ENSG00000121281

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000254235 ENSG00000121281 No_inf pgKDN_inf ADCY7 protein_coding protein_coding 22.11894 24.71753 20.73026 0.7418507 1.340776 -0.2536838 2.9330314 0.000000 3.640879 0.0000000 2.331883 8.51210013 0.1337167 0.000000 0.160225 0.160225 4.335495e-01 7.97948e-06 FALSE TRUE
ENST00000568930 ENSG00000121281 No_inf pgKDN_inf ADCY7 protein_coding retained_intron 22.11894 24.71753 20.73026 0.7418507 1.340776 -0.2536838 1.4433792 3.933288 0.000000 0.7877725 0.000000 -8.62325525 0.0597000 0.159800 0.000000 -0.159800 7.979480e-06 7.97948e-06 FALSE FALSE
ENST00000673801 ENSG00000121281 No_inf pgKDN_inf ADCY7 protein_coding protein_coding 22.11894 24.71753 20.73026 0.7418507 1.340776 -0.2536838 3.1549570 3.872128 4.479639 1.8983804 1.748302 0.20975195 0.1477917 0.161650 0.230100 0.068450 8.883576e-01 7.97948e-06 FALSE TRUE
MSTRG.11163.11 ENSG00000121281 No_inf pgKDN_inf ADCY7 protein_coding   22.11894 24.71753 20.73026 0.7418507 1.340776 -0.2536838 2.8461497 3.018629 1.635294 1.7752920 1.635294 -0.88031973 0.1344417 0.116700 0.086700 -0.030000 8.259075e-01 7.97948e-06 FALSE TRUE
MSTRG.11163.18 ENSG00000121281 No_inf pgKDN_inf ADCY7 protein_coding   22.11894 24.71753 20.73026 0.7418507 1.340776 -0.2536838 7.4576740 7.856896 7.560254 0.8383838 1.253754 -0.05545284 0.3395917 0.318925 0.367525 0.048600 8.967271e-01 7.97948e-06 TRUE TRUE
MSTRG.11163.6 ENSG00000121281 No_inf pgKDN_inf ADCY7 protein_coding   22.11894 24.71753 20.73026 0.7418507 1.340776 -0.2536838 0.7594236 1.268668 0.000000 0.9971916 0.000000 -6.99849838 0.0330750 0.054850 0.000000 -0.054850 5.866503e-01 7.97948e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000121281 E001 0.1170040 0.0118156870 0.454429435   16 50246137 50246147 11 + 0.102 0.000 -12.781
ENSG00000121281 E002 0.1170040 0.0118156870 0.454429435   16 50246148 50246203 56 + 0.102 0.000 -12.783
ENSG00000121281 E003 0.0000000       16 50266551 50266563 13 +      
ENSG00000121281 E004 0.3631878 0.0165312212 0.485413662   16 50266564 50266587 24 + 0.185 0.088 -1.239
ENSG00000121281 E005 1.3595399 0.1056266679 0.576350411 0.810489082 16 50266588 50266680 93 + 0.315 0.411 0.568
ENSG00000121281 E006 0.2363338 0.0156255641 0.190327867   16 50274131 50274152 22 + 0.185 0.000 -13.783
ENSG00000121281 E007 0.2363338 0.0156255641 0.190327867   16 50274153 50274156 4 + 0.185 0.000 -13.783
ENSG00000121281 E008 0.2363338 0.0156255641 0.190327867   16 50274157 50274161 5 + 0.185 0.000 -13.783
ENSG00000121281 E009 0.6093096 0.1976944732 0.575043760 0.809691159 16 50274162 50274198 37 + 0.255 0.162 -0.824
ENSG00000121281 E010 0.2458395 0.0164177134 0.897269170   16 50279527 50279550 24 + 0.102 0.088 -0.239
ENSG00000121281 E011 0.4831157 0.0339430069 0.249651795   16 50279551 50279704 154 + 0.255 0.088 -1.824
ENSG00000121281 E012 0.2533610 0.0160561978 0.305160233   16 50287882 50287910 29 + 0.000 0.162 13.200
ENSG00000121281 E013 0.2533610 0.0160561978 0.305160233   16 50287911 50287911 1 + 0.000 0.162 13.200
ENSG00000121281 E014 10.2086497 0.0221245279 0.846854387 0.945656111 16 50287912 50288076 165 + 1.035 1.056 0.075
ENSG00000121281 E015 11.8756823 0.0011830075 0.352817884 0.642824125 16 50288077 50288350 274 + 1.147 1.072 -0.269
ENSG00000121281 E016 0.2438580 0.0164586682 0.896205733   16 50289221 50289313 93 + 0.102 0.088 -0.239
ENSG00000121281 E017 11.1965807 0.0013243535 0.013075922 0.095768168 16 50290457 50290660 204 + 1.186 0.981 -0.746
ENSG00000121281 E018 6.0821370 0.0282853531 0.077438770 0.284702292 16 50291736 50291788 53 + 0.953 0.741 -0.824
ENSG00000121281 E019 7.5749227 0.0642368687 0.252772073 0.544121640 16 50291789 50291897 109 + 1.002 0.864 -0.519
ENSG00000121281 E020 12.7341798 0.0015949864 0.293867076 0.587308856 16 50292676 50292825 150 + 1.179 1.097 -0.295
ENSG00000121281 E021 13.0433444 0.0013866286 0.611765467 0.831065492 16 50293354 50293502 149 + 1.122 1.162 0.144
ENSG00000121281 E022 3.7279982 0.0126542872 0.086871646 0.305527828 16 50294640 50294663 24 + 0.531 0.758 0.983
ENSG00000121281 E023 7.1067288 0.0020979511 0.525954605 0.778517321 16 50294664 50294751 88 + 0.940 0.877 -0.239
ENSG00000121281 E024 11.9688240 0.0125880381 0.139701759 0.397524253 16 50298904 50299031 128 + 1.179 1.047 -0.475
ENSG00000121281 E025 11.9304977 0.0033976065 0.764689935 0.908508575 16 50300715 50300819 105 + 1.095 1.119 0.090
ENSG00000121281 E026 9.2044751 0.0122589747 0.742840070 0.898363933 16 50300820 50300873 54 + 1.024 0.991 -0.124
ENSG00000121281 E027 7.9690789 0.0027912929 0.586964156 0.816880049 16 50301082 50301124 43 + 0.978 0.926 -0.195
ENSG00000121281 E028 10.8934334 0.0013330397 0.369886674 0.658159343 16 50301125 50301214 90 + 1.113 1.038 -0.271
ENSG00000121281 E029 1.2440452 0.0107585754 0.311987209 0.605364734 16 50301668 50301964 297 + 0.255 0.411 0.983
ENSG00000121281 E030 6.3346535 0.0025299198 0.153498322 0.418141246 16 50304360 50304393 34 + 0.940 0.791 -0.573
ENSG00000121281 E031 10.8826588 0.0014884947 0.268325849 0.561840451 16 50304394 50304516 123 + 1.122 1.029 -0.336
ENSG00000121281 E032 7.8755195 0.0017772552 0.738246234 0.896103626 16 50304517 50304551 35 + 0.927 0.960 0.124
ENSG00000121281 E033 8.8356842 0.0016547257 0.811715405 0.930707718 16 50304925 50304959 35 + 1.002 0.981 -0.078
ENSG00000121281 E034 9.3634016 0.0017413019 0.514797236 0.771182258 16 50305503 50305586 84 + 0.978 1.038 0.220
ENSG00000121281 E035 7.5975839 0.0026193194 0.512638443 0.769621205 16 50305777 50305849 73 + 0.966 0.902 -0.239
ENSG00000121281 E036 9.7359644 0.0014882979 0.466523409 0.735178212 16 50307050 50307147 98 + 0.990 1.056 0.240
ENSG00000121281 E037 11.0937042 0.0013771988 0.364810732 0.653327079 16 50308327 50308411 85 + 1.035 1.112 0.280
ENSG00000121281 E038 1.7510852 0.3649512280 0.184867812 0.462375283 16 50308412 50308666 255 + 0.255 0.541 1.633
ENSG00000121281 E039 17.9804191 0.0012078604 0.409350299 0.691555178 16 50308667 50308792 126 + 1.243 1.299 0.199
ENSG00000121281 E040 0.8798238 0.0124078895 0.079024559 0.288287403 16 50308793 50309198 406 + 0.102 0.371 2.346
ENSG00000121281 E041 14.3295218 0.0009331375 0.082477004 0.295824616 16 50309548 50309646 99 + 1.104 1.236 0.472
ENSG00000121281 E042 1.0881153 0.0109381590 0.212591689 0.497739197 16 50310454 50310529 76 + 0.414 0.224 -1.239
ENSG00000121281 E043 19.9575062 0.0007910686 0.315606738 0.608469483 16 50310687 50310880 194 + 1.281 1.346 0.228
ENSG00000121281 E044 13.8965349 0.0017665457 0.598223581 0.823832873 16 50311693 50311786 94 + 1.147 1.188 0.146
ENSG00000121281 E045 18.6806757 0.0122745518 0.712890480 0.884048449 16 50312036 50312191 156 + 1.274 1.304 0.105
ENSG00000121281 E046 12.2765321 0.0011612385 0.005914369 0.055923135 16 50312890 50313036 147 + 0.978 1.207 0.827
ENSG00000121281 E047 1.3956697 0.0095429125 0.000585536 0.009878104 16 50313104 50313957 854 + 0.000 0.541 15.659
ENSG00000121281 E048 0.0000000       16 50313958 50314062 105 +      
ENSG00000121281 E049 0.0000000       16 50314292 50314406 115 +      
ENSG00000121281 E050 0.0000000       16 50315014 50315138 125 +      
ENSG00000121281 E051 0.0000000       16 50315359 50318135 2777 +      

Help

Please Click HERE to learn more details about the results from DEXseq.