ENSG00000121350

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000240651 ENSG00000121350 No_inf pgKDN_inf PYROXD1 protein_coding protein_coding 9.13645 10.98523 9.72711 0.4699173 1.550953 -0.1753122 3.4315777 0.8856493 4.6789624 0.5783644 0.1895369 2.3882628 0.44270833 0.08090 0.516325 0.435425 0.03798104 0.01088921 FALSE TRUE
ENST00000536851 ENSG00000121350 No_inf pgKDN_inf PYROXD1 protein_coding retained_intron 9.13645 10.98523 9.72711 0.4699173 1.550953 -0.1753122 0.4618699 1.3856097 0.0000000 0.4265441 0.0000000 -7.1247518 0.04126667 0.12380 0.000000 -0.123800 0.01088921 0.01088921   FALSE
ENST00000538615 ENSG00000121350 No_inf pgKDN_inf PYROXD1 protein_coding retained_intron 9.13645 10.98523 9.72711 0.4699173 1.550953 -0.1753122 2.9522175 5.1713171 2.8669484 0.6779175 0.7245112 -0.8487795 0.28728333 0.46780 0.289650 -0.178150 0.51865982 0.01088921 FALSE TRUE
ENST00000543476 ENSG00000121350 No_inf pgKDN_inf PYROXD1 protein_coding nonsense_mediated_decay 9.13645 10.98523 9.72711 0.4699173 1.550953 -0.1753122 0.3188994 0.0000000 0.9566981 0.0000000 0.4874201 6.5949935 0.02751667 0.00000 0.082550 0.082550 0.07604961 0.01088921 TRUE TRUE
ENST00000544187 ENSG00000121350 No_inf pgKDN_inf PYROXD1 protein_coding nonsense_mediated_decay 9.13645 10.98523 9.72711 0.4699173 1.550953 -0.1753122 0.3264231 0.9792692 0.0000000 0.5786215 0.0000000 -6.6282912 0.02911667 0.08735 0.000000 -0.087350 0.52572008 0.01088921   FALSE
ENST00000544970 ENSG00000121350 No_inf pgKDN_inf PYROXD1 protein_coding nonsense_mediated_decay 9.13645 10.98523 9.72711 0.4699173 1.550953 -0.1753122 0.6977041 1.7646890 0.3284234 1.0266707 0.3284234 -2.3906650 0.07144167 0.16695 0.047375 -0.119575 0.81846666 0.01088921 FALSE TRUE
MSTRG.6147.5 ENSG00000121350 No_inf pgKDN_inf PYROXD1 protein_coding   9.13645 10.98523 9.72711 0.4699173 1.550953 -0.1753122 0.4392287 0.0000000 0.7289939 0.0000000 0.7289939 6.2074906 0.04511667 0.00000 0.052150 0.052150 0.82475794 0.01088921 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000121350 E001 0.0000000       12 21437615 21437644 30 +      
ENSG00000121350 E002 0.0000000       12 21437645 21437654 10 +      
ENSG00000121350 E003 0.3629044 0.016775812 0.714835764   12 21437655 21437704 50 + 0.150 0.111 -0.505
ENSG00000121350 E004 0.3629044 0.016775812 0.714835764   12 21437705 21437708 4 + 0.150 0.111 -0.505
ENSG00000121350 E005 1.9528243 0.007887430 0.920067288 0.97517803 12 21437709 21437814 106 + 0.456 0.482 0.132
ENSG00000121350 E006 0.2541163 0.016593041 0.180834094   12 21437915 21438538 624 + 0.000 0.199 12.142
ENSG00000121350 E007 1.7239176 0.009029877 0.366306200 0.65496481 12 21440368 21440448 81 + 0.350 0.522 0.910
ENSG00000121350 E008 0.0000000       12 21441207 21441300 94 +      
ENSG00000121350 E009 3.4891832 0.046955005 0.037588015 0.18691425 12 21445347 21445466 120 + 0.743 0.482 -1.158
ENSG00000121350 E010 2.6490232 0.005555038 0.084067619 0.29934000 12 21449563 21449691 129 + 0.633 0.438 -0.920
ENSG00000121350 E011 2.0518585 0.302281398 0.219608592 0.50624298 12 21452081 21452154 74 + 0.541 0.390 -0.767
ENSG00000121350 E012 0.6263978 0.014418373 0.112871766 0.35345334 12 21454782 21455131 350 + 0.081 0.335 2.495
ENSG00000121350 E013 3.6356536 0.031120820 0.374653022 0.66227513 12 21455132 21455241 110 + 0.692 0.623 -0.294
ENSG00000121350 E014 3.7245892 0.045015764 0.047855182 0.21522609 12 21455242 21455292 51 + 0.759 0.522 -1.029
ENSG00000121350 E015 6.0068850 0.002614348 0.001464374 0.02007116 12 21455995 21456095 101 + 0.946 0.652 -1.168
ENSG00000121350 E016 1.1008242 0.022053315 0.988204765 0.99996772 12 21456865 21457086 222 + 0.308 0.335 0.172
ENSG00000121350 E017 0.3806233 0.016304798 0.069770268   12 21460903 21461024 122 + 0.000 0.272 12.637
ENSG00000121350 E018 3.5122902 0.004164991 0.241210493 0.53071622 12 21461025 21461154 130 + 0.692 0.592 -0.431
ENSG00000121350 E019 4.6752862 0.054472056 0.290025958 0.58365421 12 21462008 21462120 113 + 0.654 0.851 0.799
ENSG00000121350 E020 0.5089233 0.151272780 0.043203001 0.20272409 12 21462121 21462125 5 + 0.000 0.335 12.852
ENSG00000121350 E021 2.2251099 0.098490796 0.238958010 0.52791387 12 21462740 21462862 123 + 0.388 0.623 1.146
ENSG00000121350 E022 1.7392537 0.135640219 0.122161783 0.36965180 12 21467290 21467480 191 + 0.261 0.592 1.816
ENSG00000121350 E023 3.0458850 0.005107454 0.911176693 0.97178698 12 21467481 21467618 138 + 0.590 0.623 0.147
ENSG00000121350 E024 25.0537823 0.065257971 0.068717883 0.26471183 12 21468506 21471250 2745 + 1.314 1.514 0.692

Help

Please Click HERE to learn more details about the results from DEXseq.