ENSG00000122515

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000309315 ENSG00000122515 No_inf pgKDN_inf ZMIZ2 protein_coding protein_coding 56.68839 56.37168 56.67829 6.764112 4.712654 0.007824212 1.284489 0.000000 3.8534678 0.0000000 0.9581124 8.5937526 0.02347500 0.000000 0.070425 0.070425 6.404469e-06 1.390852e-08 FALSE TRUE
ENST00000478045 ENSG00000122515 No_inf pgKDN_inf ZMIZ2 protein_coding retained_intron 56.68839 56.37168 56.67829 6.764112 4.712654 0.007824212 6.809724 8.413372 4.9022293 1.0808016 1.0422259 -0.7780200 0.12346667 0.153425 0.091175 -0.062250 6.062897e-01 1.390852e-08 FALSE TRUE
ENST00000482322 ENSG00000122515 No_inf pgKDN_inf ZMIZ2 protein_coding retained_intron 56.68839 56.37168 56.67829 6.764112 4.712654 0.007824212 1.827714 5.483142 0.0000000 0.6114017 0.0000000 -9.1014877 0.03375000 0.101250 0.000000 -0.101250 1.390852e-08 1.390852e-08 FALSE FALSE
ENST00000492558 ENSG00000122515 No_inf pgKDN_inf ZMIZ2 protein_coding protein_coding_CDS_not_defined 56.68839 56.37168 56.67829 6.764112 4.712654 0.007824212 12.559276 12.642684 19.1021396 7.6944156 7.4004073 0.5950459 0.19370833 0.186725 0.308550 0.121825 8.347279e-01 1.390852e-08   FALSE
MSTRG.26153.14 ENSG00000122515 No_inf pgKDN_inf ZMIZ2 protein_coding   56.68839 56.37168 56.67829 6.764112 4.712654 0.007824212 3.115422 4.657158 0.7511187 2.0988924 0.7511187 -2.6163508 0.05475000 0.084625 0.012000 -0.072625 3.384403e-01 1.390852e-08 FALSE TRUE
MSTRG.26153.2 ENSG00000122515 No_inf pgKDN_inf ZMIZ2 protein_coding   56.68839 56.37168 56.67829 6.764112 4.712654 0.007824212 1.189702 3.569105 0.0000000 0.3083688 0.0000000 -8.4834549 0.02158333 0.064750 0.000000 -0.064750 9.728637e-07 1.390852e-08 TRUE TRUE
MSTRG.26153.25 ENSG00000122515 No_inf pgKDN_inf ZMIZ2 protein_coding   56.68839 56.37168 56.67829 6.764112 4.712654 0.007824212 3.208577 3.533254 2.6183161 0.3693001 0.6359987 -0.4309361 0.05867500 0.064250 0.049725 -0.014525 8.346783e-01 1.390852e-08 TRUE TRUE
MSTRG.26153.4 ENSG00000122515 No_inf pgKDN_inf ZMIZ2 protein_coding   56.68839 56.37168 56.67829 6.764112 4.712654 0.007824212 3.312695 2.534420 1.9926517 0.8998973 0.7098147 -0.3454255 0.06004167 0.051850 0.033225 -0.018625 9.607463e-01 1.390852e-08 TRUE TRUE
MSTRG.26153.8 ENSG00000122515 No_inf pgKDN_inf ZMIZ2 protein_coding   56.68839 56.37168 56.67829 6.764112 4.712654 0.007824212 8.151426 3.343645 11.2092738 1.3574552 1.3432695 1.7421775 0.14806667 0.062600 0.203200 0.140600 2.768526e-01 1.390852e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000122515 E001 0.1186381 0.0118509540 4.460491e-01   7 44748555 44748563 9 + 0.104 0.000 -10.841
ENSG00000122515 E002 0.6187199 0.0212565640 8.108146e-01 9.303763e-01 7 44748564 44748568 5 + 0.187 0.222 0.308
ENSG00000122515 E003 0.8634869 0.0125317894 8.950819e-01 9.652908e-01 7 44748569 44748571 3 + 0.257 0.276 0.138
ENSG00000122515 E004 1.5996166 0.0084458338 9.550690e-01 9.890593e-01 7 44748572 44748580 9 + 0.418 0.408 -0.055
ENSG00000122515 E005 2.3534330 0.0158307083 4.679855e-01 7.363419e-01 7 44748581 44748631 51 + 0.460 0.564 0.501
ENSG00000122515 E006 0.1186381 0.0118509540 4.460491e-01   7 44748847 44748857 11 + 0.104 0.000 -13.315
ENSG00000122515 E007 0.2362687 0.0157469013 1.849439e-01   7 44748858 44748861 4 + 0.187 0.000 -14.250
ENSG00000122515 E008 0.2362687 0.0157469013 1.849439e-01   7 44748862 44748865 4 + 0.187 0.000 -14.250
ENSG00000122515 E009 0.4702767 0.0161865580 2.874429e-02   7 44748866 44748870 5 + 0.318 0.000 -15.189
ENSG00000122515 E010 0.8253137 0.0123956738 2.138409e-03 2.685909e-02 7 44748871 44748880 10 + 0.460 0.000 -15.952
ENSG00000122515 E011 0.9518207 0.0115807643 1.362522e-02 9.826991e-02 7 44748881 44748895 15 + 0.460 0.087 -3.084
ENSG00000122515 E012 1.4412358 0.0093933135 3.930999e-02 1.920073e-01 7 44748896 44748902 7 + 0.535 0.222 -1.862
ENSG00000122515 E013 1.8057134 0.0075859578 3.009630e-02 1.632152e-01 7 44748903 44748908 6 + 0.598 0.276 -1.736
ENSG00000122515 E014 3.1201629 0.0422779746 3.740136e-03 4.051426e-02 7 44748909 44748961 53 + 0.805 0.368 -2.014
ENSG00000122515 E015 4.3720074 0.0041280846 6.198645e-02 2.501208e-01 7 44748962 44748991 30 + 0.841 0.614 -0.929
ENSG00000122515 E016 0.0000000       7 44749815 44749980 166 +      
ENSG00000122515 E017 0.6004640 0.0150648185 1.179533e-01 3.627584e-01 7 44750972 44751091 120 + 0.318 0.087 -2.277
ENSG00000122515 E018 0.2373413 0.0156791567 1.851113e-01   7 44756179 44756187 9 + 0.187 0.000 -14.250
ENSG00000122515 E019 7.2234151 0.0051384921 4.117782e-01 6.933548e-01 7 44756188 44756204 17 + 0.958 0.872 -0.326
ENSG00000122515 E020 12.2454546 0.0011341964 3.558145e-01 6.455362e-01 7 44756205 44756299 95 + 1.160 1.083 -0.277
ENSG00000122515 E021 19.3397394 0.0015589708 1.449916e-01 4.053481e-01 7 44756425 44756539 115 + 1.358 1.258 -0.350
ENSG00000122515 E022 6.7049890 0.0020826082 3.951492e-02 1.926768e-01 7 44756540 44756946 407 + 0.747 0.965 0.845
ENSG00000122515 E023 8.6833433 0.0015585409 2.587358e-01 5.511753e-01 7 44756947 44756974 28 + 1.040 0.933 -0.399
ENSG00000122515 E024 15.0751412 0.0008754352 7.941691e-04 1.253548e-02 7 44756975 44757042 68 + 1.326 1.075 -0.891
ENSG00000122515 E025 18.9548831 0.0007769948 5.614291e-05 1.466093e-03 7 44757043 44757149 107 + 1.429 1.157 -0.955
ENSG00000122515 E026 0.3627758 0.0167470280 4.745214e-01   7 44757150 44757175 26 + 0.187 0.087 -1.277
ENSG00000122515 E027 2.8734356 0.0418575310 3.371891e-02 1.747537e-01 7 44757176 44757377 202 + 0.371 0.699 1.571
ENSG00000122515 E028 24.9181792 0.0123054293 7.663745e-01 9.093111e-01 7 44757378 44757561 184 + 1.425 1.398 -0.092
ENSG00000122515 E029 40.7987620 0.0034847259 8.772307e-01 9.583262e-01 7 44757848 44758108 261 + 1.614 1.620 0.020
ENSG00000122515 E030 4.4519152 0.0031576303 2.664069e-01 5.598663e-01 7 44759181 44759280 100 + 0.653 0.786 0.546
ENSG00000122515 E031 34.7765272 0.0004375903 9.668871e-01 9.933545e-01 7 44759281 44759460 180 + 1.550 1.550 -0.001
ENSG00000122515 E032 6.3069613 0.0022040341 2.467158e-01 5.373059e-01 7 44759461 44759659 199 + 0.787 0.909 0.475
ENSG00000122515 E033 2.2231863 0.0138740122 5.894718e-01 8.181099e-01 7 44759660 44759686 27 + 0.460 0.537 0.375
ENSG00000122515 E034 4.8642253 0.0031413212 1.201908e-02 9.059917e-02 7 44759687 44759733 47 + 0.568 0.872 1.259
ENSG00000122515 E035 16.5770770 0.0009340406 6.998050e-06 2.509527e-04 7 44759734 44759950 217 + 1.018 1.358 1.209
ENSG00000122515 E036 19.8735538 0.0007384015 1.519088e-04 3.335932e-03 7 44759951 44760150 200 + 1.152 1.410 0.903
ENSG00000122515 E037 17.5421973 0.0074949498 1.137679e-01 3.551106e-01 7 44760151 44760228 78 + 1.192 1.313 0.427
ENSG00000122515 E038 19.4604300 0.0007364142 6.583789e-08 3.994264e-06 7 44760229 44760424 196 + 1.051 1.435 1.358
ENSG00000122515 E039 43.0087706 0.0003195537 9.784816e-01 9.970446e-01 7 44760425 44760593 169 + 1.642 1.638 -0.012
ENSG00000122515 E040 42.4224083 0.0003564798 7.046002e-01 8.799119e-01 7 44761449 44761593 145 + 1.626 1.640 0.051
ENSG00000122515 E041 7.7189638 0.0184627308 9.849768e-03 7.947892e-02 7 44761594 44761694 101 + 0.747 1.042 1.127
ENSG00000122515 E042 39.3700128 0.0003640176 6.400250e-01 8.470115e-01 7 44761695 44761807 113 + 1.591 1.611 0.067
ENSG00000122515 E043 32.1691463 0.0004373617 6.948451e-01 8.753570e-01 7 44761808 44761905 98 + 1.530 1.507 -0.078
ENSG00000122515 E044 32.3936499 0.0026807847 4.709368e-01 7.385080e-01 7 44762881 44762986 106 + 1.543 1.501 -0.146
ENSG00000122515 E045 40.3026551 0.0019564932 2.322136e-01 5.208357e-01 7 44763256 44763413 158 + 1.579 1.636 0.195
ENSG00000122515 E046 0.1268540 0.0124159588 6.468698e-01   7 44763689 44763750 62 + 0.000 0.087 12.196
ENSG00000122515 E047 30.1739492 0.0004886407 4.880816e-01 7.515202e-01 7 44764419 44764486 68 + 1.512 1.473 -0.136
ENSG00000122515 E048 37.3623865 0.0056376795 2.472660e-01 5.378743e-01 7 44764941 44765009 69 + 1.617 1.550 -0.229
ENSG00000122515 E049 71.1857282 0.0071671739 5.596869e-01 8.006355e-01 7 44765335 44765579 245 + 1.871 1.842 -0.097
ENSG00000122515 E050 7.1148863 0.0025718911 4.842342e-04 8.519413e-03 7 44765580 44765710 131 + 0.653 1.033 1.482
ENSG00000122515 E051 3.1279006 0.0047377120 8.675104e-03 7.312958e-02 7 44765711 44765743 33 + 0.371 0.736 1.723
ENSG00000122515 E052 11.3575334 0.0105189183 5.927452e-05 1.532556e-03 7 44765744 44765966 223 + 0.823 1.219 1.460
ENSG00000122515 E053 14.0466236 0.0009517180 4.740458e-04 8.371705e-03 7 44765967 44766056 90 + 0.995 1.274 1.001
ENSG00000122515 E054 6.6200691 0.0096622446 1.099501e-03 1.611865e-02 7 44766057 44766163 107 + 0.627 1.005 1.496
ENSG00000122515 E055 17.8952042 0.0007662988 4.296714e-01 7.078556e-01 7 44766164 44766221 58 + 1.304 1.247 -0.198
ENSG00000122515 E056 33.6398788 0.0077340902 6.349542e-01 8.440079e-01 7 44766222 44766333 112 + 1.553 1.522 -0.108
ENSG00000122515 E057 65.5748749 0.0089319129 7.817189e-01 9.160330e-01 7 44766421 44766663 243 + 1.812 1.825 0.044
ENSG00000122515 E058 278.6598118 0.0003260937 4.735466e-03 4.765071e-02 7 44767516 44769114 1599 + 2.471 2.420 -0.168
ENSG00000122515 E059 4.6501404 0.0069187483 5.781815e-01 8.115034e-01 7 44769115 44769224 110 + 0.787 0.718 -0.277
ENSG00000122515 E060 9.1626164 0.0175776284 3.055006e-01 5.987669e-01 7 44769225 44769454 230 + 1.061 0.954 -0.392
ENSG00000122515 E061 37.2831088 0.0003722878 2.931106e-01 5.867399e-01 7 44769455 44770313 859 + 1.609 1.555 -0.182

Help

Please Click HERE to learn more details about the results from DEXseq.