ENSG00000122335

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000607000 ENSG00000122335 No_inf pgKDN_inf SERAC1 protein_coding retained_intron 2.795287 2.810649 2.979338 0.3002597 0.1874685 0.08379893 0.37665935 0.4284937 0.3900040 0.1648866 0.1225682 -0.1325417 0.14004167 0.160125 0.140125 -0.020000 1.00000000 0.04405302 FALSE FALSE
ENST00000643093 ENSG00000122335 No_inf pgKDN_inf SERAC1 protein_coding protein_coding_CDS_not_defined 2.795287 2.810649 2.979338 0.3002597 0.1874685 0.08379893 0.07260071 0.2178021 0.0000000 0.2178021 0.0000000 -4.5097093 0.01970833 0.059125 0.000000 -0.059125 0.83637610 0.04405302   FALSE
ENST00000645172 ENSG00000122335 No_inf pgKDN_inf SERAC1 protein_coding nonsense_mediated_decay 2.795287 2.810649 2.979338 0.3002597 0.1874685 0.08379893 0.50130648 0.1581612 0.9318863 0.1581612 0.5448447 2.4857082 0.18012500 0.060375 0.327575 0.267200 0.78181413 0.04405302 FALSE TRUE
ENST00000646208 ENSG00000122335 No_inf pgKDN_inf SERAC1 protein_coding protein_coding 2.795287 2.810649 2.979338 0.3002597 0.1874685 0.08379893 0.62797235 1.2568918 0.0000000 0.4244216 0.0000000 -6.9851495 0.22051667 0.428075 0.000000 -0.428075 0.04405302 0.04405302 FALSE TRUE
ENST00000647468 ENSG00000122335 No_inf pgKDN_inf SERAC1 protein_coding protein_coding 2.795287 2.810649 2.979338 0.3002597 0.1874685 0.08379893 0.78483164 0.3878040 1.5298546 0.3878040 0.6745812 1.9526645 0.27880833 0.167750 0.490425 0.322675 0.47150166 0.04405302 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000122335 E001 0.2455571 0.016590956 0.947602000   6 158109519 158109534 16 - 0.089 0.101 0.204
ENSG00000122335 E002 0.2455571 0.016590956 0.947602000   6 158109535 158109540 6 - 0.089 0.101 0.204
ENSG00000122335 E003 1.8695005 0.007932791 0.044336587 0.20585270 6 158109541 158109690 150 - 0.282 0.590 1.664
ENSG00000122335 E004 0.6353689 0.016067295 0.015927923 0.10944791 6 158109691 158109692 2 - 0.000 0.364 14.167
ENSG00000122335 E005 8.4966959 0.001812625 0.126455724 0.37690442 6 158109693 158110224 532 - 0.894 1.051 0.583
ENSG00000122335 E006 4.4981617 0.003403164 0.361927159 0.65130052 6 158110225 158110598 374 - 0.779 0.694 -0.348
ENSG00000122335 E007 0.9708940 0.012538398 0.555148001 0.79778462 6 158110599 158110619 21 - 0.330 0.252 -0.533
ENSG00000122335 E008 0.8457392 0.015491717 0.302044655 0.59523810 6 158110620 158110626 7 - 0.330 0.183 -1.118
ENSG00000122335 E009 1.3258284 0.010806172 0.166397233 0.43660756 6 158110627 158110667 41 - 0.451 0.252 -1.211
ENSG00000122335 E010 4.0544762 0.003714343 0.432133721 0.70960791 6 158110668 158110871 204 - 0.645 0.758 0.467
ENSG00000122335 E011 10.2674492 0.002808716 0.783980323 0.91683423 6 158110872 158111502 631 - 1.052 1.051 -0.002
ENSG00000122335 E012 1.2422850 0.010363877 0.157257557 0.42384334 6 158111503 158113448 1946 - 0.226 0.453 1.427
ENSG00000122335 E013 3.3056047 0.017005182 0.967389799 0.99341205 6 158113449 158113592 144 - 0.622 0.645 0.097
ENSG00000122335 E014 0.1268540 0.012498225 0.498227266   6 158114471 158114534 64 - 0.000 0.101 12.331
ENSG00000122335 E015 0.1268540 0.012498225 0.498227266   6 158114535 158114592 58 - 0.000 0.101 12.331
ENSG00000122335 E016 0.1268540 0.012498225 0.498227266   6 158114593 158114730 138 - 0.000 0.101 12.331
ENSG00000122335 E017 0.0000000       6 158114731 158114788 58 -      
ENSG00000122335 E018 1.1255024 0.059997704 0.079165370 0.28851308 6 158114789 158114825 37 - 0.163 0.453 2.012
ENSG00000122335 E019 2.3264340 0.006808080 0.971500622 0.99453344 6 158114826 158114971 146 - 0.516 0.527 0.052
ENSG00000122335 E020 1.8511243 0.254653826 0.518853948 0.77366198 6 158116185 158116282 98 - 0.374 0.527 0.789
ENSG00000122335 E021 0.7528434 0.016285607 0.074927070 0.27927551 6 158116283 158117531 1249 - 0.089 0.364 2.526
ENSG00000122335 E022 0.1186381 0.011922762 0.581324611   6 158117532 158117575 44 - 0.089 0.000 -12.760
ENSG00000122335 E023 0.3724075 0.017004988 0.533029055   6 158117576 158117726 151 - 0.089 0.183 1.204
ENSG00000122335 E024 1.3348971 0.040853121 0.460647584 0.73197902 6 158117727 158117821 95 - 0.414 0.312 -0.603
ENSG00000122335 E025 0.9637768 0.014387424 0.189062116 0.46768225 6 158119029 158119120 92 - 0.374 0.183 -1.380
ENSG00000122335 E026 1.2084801 0.010901451 0.255704431 0.54774355 6 158119121 158119170 50 - 0.414 0.252 -1.018
ENSG00000122335 E027 3.4867920 0.004039640 0.007895393 0.06850549 6 158120425 158120575 151 - 0.779 0.453 -1.448
ENSG00000122335 E028 2.9026270 0.006262187 0.149104696 0.41136696 6 158128108 158128270 163 - 0.667 0.492 -0.796
ENSG00000122335 E029 1.5780898 0.009139397 0.497288787 0.75796558 6 158130373 158130486 114 - 0.451 0.364 -0.474
ENSG00000122335 E030 0.6072604 0.016121308 0.727248459 0.89108349 6 158143056 158143184 129 - 0.226 0.183 -0.380
ENSG00000122335 E031 0.9802674 0.014583756 0.900438053 0.96768211 6 158144299 158144420 122 - 0.282 0.312 0.204
ENSG00000122335 E032 0.0000000       6 158145264 158145363 100 -      
ENSG00000122335 E033 0.6185939 0.015114169 0.585588282 0.81605908 6 158145920 158146781 862 - 0.163 0.252 0.789
ENSG00000122335 E034 0.7450359 0.014034069 0.352682337 0.64275087 6 158146782 158146869 88 - 0.163 0.312 1.204
ENSG00000122335 E035 0.3635311 0.016798111 0.638898578   6 158146870 158146913 44 - 0.163 0.101 -0.795
ENSG00000122335 E036 1.2044525 0.017102728 0.255446988 0.54743425 6 158148865 158148954 90 - 0.414 0.252 -1.018
ENSG00000122335 E037 1.3204517 0.151630282 0.236331523 0.52543134 6 158150453 158150563 111 - 0.451 0.252 -1.209
ENSG00000122335 E038 0.4805351 0.016011267 0.362245393   6 158150564 158150587 24 - 0.226 0.101 -1.380
ENSG00000122335 E039 0.4719759 0.015538762 0.054521239   6 158150588 158150589 2 - 0.282 0.000 -14.231
ENSG00000122335 E040 0.3806233 0.016110090 0.088481068   6 158151039 158151129 91 - 0.000 0.252 13.614
ENSG00000122335 E041 0.2435110 0.017540592 0.949038934   6 158152756 158152842 87 - 0.089 0.101 0.205
ENSG00000122335 E042 0.4804091 0.016043909 0.362397108   6 158155315 158155351 37 - 0.226 0.101 -1.380
ENSG00000122335 E043 0.9707670 0.032614218 0.563499691 0.80278389 6 158158273 158158364 92 - 0.330 0.252 -0.532
ENSG00000122335 E044 0.6348960 0.014504837 0.015792211 0.10879984 6 158158365 158159298 934 - 0.000 0.364 14.168
ENSG00000122335 E045 0.3798680 0.019195134 0.089257668   6 158160932 158162147 1216 - 0.000 0.252 13.613
ENSG00000122335 E046 0.0000000       6 158162148 158162152 5 -      
ENSG00000122335 E047 0.1187032 0.012093520 0.580952825   6 158166114 158166159 46 - 0.089 0.000 -12.760
ENSG00000122335 E048 0.8698452 0.014461594 0.209066219 0.49327518 6 158168140 158168280 141 - 0.163 0.364 1.526

Help

Please Click HERE to learn more details about the results from DEXseq.