ENSG00000122432

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000460286 ENSG00000122432 No_inf pgKDN_inf SPATA1 protein_coding nonsense_mediated_decay 2.008451 3.396456 1.512564 0.4894286 0.294673 -1.161769 0.08904223 0.2671267 0.0000000 0.2671267 0.00000000 -4.7924738 0.03646667 0.109400 0.000000 -0.109400 1.000000e+00 9.93425e-06 TRUE FALSE
ENST00000468437 ENSG00000122432 No_inf pgKDN_inf SPATA1 protein_coding protein_coding_CDS_not_defined 2.008451 3.396456 1.512564 0.4894286 0.294673 -1.161769 0.87207601 2.0229123 0.0000000 0.3322466 0.00000000 -7.6674042 0.39418333 0.595150 0.000000 -0.595150 6.935365e-04 9.93425e-06   FALSE
ENST00000473108 ENSG00000122432 No_inf pgKDN_inf SPATA1 protein_coding protein_coding_CDS_not_defined 2.008451 3.396456 1.512564 0.4894286 0.294673 -1.161769 0.19931203 0.3813661 0.0000000 0.3813661 0.00000000 -5.2904468 0.07050000 0.086475 0.000000 -0.086475 9.679292e-01 9.93425e-06 FALSE FALSE
ENST00000484939 ENSG00000122432 No_inf pgKDN_inf SPATA1 protein_coding protein_coding_CDS_not_defined 2.008451 3.396456 1.512564 0.4894286 0.294673 -1.161769 0.35603699 0.0000000 1.0681110 0.0000000 0.27123812 6.7523619 0.22711667 0.000000 0.681350 0.681350 9.934250e-06 9.93425e-06   FALSE
ENST00000697277 ENSG00000122432 No_inf pgKDN_inf SPATA1 protein_coding nonsense_mediated_decay 2.008451 3.396456 1.512564 0.4894286 0.294673 -1.161769 0.25090439 0.4462669 0.0000000 0.2856039 0.00000000 -5.5118060 0.13875833 0.128725 0.000000 -0.128725 7.587268e-01 9.93425e-06 TRUE FALSE
ENST00000699524 ENSG00000122432 No_inf pgKDN_inf SPATA1 protein_coding protein_coding 2.008451 3.396456 1.512564 0.4894286 0.294673 -1.161769 0.19882146 0.2231299 0.3733344 0.1249367 0.07743074 0.7174693 0.11147500 0.057450 0.276975 0.219525 4.495217e-01 9.93425e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000122432 E001 0.0000000       1 84506300 84506316 17 +      
ENSG00000122432 E002 0.0000000       1 84506317 84506381 65 +      
ENSG00000122432 E003 0.0000000       1 84506382 84506385 4 +      
ENSG00000122432 E004 0.0000000       1 84506386 84506396 11 +      
ENSG00000122432 E005 0.0000000       1 84506397 84506418 22 +      
ENSG00000122432 E006 1.1423087 0.011789782 0.016437635 0.11151539 1 84506656 84506876 221 + 0.000 0.415 11.991
ENSG00000122432 E007 2.7400390 0.006621514 0.585933782 0.81624529 1 84506877 84507320 444 + 0.481 0.584 0.488
ENSG00000122432 E008 0.7188202 0.015597089 0.008250156 0.07056199 1 84516223 84516395 173 + 0.429 0.071 -3.249
ENSG00000122432 E009 0.0000000       1 84520115 84520253 139 +      
ENSG00000122432 E010 0.6001197 0.017857661 0.025638985 0.14784700 1 84520585 84520691 107 + 0.371 0.071 -2.927
ENSG00000122432 E011 0.2435110 0.017863055 0.548806681   1 84522390 84522417 28 + 0.126 0.071 -0.927
ENSG00000122432 E012 0.4972804 0.018965407 0.812780492   1 84522418 84522507 90 + 0.126 0.185 0.658
ENSG00000122432 E013 0.3724075 0.018230765 1.000000000   1 84525696 84525749 54 + 0.126 0.132 0.073
ENSG00000122432 E014 0.3795211 0.025438057 0.351925122   1 84525845 84526073 229 + 0.000 0.185 12.919
ENSG00000122432 E015 0.0000000       1 84526074 84526076 3 +      
ENSG00000122432 E016 0.4904204 0.022854180 0.448846454   1 84527570 84527653 84 + 0.224 0.132 -0.927
ENSG00000122432 E017 0.1271363 0.013177758 1.000000000   1 84532860 84532938 79 + 0.000 0.071 11.718
ENSG00000122432 E018 0.3634701 0.018408441 0.217782063   1 84532939 84532974 36 + 0.224 0.071 -1.927
ENSG00000122432 E019 0.1187032 0.012504788 0.233024957   1 84533622 84533708 87 + 0.126 0.000 -13.210
ENSG00000122432 E020 0.1176306 0.012457656 0.232891811   1 84533709 84533766 58 + 0.126 0.000 -13.210
ENSG00000122432 E021 0.1268540 0.013110686 1.000000000   1 84538845 84538962 118 + 0.000 0.071 11.718
ENSG00000122432 E022 0.3806233 0.017322696 0.345393243   1 84544202 84544304 103 + 0.000 0.185 12.921
ENSG00000122432 E023 0.1176306 0.012457656 0.232891811   1 84545634 84545759 126 + 0.126 0.000 -13.210
ENSG00000122432 E024 2.0051346 0.014396622 0.201769871 0.48415074 1 84548786 84548964 179 + 0.304 0.520 1.189
ENSG00000122432 E025 0.0000000       1 84550432 84550530 99 +      
ENSG00000122432 E026 0.0000000       1 84553035 84553124 90 +      
ENSG00000122432 E027 0.0000000       1 84553125 84553234 110 +      
ENSG00000122432 E028 0.0000000       1 84555910 84555979 70 +      
ENSG00000122432 E029 2.6105472 0.010588122 0.707563256 0.88131758 1 84565861 84567379 1519 + 0.481 0.564 0.395

Help

Please Click HERE to learn more details about the results from DEXseq.