ENSG00000122026

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000311549 ENSG00000122026 No_inf pgKDN_inf RPL21 protein_coding protein_coding 1616.17 1331.94 1889.62 11.86134 8.558891 0.5045638 639.6304 590.3379 726.0607 4.601903 23.15839 0.2985446 0.3992333 0.443275 0.384150 -0.059125 0.03240272 0.016441 FALSE  
ENST00000493317 ENSG00000122026 No_inf pgKDN_inf RPL21 protein_coding protein_coding 1616.17 1331.94 1889.62 11.86134 8.558891 0.5045638 882.8975 691.1609 1028.2937 13.249432 22.59211 0.5731520 0.5447500 0.518775 0.544325 0.025550 0.65865664 0.016441 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000122026 E001 2.7715062 6.438089e-02 0.240261464 0.52946413 13 27251362 27251557 196 + 0.654 0.464 -0.875
ENSG00000122026 E002 0.8312037 1.263386e-01 0.130449655 0.38318565 13 27251558 27251560 3 + 0.364 0.105 -2.266
ENSG00000122026 E003 0.9672138 4.399902e-02 0.702176084 0.87884059 13 27251561 27251578 18 + 0.321 0.260 -0.420
ENSG00000122026 E004 0.9672138 4.399902e-02 0.702176084 0.87884059 13 27251579 27251582 4 + 0.321 0.260 -0.420
ENSG00000122026 E005 0.9672138 4.399902e-02 0.702176084 0.87884059 13 27251583 27251585 3 + 0.321 0.260 -0.420
ENSG00000122026 E006 0.7432459 2.881598e-02 0.285087273 0.57878352 13 27251586 27251596 11 + 0.158 0.321 1.317
ENSG00000122026 E007 2.3059515 1.886044e-01 0.587042671 0.81688005 13 27251597 27251656 60 + 0.560 0.464 -0.461
ENSG00000122026 E008 1.4623198 1.824836e-02 0.846151835 0.94538473 13 27251657 27251699 43 + 0.404 0.374 -0.168
ENSG00000122026 E009 1.9863175 6.923021e-03 0.053637353 0.23056993 13 27251700 27251850 151 + 0.321 0.603 1.455
ENSG00000122026 E010 0.6263978 1.414141e-02 0.109329674 0.34702134 13 27253705 27253764 60 + 0.086 0.321 2.315
ENSG00000122026 E011 289.2146883 8.198057e-05 0.028418619 0.15780189 13 27253765 27253843 79 + 2.479 2.441 -0.125
ENSG00000122026 E012 286.5270211 8.005671e-05 0.027077093 0.15296700 13 27254220 27254281 62 + 2.475 2.437 -0.127
ENSG00000122026 E013 3.5246245 4.383191e-03 0.478459453 0.74448191 13 27254282 27254467 186 + 0.694 0.603 -0.393
ENSG00000122026 E014 3.5388841 3.960775e-03 0.973989503 0.99538773 13 27254944 27255063 120 + 0.654 0.658 0.018
ENSG00000122026 E015 4.9689800 2.771913e-02 0.361611009 0.65105916 13 27255064 27255241 178 + 0.826 0.707 -0.476
ENSG00000122026 E016 398.2684506 5.588492e-05 0.988041705 0.99989008 13 27255242 27255349 108 + 2.600 2.600 0.000
ENSG00000122026 E017 347.8968550 6.139183e-05 0.958625687 0.99019693 13 27255350 27255354 5 + 2.541 2.542 0.002
ENSG00000122026 E018 1.0891878 1.101936e-02 0.498988215 0.75927365 13 27255355 27255400 46 + 0.365 0.260 -0.683
ENSG00000122026 E019 6.8289406 2.124306e-03 0.985220976 0.99899506 13 27255401 27255856 456 + 0.892 0.894 0.007
ENSG00000122026 E020 595.3205346 4.765896e-05 0.100009152 0.33048794 13 27256184 27256334 151 + 2.766 2.784 0.059
ENSG00000122026 E021 237.3848563 9.154270e-05 0.006563645 0.06025593 13 27256436 27256691 256 + 2.352 2.403 0.171

Help

Please Click HERE to learn more details about the results from DEXseq.