ENSG00000121964

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000241391 ENSG00000121964 No_inf pgKDN_inf GTDC1 protein_coding protein_coding 9.455044 4.661764 10.89559 0.5036534 1.200074 1.223029 0.3886166 0.2063083 0.9595416 0.2063083 0.9595416 2.1642139 0.05147500 0.053975 0.100450 0.046475 0.9568854 0.0394561 FALSE TRUE
ENST00000344850 ENSG00000121964 No_inf pgKDN_inf GTDC1 protein_coding protein_coding 9.455044 4.661764 10.89559 0.5036534 1.200074 1.223029 0.6772940 0.0000000 2.0318820 0.0000000 1.3082451 7.6737557 0.06410000 0.000000 0.192300 0.192300 0.6706048 0.0394561 FALSE TRUE
ENST00000409298 ENSG00000121964 No_inf pgKDN_inf GTDC1 protein_coding protein_coding 9.455044 4.661764 10.89559 0.5036534 1.200074 1.223029 1.1925564 0.3165445 0.6001491 0.3165445 0.6001491 0.9018820 0.10883333 0.082825 0.044250 -0.038575 0.9563475 0.0394561 FALSE TRUE
ENST00000429978 ENSG00000121964 No_inf pgKDN_inf GTDC1 protein_coding protein_coding_CDS_not_defined 9.455044 4.661764 10.89559 0.5036534 1.200074 1.223029 0.5684451 0.0000000 1.7053353 0.0000000 0.9867677 7.4223468 0.04420000 0.000000 0.132600 0.132600 0.5970056 0.0394561   FALSE
ENST00000484303 ENSG00000121964 No_inf pgKDN_inf GTDC1 protein_coding retained_intron 9.455044 4.661764 10.89559 0.5036534 1.200074 1.223029 1.1896532 0.7838760 0.7273381 0.3466210 0.2870640 -0.1065872 0.12790833 0.159625 0.066775 -0.092850 0.7932478 0.0394561   FALSE
ENST00000491448 ENSG00000121964 No_inf pgKDN_inf GTDC1 protein_coding retained_intron 9.455044 4.661764 10.89559 0.5036534 1.200074 1.223029 0.9301388 0.3740068 1.2376902 0.1549178 0.1656827 1.7000561 0.09350833 0.077125 0.115025 0.037900 0.8515618 0.0394561 FALSE TRUE
ENST00000618778 ENSG00000121964 No_inf pgKDN_inf GTDC1 protein_coding protein_coding 9.455044 4.661764 10.89559 0.5036534 1.200074 1.223029 0.9946940 1.3800496 0.9569395 0.8102102 0.9569395 -0.5236388 0.13725833 0.296225 0.070575 -0.225650 0.7003283 0.0394561 FALSE TRUE
MSTRG.17062.15 ENSG00000121964 No_inf pgKDN_inf GTDC1 protein_coding   9.455044 4.661764 10.89559 0.5036534 1.200074 1.223029 0.6725011 0.5098992 0.0000000 0.5098992 0.0000000 -5.7001600 0.07379167 0.095025 0.000000 -0.095025 0.7793839 0.0394561 FALSE TRUE
MSTRG.17062.4 ENSG00000121964 No_inf pgKDN_inf GTDC1 protein_coding   9.455044 4.661764 10.89559 0.5036534 1.200074 1.223029 0.6632826 0.0000000 1.7529608 0.0000000 0.5373278 7.4618566 0.06656667 0.000000 0.181925 0.181925 0.0394561 0.0394561 FALSE TRUE
MSTRG.17062.6 ENSG00000121964 No_inf pgKDN_inf GTDC1 protein_coding   9.455044 4.661764 10.89559 0.5036534 1.200074 1.223029 0.9423499 0.0000000 0.0000000 0.0000000 0.0000000 0.0000000 0.08012500 0.000000 0.000000 0.000000   0.0394561 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000121964 E001 4.1677698 0.0437214130 0.029105407 0.16006638 2 143938068 143945753 7686 - 0.564 0.874 1.283
ENSG00000121964 E002 0.0000000       2 143945754 143945882 129 -      
ENSG00000121964 E003 0.0000000       2 143945883 143946013 131 -      
ENSG00000121964 E004 0.0000000       2 143946014 143946015 2 -      
ENSG00000121964 E005 0.0000000       2 143946016 143946022 7 -      
ENSG00000121964 E006 0.1170040 0.0119395217 1.000000000   2 143946023 143946032 10 - 0.067 0.000 -11.171
ENSG00000121964 E007 0.9675598 0.2136134428 0.681435715 0.86827810 2 143946033 143946065 33 - 0.263 0.318 0.378
ENSG00000121964 E008 23.1437757 0.0006898702 0.254956938 0.54686821 2 143946066 143946826 761 - 1.332 1.406 0.258
ENSG00000121964 E009 10.4974970 0.0018460110 0.633789514 0.84345754 2 143946827 143947135 309 - 1.047 1.015 -0.117
ENSG00000121964 E010 0.0000000       2 143950945 143951012 68 -      
ENSG00000121964 E011 4.6244437 0.0036536802 0.194199675 0.47398177 2 143951982 143952073 92 - 0.668 0.830 0.654
ENSG00000121964 E012 4.4653631 0.0172371123 0.776132703 0.91405235 2 143952773 143952843 71 - 0.726 0.696 -0.128
ENSG00000121964 E013 4.3555427 0.0032741517 0.877618346 0.95843899 2 143957195 143957339 145 - 0.698 0.726 0.113
ENSG00000121964 E014 3.5278057 0.0040819083 0.293830152 0.58730886 2 143970653 143970762 110 - 0.583 0.726 0.611
ENSG00000121964 E015 6.0283936 0.0056501944 0.519922174 0.77454100 2 144005751 144007181 1431 - 0.845 0.781 -0.249
ENSG00000121964 E016 6.2668674 0.0282077743 0.862254422 0.95244086 2 144007182 144007333 152 - 0.844 0.830 -0.056
ENSG00000121964 E017 5.7185564 0.0027659809 0.001330503 0.01866635 2 144007334 144007535 202 - 0.903 0.500 -1.694
ENSG00000121964 E018 0.0000000       2 144127924 144128044 121 -      
ENSG00000121964 E019 0.0000000       2 144128246 144128322 77 -      
ENSG00000121964 E020 6.1208693 0.0027717681 0.088157300 0.30793673 2 144141882 144142055 174 - 0.884 0.695 -0.749
ENSG00000121964 E021 2.4151408 0.0073327071 0.831120688 0.93899002 2 144145572 144145619 48 - 0.522 0.500 -0.109
ENSG00000121964 E022 4.0875520 0.0038051458 0.465769162 0.73474662 2 144145620 144145739 120 - 0.713 0.627 -0.361
ENSG00000121964 E023 0.1271363 0.0135019272 0.234957267   2 144145880 144145905 26 - 0.000 0.134 12.155
ENSG00000121964 E024 0.4886223 0.0394868897 0.461987150   2 144177135 144177240 106 - 0.125 0.236 1.113
ENSG00000121964 E025 2.5779412 0.0699456439 0.096000949 0.32271972 2 144178308 144178833 526 - 0.426 0.696 1.251
ENSG00000121964 E026 0.1268540 0.0123568514 0.235598310   2 144178834 144178834 1 - 0.000 0.134 12.157
ENSG00000121964 E027 0.3631227 0.0167271597 1.000000000   2 144178835 144178960 126 - 0.125 0.134 0.113
ENSG00000121964 E028 5.8890767 0.0027566614 0.230425970 0.51898401 2 144208603 144208804 202 - 0.855 0.726 -0.511
ENSG00000121964 E029 0.0000000       2 144210835 144211237 403 -      
ENSG00000121964 E030 3.1429734 0.1101967846 0.767447478 0.90994355 2 144211515 144211579 65 - 0.602 0.589 -0.057
ENSG00000121964 E031 0.1176306 0.0119018200 1.000000000   2 144211580 144211597 18 - 0.067 0.000 -11.171
ENSG00000121964 E032 0.9515410 0.0123130047 0.205356244 0.48860765 2 144230241 144230322 82 - 0.335 0.134 -1.694
ENSG00000121964 E033 1.6877354 0.0101921550 0.768417363 0.91048371 2 144235676 144235737 62 - 0.426 0.387 -0.209
ENSG00000121964 E034 0.0000000       2 144235738 144235740 3 -      
ENSG00000121964 E035 0.0000000       2 144237244 144237341 98 -      
ENSG00000121964 E036 0.1170040 0.0119395217 1.000000000   2 144294365 144294493 129 - 0.067 0.000 -11.171
ENSG00000121964 E037 0.0000000       2 144295275 144295318 44 -      
ENSG00000121964 E038 0.2537694 0.0162567677 0.073166556   2 144317479 144317588 110 - 0.000 0.236 13.044
ENSG00000121964 E039 0.2545247 0.1544747623 0.091467725   2 144319719 144319868 150 - 0.000 0.236 12.851
ENSG00000121964 E040 0.0000000       2 144319869 144319870 2 -      
ENSG00000121964 E041 0.1272623 0.0124278654 0.235538070   2 144320563 144320612 50 - 0.000 0.134 12.157
ENSG00000121964 E042 0.6016016 0.1922678492 0.638221943 0.84580835 2 144332439 144332568 130 - 0.222 0.134 -0.888

Help

Please Click HERE to learn more details about the results from DEXseq.