ENSG00000122126

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000357121 ENSG00000122126 No_inf pgKDN_inf OCRL protein_coding protein_coding 4.385043 5.164057 3.568731 0.2390037 0.1342587 -0.5318475 0.7387167 0.7139750 0.8514321 0.30751703 0.50107653 0.2507971 0.17401667 0.132000 0.237000 0.105000 0.98316705 0.00166918 FALSE TRUE
ENST00000371113 ENSG00000122126 No_inf pgKDN_inf OCRL protein_coding protein_coding 4.385043 5.164057 3.568731 0.2390037 0.1342587 -0.5318475 0.2629067 0.0000000 0.3386764 0.00000000 0.33867640 5.1238168 0.06634167 0.000000 0.104700 0.104700 0.82595872 0.00166918 FALSE TRUE
ENST00000463271 ENSG00000122126 No_inf pgKDN_inf OCRL protein_coding protein_coding_CDS_not_defined 4.385043 5.164057 3.568731 0.2390037 0.1342587 -0.5318475 1.0171033 1.6224872 0.0000000 0.19064582 0.00000000 -7.3509279 0.20947500 0.313925 0.000000 -0.313925 0.00166918 0.00166918   FALSE
ENST00000647245 ENSG00000122126 No_inf pgKDN_inf OCRL protein_coding nonsense_mediated_decay 4.385043 5.164057 3.568731 0.2390037 0.1342587 -0.5318475 0.1040283 0.0000000 0.3120850 0.00000000 0.31208498 5.0093695 0.02999167 0.000000 0.089975 0.089975 0.82022980 0.00166918 TRUE TRUE
ENST00000689093 ENSG00000122126 No_inf pgKDN_inf OCRL protein_coding nonsense_mediated_decay 4.385043 5.164057 3.568731 0.2390037 0.1342587 -0.5318475 0.4061181 0.5071683 0.2296906 0.08701786 0.03618863 -1.1094605 0.09018333 0.098700 0.064075 -0.034625 0.88459979 0.00166918 FALSE FALSE
MSTRG.30419.8 ENSG00000122126 No_inf pgKDN_inf OCRL protein_coding   4.385043 5.164057 3.568731 0.2390037 0.1342587 -0.5318475 1.6249289 2.2113018 1.6196026 0.21176489 0.61706579 -0.4468853 0.37601667 0.435200 0.444650 0.009450 1.00000000 0.00166918 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000122126 E001 0.0000000       X 129539849 129539939 91 +      
ENSG00000122126 E002 0.0000000       X 129540259 129540274 16 +      
ENSG00000122126 E003 0.0000000       X 129540275 129540299 25 +      
ENSG00000122126 E004 0.3731628 0.1157967366 0.764979469   X 129540300 129540478 179 + 0.106 0.157 0.653
ENSG00000122126 E005 0.0000000       X 129540744 129540747 4 +      
ENSG00000122126 E006 0.8631426 0.0136054026 0.956981874 0.98975055 X 129540748 129540823 76 + 0.262 0.271 0.068
ENSG00000122126 E007 0.0000000       X 129543469 129543978 510 +      
ENSG00000122126 E008 0.8631426 0.0136054026 0.956981874 0.98975055 X 129544958 129544972 15 + 0.262 0.271 0.068
ENSG00000122126 E009 0.8631426 0.0136054026 0.956981874 0.98975055 X 129544973 129545037 65 + 0.262 0.271 0.068
ENSG00000122126 E010 0.2455571 0.0163309850 0.849755193   X 129548563 129548599 37 + 0.106 0.085 -0.347
ENSG00000122126 E011 0.3726934 0.0165811700 0.744673605   X 129548600 129548601 2 + 0.106 0.157 0.653
ENSG00000122126 E012 0.1272623 0.0123932177 0.682885185   X 129549648 129549917 270 + 0.000 0.085 10.129
ENSG00000122126 E013 0.0000000       X 129553236 129553273 38 +      
ENSG00000122126 E014 2.7402911 0.0055031480 0.107308808 0.34329398 X 129553274 129554393 1120 + 0.424 0.651 1.068
ENSG00000122126 E015 0.6337937 0.2216406187 0.070406314 0.26854980 X 129554394 129554446 53 + 0.000 0.319 11.943
ENSG00000122126 E016 0.1265070 0.0125485785 0.682549125   X 129555675 129555743 69 + 0.000 0.085 10.129
ENSG00000122126 E017 1.5770226 0.0091783587 0.205620698 0.48898184 X 129557325 129557435 111 + 0.506 0.319 -1.025
ENSG00000122126 E018 1.0708058 0.0107139293 0.004954764 0.04929008 X 129557861 129557950 90 + 0.506 0.085 -3.347
ENSG00000122126 E019 2.1970333 0.0065204742 0.324780122 0.61717607 X 129558633 129558753 121 + 0.575 0.437 -0.669
ENSG00000122126 E020 3.4201168 0.0230217595 0.340027309 0.63172693 X 129558840 129559001 162 + 0.711 0.582 -0.554
ENSG00000122126 E021 2.6796416 0.0202631819 0.174588336 0.44840605 X 129560550 129560651 102 + 0.662 0.470 -0.878
ENSG00000122126 E022 2.0887135 0.0076593971 0.795463444 0.92234271 X 129561179 129561243 65 + 0.506 0.470 -0.177
ENSG00000122126 E023 2.0861979 0.0077420727 0.794327141 0.92153499 X 129561244 129561293 50 + 0.506 0.470 -0.177
ENSG00000122126 E024 2.2242829 0.0113046344 0.676009506 0.86582531 X 129562384 129562500 117 + 0.467 0.530 0.305
ENSG00000122126 E025 2.5870973 0.0057488065 0.920584567 0.97521456 X 129562599 129562786 188 + 0.542 0.557 0.068
ENSG00000122126 E026 2.2043370 0.0066893148 0.607100421 0.82902637 X 129565772 129565883 112 + 0.542 0.470 -0.347
ENSG00000122126 E027 2.1927586 0.0558671767 0.376901120 0.66406289 X 129567254 129567363 110 + 0.575 0.437 -0.669
ENSG00000122126 E028 2.8369383 0.0056693041 0.643136450 0.84869546 X 129569264 129569399 136 + 0.542 0.606 0.290
ENSG00000122126 E029 3.8064078 0.0174377760 0.887566841 0.96240074 X 129575140 129575250 111 + 0.687 0.671 -0.067
ENSG00000122126 E030 0.0000000       X 129575654 129575719 66 +      
ENSG00000122126 E031 5.1622635 0.0143165538 0.855287914 0.94910977 X 129575897 129576062 166 + 0.796 0.778 -0.071
ENSG00000122126 E032 5.2484573 0.0029680225 0.204669792 0.48769367 X 129576317 129576552 236 + 0.866 0.728 -0.549
ENSG00000122126 E033 0.1170040 0.0118307915 0.420582034   X 129576553 129576765 213 + 0.106 0.000 -11.458
ENSG00000122126 E034 0.4893505 0.0163599431 0.808593815   X 129584344 129584367 24 + 0.191 0.157 -0.347
ENSG00000122126 E035 2.8413774 0.0135918955 0.650658600 0.85292969 X 129587002 129587118 117 + 0.542 0.606 0.290
ENSG00000122126 E036 1.7047277 0.0087480598 0.325785069 0.61827974 X 129588179 129588263 85 + 0.506 0.362 -0.762
ENSG00000122126 E037 3.0401897 0.0071626868 0.110270009 0.34842287 X 129588886 129589013 128 + 0.711 0.501 -0.932
ENSG00000122126 E038 0.0000000       X 129589237 129589364 128 +      
ENSG00000122126 E039 0.0000000       X 129589589 129589844 256 +      
ENSG00000122126 E040 3.1780302 0.0091944417 0.318613919 0.61126173 X 129589845 129589956 112 + 0.687 0.557 -0.570
ENSG00000122126 E041 54.5810983 0.0003704826 0.003648799 0.03986869 X 129590146 129592561 2416 + 1.686 1.775 0.303

Help

Please Click HERE to learn more details about the results from DEXseq.