ENSG00000121310

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358358 ENSG00000121310 No_inf pgKDN_inf ECHDC2 protein_coding protein_coding 29.619 51.92307 18.68523 4.359554 2.343574 -1.473983 1.132210 0.2895928 1.0671464 0.2895928 0.3803197 1.846139 0.05480833 0.005275 0.053575 0.048300 0.2076017600 0.0007746308 FALSE TRUE
ENST00000460612 ENSG00000121310 No_inf pgKDN_inf ECHDC2 protein_coding retained_intron 29.619 51.92307 18.68523 4.359554 2.343574 -1.473983 3.234848 6.5763475 2.2789854 2.2674935 0.2869263 -1.524770 0.09825000 0.118350 0.131900 0.013550 0.9139377273 0.0007746308 TRUE TRUE
ENST00000487040 ENSG00000121310 No_inf pgKDN_inf ECHDC2 protein_coding retained_intron 29.619 51.92307 18.68523 4.359554 2.343574 -1.473983 3.092944 5.6444811 1.7431066 1.2798627 0.6561730 -1.689481 0.10308333 0.115925 0.095350 -0.020575 0.8964356105 0.0007746308   FALSE
ENST00000498544 ENSG00000121310 No_inf pgKDN_inf ECHDC2 protein_coding retained_intron 29.619 51.92307 18.68523 4.359554 2.343574 -1.473983 3.306127 5.3796400 2.5100667 0.3498534 0.5756802 -1.096727 0.11966667 0.106300 0.135100 0.028800 0.8742924397 0.0007746308   FALSE
ENST00000543419 ENSG00000121310 No_inf pgKDN_inf ECHDC2 protein_coding protein_coding_CDS_not_defined 29.619 51.92307 18.68523 4.359554 2.343574 -1.473983 5.564022 10.9481897 4.3985858 4.6764111 1.5984688 -1.313622 0.15851667 0.191775 0.224700 0.032925 0.9723252420 0.0007746308   FALSE
MSTRG.1034.1 ENSG00000121310 No_inf pgKDN_inf ECHDC2 protein_coding   29.619 51.92307 18.68523 4.359554 2.343574 -1.473983 2.513593 5.1020704 1.7252034 1.1454039 0.2124908 -1.558803 0.07575833 0.094900 0.099150 0.004250 1.0000000000 0.0007746308 FALSE TRUE
MSTRG.1034.4 ENSG00000121310 No_inf pgKDN_inf ECHDC2 protein_coding   29.619 51.92307 18.68523 4.359554 2.343574 -1.473983 2.335255 4.7685023 0.3219774 1.0969316 0.2257491 -3.847401 0.07708333 0.099675 0.014975 -0.084700 0.1658051328 0.0007746308 TRUE FALSE
MSTRG.1034.5 ENSG00000121310 No_inf pgKDN_inf ECHDC2 protein_coding   29.619 51.92307 18.68523 4.359554 2.343574 -1.473983 2.212239 5.1605833 0.0000000 1.2945894 0.0000000 -9.014183 0.06515833 0.107700 0.000000 -0.107700 0.0007746308 0.0007746308 TRUE FALSE
MSTRG.1034.8 ENSG00000121310 No_inf pgKDN_inf ECHDC2 protein_coding   29.619 51.92307 18.68523 4.359554 2.343574 -1.473983 1.907128 3.6434489 0.6865119 0.3956975 0.1290220 -2.391039 0.06314167 0.072125 0.040025 -0.032100 0.7241227418 0.0007746308 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000121310 E001 0.1265070 0.0123362011 9.624470e-01   1 52895883 52895909 27 - 0.000 0.047 8.083
ENSG00000121310 E002 0.6152282 0.3029803967 2.620195e-01 5.547304e-01 1 52895910 52895983 74 - 0.311 0.128 -1.604
ENSG00000121310 E003 0.7423645 0.0918693682 3.820385e-01 6.683119e-01 1 52895984 52895986 3 - 0.311 0.164 -1.188
ENSG00000121310 E004 2.7561504 0.1294719324 9.177964e-01 9.741146e-01 1 52895987 52896222 236 - 0.490 0.486 -0.018
ENSG00000121310 E005 1.1425910 0.0349753278 1.548671e-01 4.204260e-01 1 52896223 52896224 2 - 0.000 0.308 13.290
ENSG00000121310 E006 1.1425910 0.0349753278 1.548671e-01 4.204260e-01 1 52896225 52896231 7 - 0.000 0.308 13.290
ENSG00000121310 E007 1.0153287 0.0974438868 2.226548e-01 5.099653e-01 1 52896232 52896232 1 - 0.000 0.283 13.029
ENSG00000121310 E008 1.0153287 0.0974438868 2.226548e-01 5.099653e-01 1 52896233 52896238 6 - 0.000 0.283 13.029
ENSG00000121310 E009 1.2698533 0.0238379591 1.183190e-01 3.633650e-01 1 52896239 52896249 11 - 0.000 0.332 13.442
ENSG00000121310 E010 18.3219817 0.0214666660 6.651496e-01 8.607462e-01 1 52896250 52896402 153 - 1.132 1.176 0.158
ENSG00000121310 E011 35.6289645 0.0020261692 1.569913e-01 4.233372e-01 1 52896403 52896547 145 - 1.517 1.426 -0.311
ENSG00000121310 E012 22.8862243 0.0045355421 3.709959e-01 6.590824e-01 1 52896548 52896597 50 - 1.319 1.246 -0.256
ENSG00000121310 E013 2.8735367 0.0059848827 6.593721e-01 8.578597e-01 1 52896598 52897436 839 - 0.558 0.486 -0.340
ENSG00000121310 E014 15.1156427 0.0012735547 2.396268e-01 5.286873e-01 1 52897437 52897484 48 - 1.179 1.071 -0.388
ENSG00000121310 E015 13.4092933 0.0340174773 9.693751e-01 9.936887e-01 1 52897485 52899173 1689 - 1.038 1.045 0.024
ENSG00000121310 E016 10.2543435 0.0026977734 5.450042e-01 7.911140e-01 1 52899174 52899176 3 - 0.995 0.927 -0.253
ENSG00000121310 E017 17.6061891 0.0008225261 1.107401e-01 3.492966e-01 1 52899177 52899224 48 - 1.261 1.127 -0.477
ENSG00000121310 E018 7.8400373 0.0263854539 6.417806e-02 2.550977e-01 1 52899225 52902041 2817 - 1.017 0.790 -0.866
ENSG00000121310 E019 29.4021394 0.0191631268 1.055670e-02 8.324054e-02 1 52904646 52904788 143 - 1.537 1.316 -0.762
ENSG00000121310 E020 13.5155613 0.0131004584 7.234137e-04 1.164327e-02 1 52904789 52904833 45 - 1.297 0.972 -1.168
ENSG00000121310 E021 5.8663997 0.0025019221 3.617680e-01 6.511244e-01 1 52904834 52905033 200 - 0.829 0.710 -0.477
ENSG00000121310 E022 13.7911400 0.0019324028 2.981385e-03 3.438892e-02 1 52905034 52905090 57 - 1.261 0.998 -0.947
ENSG00000121310 E023 27.8869733 0.0005212148 1.378119e-01 3.950394e-01 1 52905091 52905436 346 - 1.248 1.358 0.382
ENSG00000121310 E024 77.5917221 0.0001956668 3.542898e-07 1.823308e-05 1 52905437 52906518 1082 - 1.563 1.805 0.823
ENSG00000121310 E025 14.7244482 0.0019889313 1.257540e-01 3.759653e-01 1 52906519 52906611 93 - 1.194 1.054 -0.503
ENSG00000121310 E026 15.3790469 0.0010366914 1.061357e-02 8.350920e-02 1 52906612 52907013 402 - 0.862 1.134 1.009
ENSG00000121310 E027 10.1006132 0.0014095763 1.384190e-01 3.958162e-01 1 52907014 52907311 298 - 1.059 0.903 -0.579
ENSG00000121310 E028 8.3927736 0.0018455296 7.826465e-01 9.164230e-01 1 52907312 52907447 136 - 0.892 0.857 -0.133
ENSG00000121310 E029 10.4360785 0.0021571682 2.356235e-01 5.249987e-01 1 52907448 52907598 151 - 0.829 0.966 0.523
ENSG00000121310 E030 7.5730874 0.0022882556 3.198220e-02 1.690775e-01 1 52907599 52907649 51 - 0.558 0.864 1.272
ENSG00000121310 E031 8.3136849 0.0018060205 9.259451e-02 3.160955e-01 1 52907650 52907838 189 - 0.668 0.890 0.887
ENSG00000121310 E032 1.2685333 0.0100969694 1.147177e-01 3.570011e-01 1 52907839 52907867 29 - 0.000 0.332 13.472
ENSG00000121310 E033 14.2232352 0.0161685176 1.788970e-01 4.538856e-01 1 52907868 52907954 87 - 1.179 1.040 -0.499
ENSG00000121310 E034 0.0000000       1 52911564 52911565 2 -      
ENSG00000121310 E035 8.3914499 0.0025906366 7.831250e-01 9.165837e-01 1 52911566 52911598 33 - 0.892 0.857 -0.133
ENSG00000121310 E036 4.7571102 0.0132762619 6.551523e-01 8.553712e-01 1 52911599 52911599 1 - 0.714 0.647 -0.281
ENSG00000121310 E037 8.6425792 0.0606146296 7.750043e-01 9.135413e-01 1 52911600 52911653 54 - 0.920 0.864 -0.214
ENSG00000121310 E038 0.1268540 0.0123913156 9.643886e-01   1 52911654 52911676 23 - 0.000 0.047 10.450
ENSG00000121310 E039 10.6681695 0.0014862532 6.946624e-01 8.752493e-01 1 52911723 52911790 68 - 0.920 0.961 0.154
ENSG00000121310 E040 18.6185804 0.0008799953 8.154226e-02 2.935652e-01 1 52911791 52912021 231 - 1.038 1.198 0.575
ENSG00000121310 E041 21.6934507 0.0006316827 7.955556e-01 9.223427e-01 1 52912022 52912368 347 - 1.222 1.240 0.065
ENSG00000121310 E042 17.1057779 0.0007934526 1.240030e-01 3.730675e-01 1 52912369 52912753 385 - 1.017 1.162 0.525
ENSG00000121310 E043 6.2503615 0.0022806780 4.850445e-01 7.488794e-01 1 52912754 52912849 96 - 0.829 0.738 -0.362
ENSG00000121310 E044 21.7285333 0.0007270249 2.806613e-01 5.739317e-01 1 52912850 52913419 570 - 1.164 1.252 0.311
ENSG00000121310 E045 11.9460102 0.0011884725 2.472762e-01 5.378743e-01 1 52913420 52913719 300 - 0.892 1.017 0.469
ENSG00000121310 E046 6.5418975 0.0025798128 3.694923e-01 6.576529e-01 1 52913720 52913894 175 - 0.668 0.790 0.497
ENSG00000121310 E047 11.5477732 0.0012436088 6.512641e-01 8.530853e-01 1 52913895 52914095 201 - 0.946 0.993 0.172
ENSG00000121310 E048 22.3928636 0.0007461644 5.965084e-02 2.448845e-01 1 52914096 52915130 1035 - 1.115 1.274 0.565
ENSG00000121310 E049 3.4839784 0.0040937584 1.783452e-01 4.531645e-01 1 52915131 52915292 162 - 0.714 0.518 -0.866
ENSG00000121310 E050 3.1100633 0.0047996049 2.279649e-01 5.164617e-01 1 52917544 52917615 72 - 0.668 0.486 -0.825
ENSG00000121310 E051 5.7494964 0.0232143506 5.515086e-01 7.953864e-01 1 52917616 52917802 187 - 0.794 0.710 -0.339
ENSG00000121310 E052 1.1141761 0.0132417864 2.779676e-01 5.712142e-01 1 52921398 52921482 85 - 0.409 0.227 -1.188
ENSG00000121310 E053 0.7512066 0.1649600033 1.000000e+00 1.000000e+00 1 52921483 52921552 70 - 0.183 0.197 0.134
ENSG00000121310 E054 8.7358559 0.0347165019 2.568780e-01 5.491046e-01 1 52921553 52921919 367 - 0.995 0.850 -0.548
ENSG00000121310 E055 0.0000000       1 52927109 52927212 104 -      

Help

Please Click HERE to learn more details about the results from DEXseq.