ENSG00000120992

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000316963 ENSG00000120992 No_inf pgKDN_inf LYPLA1 protein_coding protein_coding 87.48325 75.85293 109.0522 1.76526 2.827651 0.5236844 24.679654 10.422092 37.880855 4.069582 3.351405 1.8608212 0.2725250 0.137050 0.34635 0.209300 0.38443352 0.001689605 FALSE  
ENST00000520718 ENSG00000120992 No_inf pgKDN_inf LYPLA1 protein_coding protein_coding_CDS_not_defined 87.48325 75.85293 109.0522 1.76526 2.827651 0.5236844 4.367972 4.018805 2.790599 1.008746 1.311840 -0.5246164 0.0530000 0.052375 0.02555 -0.026825 0.63230992 0.001689605    
ENST00000618914 ENSG00000120992 No_inf pgKDN_inf LYPLA1 protein_coding protein_coding 87.48325 75.85293 109.0522 1.76526 2.827651 0.5236844 4.147769 6.829298 0.000000 2.587526 0.000000 -9.4177044 0.0534500 0.091100 0.00000 -0.091100 0.00736086 0.001689605 FALSE  
MSTRG.27677.5 ENSG00000120992 No_inf pgKDN_inf LYPLA1 protein_coding   87.48325 75.85293 109.0522 1.76526 2.827651 0.5236844 45.689978 46.749951 57.229604 2.777040 3.333568 0.2917403 0.5228833 0.616125 0.52455 -0.091575 0.47355481 0.001689605 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000120992 E001 0.2447669 1.647191e-02 8.167378e-01   8 54046367 54046367 1 - 0.083 0.109 0.430
ENSG00000120992 E002 0.2447669 1.647191e-02 8.167378e-01   8 54046368 54046376 9 - 0.083 0.109 0.430
ENSG00000120992 E003 1.4623752 3.270556e-02 9.578301e-01 0.9899059421 8 54046377 54046377 1 - 0.394 0.384 -0.056
ENSG00000120992 E004 420.4198694 6.291269e-05 1.035045e-04 0.0024433557 8 54046378 54047406 1029 - 2.601 2.646 0.150
ENSG00000120992 E005 137.7051215 7.034982e-04 2.262940e-01 0.5143325587 8 54047407 54047791 385 - 2.153 2.121 -0.106
ENSG00000120992 E006 66.7826789 3.295983e-04 3.434846e-01 0.6346739556 8 54047792 54047962 171 - 1.844 1.809 -0.118
ENSG00000120992 E007 63.4388385 2.363283e-03 1.857781e-01 0.4637059182 8 54047963 54048118 156 - 1.830 1.775 -0.187
ENSG00000120992 E008 0.2444846 1.645910e-02 8.165410e-01   8 54051011 54051011 1 - 0.083 0.109 0.430
ENSG00000120992 E009 48.6286877 3.262038e-04 2.453446e-01 0.5358120828 8 54051012 54051071 60 - 1.715 1.664 -0.170
ENSG00000120992 E010 29.9960768 8.737095e-03 2.882812e-01 0.5818683148 8 54051072 54051124 53 - 1.519 1.447 -0.248
ENSG00000120992 E011 15.6785107 7.589181e-03 5.224345e-01 0.7759529822 8 54051125 54051146 22 - 1.242 1.190 -0.183
ENSG00000120992 E012 13.8641552 9.749797e-04 6.297148e-01 0.8411825946 8 54051147 54051188 42 - 1.186 1.148 -0.134
ENSG00000120992 E013 0.3544103 3.921262e-02 1.783220e-01   8 54052654 54052654 1 - 0.213 0.000 -11.955
ENSG00000120992 E014 33.0590189 4.491853e-04 3.324597e-01 0.6245373405 8 54052655 54052741 87 - 1.551 1.501 -0.173
ENSG00000120992 E015 18.2632398 7.536828e-04 8.828002e-01 0.9605607203 8 54052742 54052756 15 - 1.287 1.276 -0.036
ENSG00000120992 E016 4.1002467 1.342592e-02 2.830613e-03 0.0330589563 8 54052757 54052898 142 - 0.493 0.877 1.631
ENSG00000120992 E017 9.3168356 1.667692e-03 3.798727e-06 0.0001481421 8 54053198 54053668 471 - 0.767 1.198 1.607
ENSG00000120992 E018 7.9178504 6.063828e-02 2.312442e-02 0.1387006689 8 54054453 54055059 607 - 0.783 1.092 1.166
ENSG00000120992 E019 22.4817932 6.685917e-04 2.016343e-01 0.4840160787 8 54055060 54055101 42 - 1.332 1.410 0.273
ENSG00000120992 E020 18.6934523 8.695794e-03 3.440737e-01 0.6353797530 8 54055102 54055133 32 - 1.323 1.249 -0.257
ENSG00000120992 E021 33.1462176 9.306030e-04 1.704586e-01 0.4426341808 8 54062254 54062324 71 - 1.561 1.489 -0.248
ENSG00000120992 E022 31.6659924 5.089103e-04 9.247461e-01 0.9771507457 8 54063328 54063375 48 - 1.514 1.509 -0.018
ENSG00000120992 E023 29.0598967 1.148677e-03 4.526790e-01 0.7257459220 8 54065748 54065813 66 - 1.494 1.451 -0.145
ENSG00000120992 E024 0.2451451 1.638261e-02 8.165041e-01   8 54081961 54081998 38 - 0.083 0.109 0.430
ENSG00000120992 E025 0.1265070 1.229599e-02 3.970854e-01   8 54100224 54100347 124 - 0.000 0.109 10.373
ENSG00000120992 E026 0.2447669 1.647191e-02 8.167378e-01   8 54100350 54100907 558 - 0.083 0.109 0.430
ENSG00000120992 E027 18.4172569 7.292263e-04 7.672628e-02 0.2832221826 8 54100908 54100939 32 - 1.336 1.213 -0.430
ENSG00000120992 E028 1.5856441 8.399379e-03 7.983872e-01 0.9241928796 8 54101350 54101754 405 - 0.394 0.432 0.208
ENSG00000120992 E029 20.1617895 6.923600e-04 1.401818e-03 0.0194159394 8 54101755 54102017 263 - 1.406 1.190 -0.756

Help

Please Click HERE to learn more details about the results from DEXseq.