ENSG00000122025

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000241453 ENSG00000122025 No_inf pgKDN_inf FLT3 protein_coding protein_coding 13.58762 34.66681 3.508429 0.9021887 0.2954843 -3.300968 2.4870715 5.643160 1.5263280 1.3275134 0.5865903 -1.879571 0.24943333 0.162950 0.48335 0.320400 6.740744e-01 1.758684e-06 FALSE TRUE
ENST00000380987 ENSG00000122025 No_inf pgKDN_inf FLT3 protein_coding nonsense_mediated_decay 13.58762 34.66681 3.508429 0.9021887 0.2954843 -3.300968 0.6097801 1.162729 0.2326418 0.4425687 0.2326418 -2.272970 0.08676667 0.032875 0.05525 0.022375 1.000000e+00 1.758684e-06 TRUE TRUE
MSTRG.7616.2 ENSG00000122025 No_inf pgKDN_inf FLT3 protein_coding   13.58762 34.66681 3.508429 0.9021887 0.2954843 -3.300968 4.6465899 13.939770 0.0000000 1.5827949 0.0000000 -10.446026 0.13390000 0.401700 0.00000 -0.401700 1.758684e-06 1.758684e-06 FALSE TRUE
MSTRG.7616.4 ENSG00000122025 No_inf pgKDN_inf FLT3 protein_coding   13.58762 34.66681 3.508429 0.9021887 0.2954843 -3.300968 5.6860472 13.446752 1.7494589 0.7063636 0.6736703 -2.935126 0.52551667 0.389325 0.46140 0.072075 9.060792e-01 1.758684e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000122025 E001 1.1347871 0.0209334536 0.9411532059 0.98341173 13 28003274 28003434 161 - 0.243 0.215 -0.223
ENSG00000122025 E002 3.0193682 0.0047711004 0.6547572336 0.85513552 13 28003435 28003613 179 - 0.511 0.429 -0.415
ENSG00000122025 E003 3.4186216 0.0044725946 0.2424117747 0.53208879 13 28003614 28003648 35 - 0.243 0.489 1.478
ENSG00000122025 E004 38.5917967 0.0009126172 0.0006599911 0.01083261 13 28003649 28003946 298 - 1.060 1.386 1.155
ENSG00000122025 E005 45.9201716 0.0003309307 0.6719807033 0.86407132 13 28003947 28004174 228 - 1.410 1.440 0.104
ENSG00000122025 E006 0.2539903 0.0160200750 1.0000000000   13 28009306 28009490 185 - 0.000 0.065 8.887
ENSG00000122025 E007 34.1013325 0.0036266785 0.1924100811 0.47230317 13 28014452 28014557 106 - 1.203 1.323 0.421
ENSG00000122025 E008 30.5775033 0.0004683998 0.0802602147 0.29081320 13 28015157 28015256 100 - 1.113 1.281 0.598
ENSG00000122025 E009 25.7350657 0.0088373881 0.8808702359 0.95997974 13 28015590 28015701 112 - 1.182 1.199 0.061
ENSG00000122025 E010 20.8974277 0.0016148507 0.3132625010 0.60640741 13 28018467 28018589 123 - 1.203 1.104 -0.355
ENSG00000122025 E011 23.5264225 0.0006159954 0.0285129546 0.15809784 13 28023350 28023477 128 - 0.928 1.179 0.915
ENSG00000122025 E012 21.0820626 0.0006585941 0.3830395486 0.66916521 13 28024861 28024943 83 - 1.030 1.125 0.344
ENSG00000122025 E013 0.3812526 0.0164293166 1.0000000000   13 28025284 28025415 132 - 0.000 0.094 9.429
ENSG00000122025 E014 31.7498142 0.0004235285 0.5763733281 0.81048908 13 28027088 28027241 154 - 1.326 1.279 -0.164
ENSG00000122025 E015 20.1250313 0.0007195536 0.1534588630 0.41809711 13 28028178 28028288 111 - 1.223 1.084 -0.496
ENSG00000122025 E016 16.6271686 0.0074270977 0.7224820990 0.88843745 13 28033887 28033991 105 - 1.060 1.019 -0.147
ENSG00000122025 E017 16.4992746 0.0082248723 0.7037642229 0.87949423 13 28034082 28034214 133 - 1.060 1.016 -0.160
ENSG00000122025 E018 17.9309055 0.0008162479 0.2594706073 0.55197445 13 28034301 28034407 107 - 0.928 1.064 0.500
ENSG00000122025 E019 21.6640508 0.0172807858 0.5775721646 0.81126884 13 28035495 28035673 179 - 1.182 1.122 -0.213
ENSG00000122025 E020 16.9644965 0.0038151241 0.1086544659 0.34594977 13 28035935 28036043 109 - 1.182 1.013 -0.613
ENSG00000122025 E021 12.1861809 0.0115040704 0.1589097007 0.42601828 13 28037185 28037288 104 - 1.060 0.884 -0.655
ENSG00000122025 E022 15.4650968 0.0009911812 0.2283794478 0.51697377 13 28048275 28048443 169 - 1.113 0.981 -0.481
ENSG00000122025 E023 15.2488975 0.0009347914 0.9313574266 0.97999201 13 28049384 28049537 154 - 0.999 0.988 -0.039
ENSG00000122025 E024 0.1268540 0.0123749896 0.4271337982   13 28049538 28049577 40 - 0.000 0.033 7.937
ENSG00000122025 E025 12.9661906 0.0013419249 0.5104560753 0.76800524 13 28049635 28049774 140 - 0.999 0.919 -0.300
ENSG00000122025 E026 9.1792835 0.0021499010 0.2707229834 0.56438380 13 28050095 28050222 128 - 0.928 0.782 -0.567
ENSG00000122025 E027 8.1972800 0.0017928921 0.8994506224 0.96724030 13 28052545 28052674 130 - 0.739 0.758 0.075
ENSG00000122025 E028 8.1949493 0.0469937299 0.9559180708 0.98935897 13 28057347 28057462 116 - 0.739 0.758 0.075
ENSG00000122025 E029 11.6001938 0.0234974192 0.9532689496 0.98854798 13 28061867 28062069 203 - 0.888 0.884 -0.018
ENSG00000122025 E030 6.3677966 0.0025803983 0.0038534690 0.04137931 13 28070491 28070612 122 - 0.999 0.615 -1.522
ENSG00000122025 E031 0.2537694 0.0164510964 1.0000000000   13 28071674 28071725 52 - 0.000 0.065 8.887
ENSG00000122025 E032 3.2277848 0.0046773151 0.0028786058 0.03348759 13 28100468 28100592 125 - 0.844 0.388 -2.053

Help

Please Click HERE to learn more details about the results from DEXseq.