ENSG00000120948

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000240185 ENSG00000120948 No_inf pgKDN_inf TARDBP protein_coding protein_coding 141.7977 100.9892 164.9831 3.994176 7.707369 0.7080624 6.449306 8.988057 4.799048 0.4139932 0.5526829 -0.9038622 0.05133333 0.089500 0.029650 -0.059850 1.787394e-02 2.631885e-06 FALSE TRUE
ENST00000315091 ENSG00000120948 No_inf pgKDN_inf TARDBP protein_coding protein_coding 141.7977 100.9892 164.9831 3.994176 7.707369 0.7080624 29.335863 15.262561 40.409458 1.0201928 2.0601106 1.4041080 0.20035833 0.152525 0.245300 0.092775 8.911321e-02 2.631885e-06 FALSE TRUE
ENST00000439080 ENSG00000120948 No_inf pgKDN_inf TARDBP protein_coding nonsense_mediated_decay 141.7977 100.9892 164.9831 3.994176 7.707369 0.7080624 19.541546 5.466017 29.107343 2.1268072 4.3801941 2.4106800 0.12724167 0.056475 0.174550 0.118075 2.786469e-01 2.631885e-06 FALSE TRUE
ENST00000607145 ENSG00000120948 No_inf pgKDN_inf TARDBP protein_coding protein_coding_CDS_not_defined 141.7977 100.9892 164.9831 3.994176 7.707369 0.7080624 8.619638 13.460990 4.746292 0.5700940 0.4791593 -1.5019467 0.07034167 0.133650 0.028850 -0.104800 2.631885e-06 2.631885e-06   FALSE
ENST00000617757 ENSG00000120948 No_inf pgKDN_inf TARDBP protein_coding protein_coding_CDS_not_defined 141.7977 100.9892 164.9831 3.994176 7.707369 0.7080624 18.399156 7.975093 21.757967 4.7199878 7.4453412 1.4468255 0.11930833 0.074325 0.126125 0.051800 8.342894e-01 2.631885e-06   FALSE
ENST00000621573 ENSG00000120948 No_inf pgKDN_inf TARDBP protein_coding nonsense_mediated_decay 141.7977 100.9892 164.9831 3.994176 7.707369 0.7080624 35.635716 20.787827 47.015813 1.8809132 1.7813831 1.1770201 0.24572500 0.206050 0.287575 0.081525 3.627976e-01 2.631885e-06   FALSE
MSTRG.234.11 ENSG00000120948 No_inf pgKDN_inf TARDBP protein_coding   141.7977 100.9892 164.9831 3.994176 7.707369 0.7080624 10.481820 17.993190 3.510463 1.6948498 2.9464156 -2.3544156 0.08855833 0.177475 0.024075 -0.153400 1.516386e-02 2.631885e-06 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000120948 E001 0.1271363 0.0123325269 4.923386e-01   1 11012344 11012423 80 + 0.000 0.099 8.946
ENSG00000120948 E002 0.0000000       1 11012424 11012424 1 +      
ENSG00000120948 E003 0.0000000       1 11012425 11012428 4 +      
ENSG00000120948 E004 0.0000000       1 11012429 11012480 52 +      
ENSG00000120948 E005 0.0000000       1 11012481 11012606 126 +      
ENSG00000120948 E006 0.0000000       1 11012622 11012652 31 +      
ENSG00000120948 E007 0.0000000       1 11012653 11012653 1 +      
ENSG00000120948 E008 0.0000000       1 11012654 11012658 5 +      
ENSG00000120948 E009 1.2227459 0.0239685017 8.897766e-01 9.632796e-01 1 11012659 11012661 3 + 0.336 0.358 0.135
ENSG00000120948 E010 6.0705093 0.0722171644 4.544765e-01 7.271354e-01 1 11012662 11012669 8 + 0.903 0.787 -0.448
ENSG00000120948 E011 23.3859264 0.0005823375 5.874213e-01 8.169250e-01 1 11012670 11012743 74 + 1.370 1.404 0.120
ENSG00000120948 E012 16.8162818 0.0008057336 2.658539e-01 5.593137e-01 1 11013716 11013727 12 + 1.209 1.289 0.282
ENSG00000120948 E013 60.1456306 0.0009541882 9.330957e-01 9.806615e-01 1 11013728 11013965 238 + 1.787 1.785 -0.006
ENSG00000120948 E014 0.9893297 0.0610379588 4.277125e-01 7.062934e-01 1 11015524 11015646 123 + 0.231 0.358 0.872
ENSG00000120948 E015 0.3618970 0.0166150104 6.407291e-01   1 11016123 11016254 132 + 0.166 0.099 -0.865
ENSG00000120948 E016 18.3406393 0.0007870630 9.536541e-01 9.885787e-01 1 11016844 11016858 15 + 1.284 1.289 0.019
ENSG00000120948 E017 16.2491156 0.0085453219 8.239595e-01 9.361565e-01 1 11016859 11016864 6 + 1.245 1.228 -0.061
ENSG00000120948 E018 18.4017460 0.0015962076 3.295552e-01 6.219550e-01 1 11016865 11016877 13 + 1.319 1.254 -0.230
ENSG00000120948 E019 41.6481859 0.0022197412 5.538159e-01 7.968176e-01 1 11016878 11016965 88 + 1.643 1.616 -0.094
ENSG00000120948 E020 29.6259798 0.0009204454 2.021782e-01 4.846130e-01 1 11016966 11017007 42 + 1.519 1.450 -0.235
ENSG00000120948 E021 0.0000000       1 11018374 11018453 80 +      
ENSG00000120948 E022 32.6211911 0.0004271767 3.738109e-02 1.862459e-01 1 11018733 11018779 47 + 1.576 1.469 -0.365
ENSG00000120948 E023 37.8498237 0.0003657360 2.606661e-02 1.493072e-01 1 11018780 11018852 73 + 1.639 1.533 -0.362
ENSG00000120948 E024 23.1225532 0.0006138499 8.869223e-02 3.089734e-01 1 11018853 11018873 21 + 1.430 1.328 -0.356
ENSG00000120948 E025 0.2346346 0.0156476203 2.744937e-01   1 11018874 11019186 313 + 0.166 0.000 -13.075
ENSG00000120948 E026 18.7353858 0.0009760225 9.089904e-02 3.130687e-01 1 11020429 11020432 4 + 1.347 1.234 -0.396
ENSG00000120948 E027 37.5344767 0.0003877245 9.416958e-01 9.835583e-01 1 11020433 11020505 73 + 1.587 1.585 -0.006
ENSG00000120948 E028 27.8101567 0.0004858691 4.609403e-01 7.320050e-01 1 11020506 11020586 81 + 1.438 1.481 0.148
ENSG00000120948 E029 4.2556341 0.0036993688 3.622278e-01 6.514086e-01 1 11020587 11020599 13 + 0.771 0.662 -0.450
ENSG00000120948 E030 0.0000000       1 11022124 11022143 20 +      
ENSG00000120948 E031 0.0000000       1 11022144 11022177 34 +      
ENSG00000120948 E032 10.9230379 0.0012365953 5.866537e-02 2.427169e-01 1 11022178 11022241 64 + 1.149 0.988 -0.585
ENSG00000120948 E033 12.3872412 0.0010944577 5.484306e-02 2.332563e-01 1 11022242 11022250 9 + 1.196 1.042 -0.557
ENSG00000120948 E034 14.6847854 0.0009323978 2.006182e-02 1.272060e-01 1 11022251 11022268 18 + 1.273 1.098 -0.621
ENSG00000120948 E035 21.2932463 0.0027737338 6.901828e-02 2.654495e-01 1 11022269 11022307 39 + 1.403 1.284 -0.416
ENSG00000120948 E036 64.4389207 0.0011326898 9.830448e-01 9.986903e-01 1 11022308 11022547 240 + 1.814 1.817 0.009
ENSG00000120948 E037 56.1454531 0.0011760131 7.373807e-01 8.958776e-01 1 11022548 11022715 168 + 1.749 1.765 0.053
ENSG00000120948 E038 68.6998635 0.0002513626 1.971406e-02 1.257651e-01 1 11022716 11022817 102 + 1.882 1.800 -0.277
ENSG00000120948 E039 116.0771017 0.0001535545 1.447217e-02 1.025679e-01 1 11022818 11023044 227 + 2.099 2.034 -0.218
ENSG00000120948 E040 63.5675117 0.0008395314 9.747400e-01 9.954114e-01 1 11023045 11023155 111 + 1.810 1.810 0.002
ENSG00000120948 E041 28.2352190 0.0005076482 9.642127e-01 9.924399e-01 1 11023156 11023160 5 + 1.466 1.466 -0.003
ENSG00000120948 E042 35.3503507 0.0004169556 8.188255e-01 9.339847e-01 1 11023161 11023192 32 + 1.554 1.567 0.045
ENSG00000120948 E043 21.5535564 0.0006403730 5.561251e-01 7.985345e-01 1 11023193 11023197 5 + 1.334 1.372 0.135
ENSG00000120948 E044 42.0229841 0.0003368333 7.197924e-01 8.870598e-01 1 11023198 11023262 65 + 1.641 1.626 -0.050
ENSG00000120948 E045 45.2881604 0.0004374409 4.539220e-01 7.266363e-01 1 11023263 11023322 60 + 1.681 1.649 -0.107
ENSG00000120948 E046 29.7993899 0.0052651913 7.639256e-01 9.080435e-01 1 11023323 11023329 7 + 1.496 1.481 -0.055
ENSG00000120948 E047 204.4783602 0.0007849206 6.961190e-01 8.760405e-01 1 11023330 11023667 338 + 2.316 2.309 -0.022
ENSG00000120948 E048 84.0949632 0.0002353974 2.438772e-01 5.339012e-01 1 11023668 11023866 199 + 1.947 1.911 -0.121
ENSG00000120948 E049 29.7927275 0.0004443161 5.607222e-01 8.012137e-01 1 11023867 11023928 62 + 1.503 1.473 -0.102
ENSG00000120948 E050 19.3134674 0.0007726512 3.922450e-02 1.917808e-01 1 11023929 11024063 135 + 1.233 1.372 0.486
ENSG00000120948 E051 13.2970068 0.0074585712 1.768406e-05 5.554875e-04 1 11024064 11024301 238 + 0.928 1.306 1.364
ENSG00000120948 E052 3.2443653 0.0313640965 5.509744e-03 5.310267e-02 1 11024302 11024335 34 + 0.380 0.787 1.872
ENSG00000120948 E053 16.0256278 0.0019360772 8.005337e-07 3.814133e-05 1 11024336 11024792 457 + 1.005 1.382 1.341
ENSG00000120948 E054 14.6498848 0.0009351289 5.576592e-06 2.067136e-04 1 11024793 11025109 317 + 0.984 1.338 1.265
ENSG00000120948 E055 7.4146535 0.0019252864 3.265206e-02 1.712757e-01 1 11025110 11025208 99 + 0.804 1.021 0.821
ENSG00000120948 E056 10.1348790 0.0015506314 2.538034e-09 2.010078e-07 1 11025209 11025550 342 + 0.676 1.247 2.157
ENSG00000120948 E057 3.2461963 0.0044457397 2.656771e-03 3.148546e-02 1 11025551 11025739 189 + 0.380 0.787 1.872
ENSG00000120948 E058 1.8504955 0.0448700732 3.911911e-01 6.763722e-01 1 11029659 11029686 28 + 0.380 0.520 0.720
ENSG00000120948 E059 2.8387636 0.1281943452 4.381859e-01 7.144015e-01 1 11029687 11029757 71 + 0.492 0.662 0.772
ENSG00000120948 E060 2.1385369 0.0063753330 4.849125e-04 8.527313e-03 1 11029758 11029781 24 + 0.166 0.685 3.042
ENSG00000120948 E061 5.0230838 0.0028111855 1.137721e-06 5.217844e-05 1 11029782 11029901 120 + 0.380 0.988 2.637
ENSG00000120948 E062 12.7481671 0.0018650309 1.607364e-09 1.321518e-07 1 11029902 11030178 277 + 0.804 1.328 1.915
ENSG00000120948 E063 7.0068201 0.0146557447 1.496708e-05 4.836634e-04 1 11030179 11030528 350 + 0.580 1.089 2.009

Help

Please Click HERE to learn more details about the results from DEXseq.