ENSG00000121064

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262288 ENSG00000121064 No_inf pgKDN_inf SCPEP1 protein_coding protein_coding 270.0431 244.1668 293.3715 1.273283 3.889723 0.264852 180.23538 143.19687 202.73140 2.258199 3.727019 0.5015400 0.66409167 0.586525 0.691175 0.104650 0.003617973 0.003617973 FALSE TRUE
ENST00000570479 ENSG00000121064 No_inf pgKDN_inf SCPEP1 protein_coding retained_intron 270.0431 244.1668 293.3715 1.273283 3.889723 0.264852 17.89612 28.41819 10.35597 8.936593 2.524870 -1.4554678 0.06869167 0.116375 0.035125 -0.081250 0.194576817 0.003617973 FALSE TRUE
ENST00000573239 ENSG00000121064 No_inf pgKDN_inf SCPEP1 protein_coding protein_coding 270.0431 244.1668 293.3715 1.273283 3.889723 0.264852 29.28102 28.62763 36.71055 10.761769 3.451221 0.3586757 0.10825833 0.117350 0.124850 0.007500 0.914863141 0.003617973 FALSE TRUE
MSTRG.12969.1 ENSG00000121064 No_inf pgKDN_inf SCPEP1 protein_coding   270.0431 244.1668 293.3715 1.273283 3.889723 0.264852 23.79877 18.21670 30.34537 3.947997 1.390557 0.7358982 0.08733333 0.074475 0.103650 0.029175 0.600869853 0.003617973 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000121064 E001 4.3472330 3.233858e-03 6.160873e-02 0.2494363385 17 56978107 56978128 22 + 0.822 0.593 -0.951
ENSG00000121064 E002 4.7093822 3.010081e-03 5.511974e-02 0.2338599810 17 56978129 56978130 2 + 0.851 0.622 -0.937
ENSG00000121064 E003 5.5539864 2.499173e-03 3.312193e-02 0.1729162746 17 56978131 56978133 3 + 0.915 0.673 -0.959
ENSG00000121064 E004 6.9259585 2.015386e-03 2.642157e-01 0.5572773074 17 56978134 56978136 3 + 0.949 0.835 -0.437
ENSG00000121064 E005 12.5782873 1.047568e-02 8.462612e-03 0.0718228647 17 56978137 56978147 11 + 1.231 0.989 -0.872
ENSG00000121064 E006 15.4634475 1.083703e-02 1.900185e-03 0.0246061445 17 56978148 56978152 5 + 1.324 1.055 -0.957
ENSG00000121064 E007 20.1757609 2.407484e-03 1.717037e-04 0.0036909795 17 56978153 56978159 7 + 1.431 1.170 -0.912
ENSG00000121064 E008 59.1206902 2.592799e-04 3.743805e-04 0.0069316307 17 56978160 56978235 76 + 1.840 1.700 -0.474
ENSG00000121064 E009 50.1791010 2.844497e-04 5.682130e-03 0.0542736346 17 56981082 56981116 35 + 1.761 1.643 -0.398
ENSG00000121064 E010 103.4288598 1.594376e-04 3.608153e-03 0.0395854580 17 56981117 56981230 114 + 2.057 1.971 -0.288
ENSG00000121064 E011 86.6709443 1.881922e-04 2.114379e-02 0.1315001413 17 56985378 56985427 50 + 1.976 1.902 -0.249
ENSG00000121064 E012 84.5798866 4.513021e-04 2.139859e-02 0.1324679684 17 56985428 56985467 40 + 1.967 1.890 -0.257
ENSG00000121064 E013 1.2608854 9.927320e-03 3.598171e-03 0.0395000490 17 56987090 56987240 151 + 0.088 0.530 3.403
ENSG00000121064 E014 0.6253605 1.718387e-01 1.750581e-01 0.4489150767 17 56987241 56987332 92 + 0.088 0.314 2.232
ENSG00000121064 E015 0.8797592 2.067423e-02 3.182514e-02 0.1685998520 17 56987333 56987561 229 + 0.088 0.414 2.818
ENSG00000121064 E016 0.7532522 1.422110e-02 6.215135e-02 0.2503780021 17 56987562 56987694 133 + 0.088 0.367 2.555
ENSG00000121064 E017 113.5772909 6.071143e-04 9.085961e-02 0.3130627674 17 56987695 56987751 57 + 2.082 2.032 -0.166
ENSG00000121064 E018 146.7107349 7.390523e-04 7.734362e-01 0.9128699987 17 56987752 56987850 99 + 2.165 2.173 0.029
ENSG00000121064 E019 120.6896154 1.417573e-04 3.325139e-02 0.1733567460 17 56988216 56988290 75 + 2.056 2.115 0.198
ENSG00000121064 E020 156.4267447 1.223734e-04 1.545345e-02 0.1072948696 17 56991099 56991171 73 + 2.168 2.226 0.197
ENSG00000121064 E021 0.3722815 1.662864e-02 4.896527e-01   17 56994905 56994980 76 + 0.088 0.185 1.233
ENSG00000121064 E022 120.7105369 3.797514e-04 4.791229e-01 0.7449984491 17 56994981 56995018 38 + 2.075 2.096 0.070
ENSG00000121064 E023 1.1983203 1.006920e-02 8.880262e-02 0.3091583219 17 56995019 56995446 428 + 0.448 0.185 -1.767
ENSG00000121064 E024 0.1268540 1.233634e-02 4.585061e-01   17 56995447 56995506 60 + 0.000 0.102 9.022
ENSG00000121064 E025 132.0862676 2.558097e-04 9.577812e-01 0.9899059421 17 56995507 56995559 53 + 2.124 2.123 -0.002
ENSG00000121064 E026 184.0003402 9.407404e-05 4.959835e-01 0.7570191366 17 56995560 56995635 76 + 2.259 2.275 0.053
ENSG00000121064 E027 1.9604784 3.034992e-02 7.695168e-01 0.9109545328 17 56995636 56995875 240 + 0.448 0.495 0.233
ENSG00000121064 E028 150.1584370 7.889983e-04 2.074026e-01 0.4910179163 17 56996962 56997013 52 + 2.162 2.197 0.116
ENSG00000121064 E029 135.3908110 2.202671e-03 7.887736e-01 0.9189268091 17 56997014 56997055 42 + 2.138 2.130 -0.025
ENSG00000121064 E030 6.1661025 3.556459e-03 5.222376e-02 0.2269366660 17 56997056 56997135 80 + 0.742 0.952 0.818
ENSG00000121064 E031 14.9924881 9.216872e-04 2.488073e-05 0.0007434445 17 56997968 56998290 323 + 1.020 1.342 1.145
ENSG00000121064 E032 7.3528568 2.267661e-02 1.182999e-04 0.0027289934 17 56998291 56998373 83 + 0.642 1.103 1.785
ENSG00000121064 E033 4.1975405 2.602640e-02 1.005737e-01 0.3311362500 17 56998374 56998384 11 + 0.595 0.818 0.925
ENSG00000121064 E034 202.4156712 9.096222e-05 3.074001e-01 0.6006166297 17 56998385 56998498 114 + 2.318 2.297 -0.069
ENSG00000121064 E035 286.5854402 1.363024e-03 7.318778e-01 0.8933865268 17 57000855 57000992 138 + 2.454 2.463 0.029
ENSG00000121064 E036 354.4590263 7.172450e-04 1.445092e-01 0.4047298643 17 57002018 57002181 164 + 2.537 2.565 0.092
ENSG00000121064 E037 636.5731555 4.431180e-05 7.341962e-02 0.2755227991 17 57006173 57006768 596 + 2.794 2.815 0.069

Help

Please Click HERE to learn more details about the results from DEXseq.