ENSG00000122085

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000391980 ENSG00000122085 No_inf pgKDN_inf MTERF4 protein_coding protein_coding 17.54722 19.8521 15.7056 0.3322696 0.6738212 -0.3378208 7.7074175 9.406442 6.1560385 0.3773257 0.8531262 -0.6108382 0.44048333 0.4734 0.397325 -0.076075 0.83046673 0.02106086 FALSE TRUE
ENST00000455202 ENSG00000122085 No_inf pgKDN_inf MTERF4 protein_coding protein_coding_CDS_not_defined 17.54722 19.8521 15.7056 0.3322696 0.6738212 -0.3378208 3.2550087 4.037900 2.4681274 0.6939716 0.9545105 -0.7079234 0.18608333 0.2036 0.161250 -0.042350 0.84082335 0.02106086   FALSE
ENST00000460915 ENSG00000122085 No_inf pgKDN_inf MTERF4 protein_coding retained_intron 17.54722 19.8521 15.7056 0.3322696 0.6738212 -0.3378208 1.3523078 1.954127 0.9752197 0.1204526 0.1371937 -0.9953710 0.07481667 0.0984 0.061800 -0.036600 0.80569474 0.02106086   FALSE
ENST00000476564 ENSG00000122085 No_inf pgKDN_inf MTERF4 protein_coding retained_intron 17.54722 19.8521 15.7056 0.3322696 0.6738212 -0.3378208 0.7676738 0.000000 1.9674340 0.0000000 0.6581730 7.6274857 0.04824167 0.0000 0.121200 0.121200 0.02106086 0.02106086   FALSE
MSTRG.17847.3 ENSG00000122085 No_inf pgKDN_inf MTERF4 protein_coding   17.54722 19.8521 15.7056 0.3322696 0.6738212 -0.3378208 0.9195053 2.037573 0.2274465 0.2860227 0.2274465 -3.1082403 0.04858333 0.1026 0.014250 -0.088350 0.10565617 0.02106086 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000122085 E001 0.0000000       2 241072169 241075053 2885 -      
ENSG00000122085 E002 1.6174945 0.0608952105 0.52525628 0.77809005 2 241075054 241075682 629 - 0.342 0.448 0.594
ENSG00000122085 E003 0.0000000       2 241087094 241087098 5 -      
ENSG00000122085 E004 0.2340080 0.2026887850 0.16689983   2 241087099 241087161 63 - 0.203 0.000 -13.449
ENSG00000122085 E005 0.4877159 0.4319093160 0.75325292   2 241087162 241087203 42 - 0.203 0.146 -0.573
ENSG00000122085 E006 0.2537079 0.2379173295 0.46937833   2 241087204 241087224 21 - 0.000 0.146 11.848
ENSG00000122085 E007 40.1370221 0.0004509807 0.41278542 0.69378421 2 241087225 241088904 1680 - 1.580 1.616 0.121
ENSG00000122085 E008 3.6157988 0.0101221596 0.07587192 0.28147450 2 241088905 241089040 136 - 0.490 0.733 1.077
ENSG00000122085 E009 3.3503905 0.1022913732 0.43954040 0.71551864 2 241089041 241089168 128 - 0.530 0.682 0.672
ENSG00000122085 E010 1.0878334 0.0114539572 0.11216195 0.35199248 2 241089169 241089187 19 - 0.446 0.205 -1.575
ENSG00000122085 E011 3.6968989 0.2047097023 0.86667510 0.95408027 2 241089188 241089224 37 - 0.689 0.644 -0.191
ENSG00000122085 E012 4.1506850 0.0522171106 0.12151737 0.36902689 2 241089225 241089266 42 - 0.825 0.603 -0.917
ENSG00000122085 E013 2.4243374 0.1177098716 0.06597300 0.25868321 2 241089267 241089272 6 - 0.689 0.381 -1.469
ENSG00000122085 E014 6.0940646 0.0031857215 0.01107435 0.08594017 2 241089273 241089365 93 - 0.985 0.717 -1.041
ENSG00000122085 E015 2.9154988 0.0128285960 0.03156279 0.16774806 2 241089980 241090005 26 - 0.739 0.448 -1.312
ENSG00000122085 E016 1.9544922 0.0229435465 0.20975670 0.49420836 2 241090006 241090044 39 - 0.567 0.381 -0.938
ENSG00000122085 E017 0.2362687 0.0158855338 0.13280654   2 241090278 241090302 25 - 0.203 0.000 -13.825
ENSG00000122085 E018 0.7266538 0.0180663037 0.19473921 0.47471479 2 241090303 241090449 147 - 0.341 0.146 -1.575
ENSG00000122085 E019 0.0000000       2 241091895 241092114 220 -      
ENSG00000122085 E020 0.0000000       2 241094277 241094405 129 -      
ENSG00000122085 E021 0.0000000       2 241094406 241094429 24 -      
ENSG00000122085 E022 0.0000000       2 241094430 241094432 3 -      
ENSG00000122085 E023 0.0000000       2 241094433 241094596 164 -      
ENSG00000122085 E024 0.0000000       2 241094597 241095129 533 -      
ENSG00000122085 E025 0.0000000       2 241095130 241095570 441 -      
ENSG00000122085 E026 15.5104308 0.0049877986 0.06372906 0.25417165 2 241095571 241095868 298 - 1.112 1.256 0.512
ENSG00000122085 E027 27.7115277 0.0007325917 0.24545978 0.53595513 2 241095869 241096139 271 - 1.407 1.469 0.217
ENSG00000122085 E028 17.0614127 0.0342052749 0.59627884 0.82249879 2 241096140 241096392 253 - 1.211 1.266 0.195
ENSG00000122085 E029 6.3827148 0.0193142944 0.41139335 0.69311907 2 241096393 241096438 46 - 0.912 0.821 -0.353
ENSG00000122085 E030 0.9971702 0.3156141458 0.64674575 0.85045457 2 241096601 241096713 113 - 0.203 0.343 1.011
ENSG00000122085 E031 2.1128855 0.0063943750 0.36079312 0.65037939 2 241096926 241097186 261 - 0.397 0.532 0.688
ENSG00000122085 E032 0.6174916 0.0202844420 0.99434903 1.00000000 2 241097187 241097242 56 - 0.203 0.205 0.009
ENSG00000122085 E033 13.3230012 0.0070634430 0.91533814 0.97349447 2 241097243 241097427 185 - 1.151 1.141 -0.035
ENSG00000122085 E034 0.3806233 0.0164907131 0.20600405   2 241098806 241098887 82 - 0.000 0.205 12.687
ENSG00000122085 E035 0.8525992 0.0123028355 0.36921932 0.65747078 2 241099168 241099395 228 - 0.341 0.205 -0.991
ENSG00000122085 E036 3.1024706 0.0583447235 0.48997932 0.75275425 2 241099396 241099398 3 - 0.530 0.644 0.512
ENSG00000122085 E037 19.0778412 0.0007889708 0.52053255 0.77482714 2 241099399 241099894 496 - 1.316 1.275 -0.144
ENSG00000122085 E038 0.2541163 0.0161263492 0.41254055   2 241101164 241101221 58 - 0.000 0.146 12.168
ENSG00000122085 E039 0.0000000       2 241102140 241102252 113 -      
ENSG00000122085 E040 3.6812837 0.0040120395 0.47044871 0.73812109 2 241102253 241102332 80 - 0.715 0.624 -0.383

Help

Please Click HERE to learn more details about the results from DEXseq.