ENSG00000122574

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000242140 ENSG00000122574 No_inf pgKDN_inf WIPF3 protein_coding protein_coding 13.77502 10.8331 16.87873 0.7603367 1.830431 0.6392834 0.6285611 1.885683 0.0000000 0.6716718 0.0000000 -7.566574 0.05633333 0.169000 0.000000 -0.169000 0.02079346 0.02079346 FALSE TRUE
MSTRG.25971.3 ENSG00000122574 No_inf pgKDN_inf WIPF3 protein_coding   13.77502 10.8331 16.87873 0.7603367 1.830431 0.6392834 6.9995478 4.483034 10.9476757 0.8251504 0.4741094 1.286180 0.51955833 0.427850 0.670075 0.242225 0.42171222 0.02079346 FALSE FALSE
MSTRG.25971.4 ENSG00000122574 No_inf pgKDN_inf WIPF3 protein_coding   13.77502 10.8331 16.87873 0.7603367 1.830431 0.6392834 1.4157646 1.809586 0.5528504 1.0580785 0.3248589 -1.692787 0.12175000 0.171625 0.032300 -0.139325 0.84602002 0.02079346 FALSE TRUE
MSTRG.25971.5 ENSG00000122574 No_inf pgKDN_inf WIPF3 protein_coding   13.77502 10.8331 16.87873 0.7603367 1.830431 0.6392834 4.2552216 2.275864 4.7078315 0.9344590 1.8092753 1.045384 0.26451667 0.195375 0.257025 0.061650 0.85284935 0.02079346 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000122574 E001 0.1186381 0.0118782997 7.072678e-01   7 29806486 29806507 22 + 0.084 0.000 -9.078
ENSG00000122574 E002 0.7452269 0.0142374324 2.504998e-01 5.416531e-01 7 29806508 29806678 171 + 0.154 0.327 1.400
ENSG00000122574 E003 1.7427767 0.0163554774 3.685768e-02 1.848597e-01 7 29834668 29834814 147 + 0.268 0.581 1.722
ENSG00000122574 E004 2.7681905 0.0055739317 9.238558e-02 3.156159e-01 7 29860433 29860563 131 + 0.665 0.429 -1.103
ENSG00000122574 E005 0.9720203 0.0131750234 7.467907e-01 8.998528e-01 7 29871217 29871284 68 + 0.315 0.266 -0.337
ENSG00000122574 E006 0.8795066 0.0125781278 2.076098e-02 1.298229e-01 7 29875789 29875829 41 + 0.084 0.429 2.985
ENSG00000122574 E007 12.8784726 0.0012026514 3.440488e-01 6.353798e-01 7 29875830 29875962 133 + 1.172 1.098 -0.265
ENSG00000122574 E008 11.3342433 0.0013397487 7.122701e-03 6.380265e-02 7 29879009 29879140 132 + 1.178 0.948 -0.837
ENSG00000122574 E009 1.9416908 0.0073998517 6.492467e-01 8.521960e-01 7 29880188 29880273 86 + 0.496 0.429 -0.337
ENSG00000122574 E010 22.6166605 0.0006433988 3.785569e-03 4.091601e-02 7 29883850 29884593 744 + 1.441 1.266 -0.612
ENSG00000122574 E011 17.2093400 0.0008278171 2.628178e-05 7.767021e-04 7 29888068 29888217 150 + 1.369 1.068 -1.067
ENSG00000122574 E012 18.3334125 0.0008496025 2.247587e-01 5.122822e-01 7 29889306 29889407 102 + 1.318 1.238 -0.281
ENSG00000122574 E013 14.2283870 0.0010159623 5.064680e-01 7.651860e-01 7 29904286 29904362 77 + 1.202 1.153 -0.175
ENSG00000122574 E014 5.6051221 0.0026321529 9.641712e-01 9.924389e-01 7 29904363 29906175 1813 + 0.816 0.821 0.021
ENSG00000122574 E015 134.2569916 0.0002258502 1.560146e-09 1.288590e-07 7 29914493 29917061 2569 + 2.077 2.185 0.360

Help

Please Click HERE to learn more details about the results from DEXseq.