0.031
ENSG00000120899 E066 991.4075529 2.030491e-04 6.570240e-01 8.564962e-01 8 27458294 27459391 1098 + 2.989 2.996 0.024

Help

Please Click HERE to learn more details about the results from DEXseq.