ENSG00000120925

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000319073 ENSG00000120925 No_inf pgKDN_inf RNF170 protein_coding protein_coding 28.56626 15.79595 29.89124 0.9556675 6.171022 0.9197369 4.096352 0.7152725 5.6288090 0.7152725 2.7726594 2.9587954 0.16682500 0.038825 0.250800 0.211975 0.409097256 0.005151596 TRUE TRUE
ENST00000524954 ENSG00000120925 No_inf pgKDN_inf RNF170 protein_coding protein_coding 28.56626 15.79595 29.89124 0.9556675 6.171022 0.9197369 9.224223 0.0000000 5.9350426 0.0000000 5.9350426 9.2155433 0.15376667 0.000000 0.125550 0.125550 0.881997847 0.005151596   FALSE
ENST00000526349 ENSG00000120925 No_inf pgKDN_inf RNF170 protein_coding protein_coding 28.56626 15.79595 29.89124 0.9556675 6.171022 0.9197369 4.225972 3.9987991 5.3317173 0.3431180 2.5910616 0.4141335 0.17560833 0.252475 0.157550 -0.094925 0.749291312 0.005151596 FALSE TRUE
ENST00000527424 ENSG00000120925 No_inf pgKDN_inf RNF170 protein_coding protein_coding 28.56626 15.79595 29.89124 0.9556675 6.171022 0.9197369 5.574920 3.9039737 7.2928829 2.2809355 1.4740871 0.8998320 0.25686667 0.271500 0.273825 0.002325 0.834289373 0.005151596 FALSE TRUE
ENST00000583919 ENSG00000120925 No_inf pgKDN_inf RNF170 protein_coding miRNA 28.56626 15.79595 29.89124 0.9556675 6.171022 0.9197369 1.185099 0.0000000 2.4475498 0.0000000 2.4475498 7.9410769 0.03200000 0.000000 0.081325 0.081325 0.914566335 0.005151596   FALSE
MSTRG.27627.4 ENSG00000120925 No_inf pgKDN_inf RNF170 protein_coding   28.56626 15.79595 29.89124 0.9556675 6.171022 0.9197369 1.383425 1.9915215 1.3369078 1.9915215 0.6802687 -0.5714460 0.07360833 0.124350 0.053125 -0.071225 0.804471908 0.005151596 FALSE TRUE
MSTRG.27627.5 ENSG00000120925 No_inf pgKDN_inf RNF170 protein_coding   28.56626 15.79595 29.89124 0.9556675 6.171022 0.9197369 1.269120 3.4236496 0.3837111 1.4948204 0.2479528 -3.1245335 0.07125833 0.204175 0.009600 -0.194575 0.005151596 0.005151596 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000120925 E001 0.9800501 0.0891485051 9.578043e-01 9.899059e-01 8 42849637 42850997 1361 - 0.291 0.302 0.070
ENSG00000120925 E002 0.0000000       8 42853297 42853300 4 -      
ENSG00000120925 E003 0.0000000       8 42853301 42853337 37 -      
ENSG00000120925 E004 0.9706993 0.0502535719 5.452636e-01 7.912919e-01 8 42853338 42853378 41 - 0.341 0.244 -0.666
ENSG00000120925 E005 98.8453033 0.0003496558 1.340681e-06 6.010662e-05 8 42853379 42855247 1869 - 1.935 2.055 0.403
ENSG00000120925 E006 15.0267140 0.0010586249 6.055306e-01 8.280558e-01 8 42855248 42855706 459 - 1.224 1.185 -0.141
ENSG00000120925 E007 2.1667275 0.0082403549 7.528861e-02 2.801145e-01 8 42855707 42855708 2 - 0.613 0.353 -1.308
ENSG00000120925 E008 74.2397724 0.0003164414 1.469372e-01 4.080021e-01 8 42855709 42856428 720 - 1.899 1.853 -0.157
ENSG00000120925 E009 2.3607670 0.0063266660 8.450295e-02 3.002360e-01 8 42861330 42861744 415 - 0.386 0.630 1.186
ENSG00000120925 E010 18.7198945 0.0007967346 9.235409e-01 9.766915e-01 8 42861745 42861855 111 - 1.293 1.297 0.014
ENSG00000120925 E011 11.1400103 0.0307724678 7.547310e-01 9.035179e-01 8 42865416 42865465 50 - 1.070 1.098 0.103
ENSG00000120925 E012 8.4339974 0.0020143600 8.939762e-01 9.649511e-01 8 42865466 42865489 24 - 0.982 0.967 -0.055
ENSG00000120925 E013 14.2323107 0.0014558639 9.649720e-02 3.235170e-01 8 42870004 42870112 109 - 1.243 1.115 -0.453
ENSG00000120925 E014 11.4578199 0.0099444424 3.712409e-01 6.593081e-01 8 42873931 42874006 76 - 1.135 1.053 -0.299
ENSG00000120925 E015 14.1257904 0.0269432721 2.381304e-01 5.270705e-01 8 42887728 42887848 121 - 1.237 1.115 -0.432
ENSG00000120925 E016 7.2819728 0.0189881862 9.305773e-02 3.169437e-01 8 42887849 42887871 23 - 1.003 0.814 -0.718
ENSG00000120925 E017 1.8337849 0.0509770654 8.805720e-01 9.597939e-01 8 42889303 42889414 112 - 0.464 0.440 -0.122
ENSG00000120925 E018 0.7453828 0.0564592249 3.893636e-01 6.750594e-01 8 42893168 42893261 94 - 0.170 0.302 1.071
ENSG00000120925 E019 0.6171781 0.0244472083 6.147812e-01 8.326849e-01 8 42893953 42893975 23 - 0.170 0.244 0.656
ENSG00000120925 E020 0.3641302 0.2017779533 6.638077e-01   8 42896197 42896253 57 - 0.170 0.097 -0.930
ENSG00000120925 E021 1.3432666 0.0093023291 8.344759e-01 9.403559e-01 8 42896254 42896483 230 - 0.386 0.353 -0.192
ENSG00000120925 E022 6.2688983 0.0099747784 5.664019e-03 5.416368e-02 8 42896484 42896723 240 - 0.993 0.678 -1.232
ENSG00000120925 E023 0.1176306 0.0117421485 5.681171e-01   8 42897240 42897290 51 - 0.093 0.000 -8.310

Help

Please Click HERE to learn more details about the results from DEXseq.