ENSG00000122591

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000409763 ENSG00000122591 No_inf pgKDN_inf FAM126A protein_coding protein_coding 20.51396 13.383 26.20065 0.2902215 1.604209 0.9686736 1.9090221 0.0000000 2.9722474 0.0000000 1.7406303 8.2202561 0.07443333 0.000000 0.102750 0.102750 0.56647160 0.03169602 FALSE TRUE
ENST00000440481 ENSG00000122591 No_inf pgKDN_inf FAM126A protein_coding protein_coding 20.51396 13.383 26.20065 0.2902215 1.604209 0.9686736 4.0411187 3.5279322 4.9969646 0.5273358 0.8550383 0.5010299 0.20690833 0.264175 0.188100 -0.076075 0.79226939 0.03169602 FALSE TRUE
ENST00000679789 ENSG00000122591 No_inf pgKDN_inf FAM126A protein_coding nonsense_mediated_decay 20.51396 13.383 26.20065 0.2902215 1.604209 0.9686736 1.2740812 0.3289032 1.7970813 0.3289032 1.7970813 2.4147165 0.05737500 0.025575 0.065025 0.039450 0.97941461 0.03169602 FALSE TRUE
ENST00000680721 ENSG00000122591 No_inf pgKDN_inf FAM126A protein_coding retained_intron 20.51396 13.383 26.20065 0.2902215 1.604209 0.9686736 0.7307201 1.0515253 0.4895969 0.1119540 0.2247932 -1.0873024 0.04231667 0.079175 0.018900 -0.060275 0.25627829 0.03169602 FALSE TRUE
ENST00000681402 ENSG00000122591 No_inf pgKDN_inf FAM126A protein_coding nonsense_mediated_decay 20.51396 13.383 26.20065 0.2902215 1.604209 0.9686736 6.3172740 6.0667710 7.3201356 0.8248896 1.2569820 0.2705350 0.32973333 0.450525 0.289025 -0.161500 0.51422179 0.03169602 FALSE TRUE
ENST00000681766 ENSG00000122591 No_inf pgKDN_inf FAM126A protein_coding protein_coding 20.51396 13.383 26.20065 0.2902215 1.604209 0.9686736 3.9968993 0.0000000 6.1522239 0.0000000 2.0864185 9.2673073 0.16853333 0.000000 0.240375 0.240375 0.03169602 0.03169602 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000122591 E001 0.7338987 0.0142005168 7.505336e-01 0.9016635081 7 22889371 22889693 323 - 0.216 0.264 0.382
ENSG00000122591 E002 0.3527111 0.0275723556 1.664668e-01   7 22890935 22891149 215 - 0.216 0.000 -13.668
ENSG00000122591 E003 0.0000000       7 22919476 22919501 26 -      
ENSG00000122591 E004 0.1268540 0.0123243302 4.121824e-01   7 22920222 22920231 10 - 0.000 0.107 11.839
ENSG00000122591 E005 0.5078857 0.0155776690 2.376968e-02 0.1411350201 7 22920232 22920325 94 - 0.000 0.326 13.711
ENSG00000122591 E006 1.8473751 0.2572367661 6.911651e-01 0.8733089597 7 22934211 22934806 596 - 0.399 0.510 0.573
ENSG00000122591 E007 25.4993942 0.0005537180 2.561213e-05 0.0007610824 7 22934807 22940971 6165 - 1.294 1.538 0.845
ENSG00000122591 E008 0.8868724 0.1104602212 3.416214e-03 0.0380839391 7 22940972 22941083 112 - 0.000 0.471 14.092
ENSG00000122591 E009 0.1265070 0.0123089350 4.121146e-01   7 22941084 22941165 82 - 0.000 0.107 11.839
ENSG00000122591 E010 0.6169598 0.0147405116 4.627963e-01 0.7329898734 7 22941166 22941268 103 - 0.155 0.264 0.967
ENSG00000122591 E011 4.6701765 0.0267844119 1.937922e-01 0.4736480121 7 22941269 22941339 71 - 0.667 0.837 0.687
ENSG00000122591 E012 5.1756077 0.0115630522 4.775217e-02 0.2148907453 7 22941340 22941367 28 - 0.667 0.902 0.938
ENSG00000122591 E013 42.8710320 0.0006045349 5.342665e-05 0.0014090528 7 22941368 22941823 456 - 1.548 1.731 0.622
ENSG00000122591 E014 171.1858838 0.0001192894 1.127825e-04 0.0026209906 7 22941824 22944275 2452 - 2.197 2.275 0.262
ENSG00000122591 E015 18.8176175 0.0156165878 5.713936e-01 0.8076299761 7 22944276 22944508 233 - 1.274 1.319 0.156
ENSG00000122591 E016 14.7579754 0.0010480337 9.442673e-01 0.9845722345 7 22944509 22944650 142 - 1.193 1.199 0.022
ENSG00000122591 E017 88.3264114 0.0002104824 7.939575e-01 0.9214233317 7 22944651 22945571 921 - 1.952 1.945 -0.023
ENSG00000122591 E018 63.3625967 0.0034097392 1.649094e-01 0.4343942091 7 22945572 22945982 411 - 1.832 1.774 -0.197
ENSG00000122591 E019 28.2299654 0.0019804493 4.000213e-01 0.6836253355 7 22945983 22946163 181 - 1.441 1.490 0.169
ENSG00000122591 E020 2.3257078 0.0258538747 7.466184e-01 0.8997455980 7 22946952 22947032 81 - 0.498 0.546 0.229
ENSG00000122591 E021 2.1840083 0.0070589767 6.962363e-01 0.8760405418 7 22947033 22947247 215 - 0.526 0.471 -0.271
ENSG00000122591 E022 16.0836347 0.0038979347 2.938970e-02 0.1611205459 7 22960256 22960415 160 - 1.298 1.133 -0.586
ENSG00000122591 E023 0.0000000       7 22960926 22961048 123 -      
ENSG00000122591 E024 8.2218345 0.0017553772 1.064319e-01 0.3416171243 7 22961235 22961268 34 - 1.027 0.871 -0.587
ENSG00000122591 E025 9.1673956 0.0015728108 1.867472e-02 0.1212942412 7 22961269 22961322 54 - 1.092 0.871 -0.823
ENSG00000122591 E026 14.5594422 0.0009562224 1.293944e-01 0.3816240069 7 22964415 22964531 117 - 1.238 1.124 -0.407
ENSG00000122591 E027 13.6572795 0.0010138562 1.152312e-02 0.0883171409 7 22976210 22976305 96 - 1.243 1.044 -0.715
ENSG00000122591 E028 2.1010540 0.0065792337 8.214622e-02 0.2950305939 7 22976306 22976692 387 - 0.359 0.610 1.256
ENSG00000122591 E029 9.2042195 0.0049815885 1.729523e-01 0.4458894291 7 22976693 22976768 76 - 1.061 0.932 -0.478
ENSG00000122591 E030 5.7066714 0.0359188105 5.565613e-01 0.7988072228 7 22976769 22976808 40 - 0.858 0.780 -0.306
ENSG00000122591 E031 0.7517739 0.0537677817 5.292858e-02 0.2286777162 7 22976809 22976858 50 - 0.084 0.380 2.704
ENSG00000122591 E032 9.6321558 0.0017255058 3.408085e-03 0.0380324670 7 22977341 22977421 81 - 1.128 0.854 -1.017
ENSG00000122591 E033 0.3538994 0.0290596773 1.668575e-01   7 22978164 22978268 105 - 0.216 0.000 -13.661
ENSG00000122591 E034 15.0725132 0.0026863691 1.849825e-03 0.0240579806 7 22978269 22978404 136 - 1.298 1.054 -0.868
ENSG00000122591 E035 9.6356052 0.0066959177 5.057301e-03 0.0500477888 7 22978405 22978448 44 - 1.128 0.854 -1.017
ENSG00000122591 E036 0.2533610 0.0160522179 1.649244e-01   7 22980297 22980320 24 - 0.000 0.193 12.776
ENSG00000122591 E037 1.9924544 0.0162602221 1.285571e-02 0.0945791427 7 22980321 22981663 1343 - 0.269 0.639 1.966
ENSG00000122591 E038 1.3691702 0.0096143052 5.217355e-02 0.2267819408 7 22981664 22983943 2280 - 0.216 0.510 1.797
ENSG00000122591 E039 6.8424234 0.0080465225 1.817753e-03 0.0237152131 7 22983944 22983948 5 - 1.019 0.666 -1.377
ENSG00000122591 E040 15.0730184 0.0008942841 7.250126e-04 0.0116585659 7 22983949 22984045 97 - 1.303 1.044 -0.924
ENSG00000122591 E041 0.7187552 0.0152060790 1.697393e-01 0.4417886680 7 22985548 22985735 188 - 0.316 0.107 -1.941
ENSG00000122591 E042 10.0506061 0.0013958778 7.110273e-02 0.2702255374 7 22991061 22991139 79 - 1.107 0.946 -0.593
ENSG00000122591 E043 8.4300039 0.0015931301 4.945385e-03 0.0492202201 7 23013925 23014130 206 - 1.077 0.800 -1.043

Help

Please Click HERE to learn more details about the results from DEXseq.