ENSG00000122783

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000393114 ENSG00000122783 No_inf pgKDN_inf CYREN protein_coding protein_coding 23.08219 25.23674 21.31406 1.221422 0.6002468 -0.2436151 2.8924828 5.011842 1.5609041 2.9132230 0.9446260 -1.6766214 0.11988333 0.191975 0.073475 -0.118500 9.669662e-01 3.571909e-06 FALSE TRUE
ENST00000424142 ENSG00000122783 No_inf pgKDN_inf CYREN protein_coding protein_coding 23.08219 25.23674 21.31406 1.221422 0.6002468 -0.2436151 5.5223816 2.329541 7.8591081 1.0070256 1.5569104 1.7499747 0.24840833 0.093500 0.375675 0.282175 1.672776e-01 3.571909e-06 FALSE FALSE
ENST00000486115 ENSG00000122783 No_inf pgKDN_inf CYREN protein_coding retained_intron 23.08219 25.23674 21.31406 1.221422 0.6002468 -0.2436151 1.6893570 3.837798 0.0000000 0.6701663 0.0000000 -8.5878893 0.06764167 0.152300 0.000000 -0.152300 3.571909e-06 3.571909e-06   FALSE
ENST00000617987 ENSG00000122783 No_inf pgKDN_inf CYREN protein_coding protein_coding 23.08219 25.23674 21.31406 1.221422 0.6002468 -0.2436151 0.6229494 1.465644 0.1660101 0.2296725 0.1660101 -3.0676147 0.02534167 0.058875 0.007750 -0.051125 1.242090e-01 3.571909e-06 FALSE FALSE
MSTRG.26935.3 ENSG00000122783 No_inf pgKDN_inf CYREN protein_coding   23.08219 25.23674 21.31406 1.221422 0.6002468 -0.2436151 8.2820365 5.756482 8.4962464 2.6448304 1.9563460 0.5608312 0.36783333 0.237950 0.393575 0.155625 7.269196e-01 3.571909e-06 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000122783 E001 2.2600677 0.0083007373 0.005362960 0.05211638 7 135092363 135093378 1016 - 0.246 0.657 2.218
ENSG00000122783 E002 5.8950582 0.0026863544 0.744179988 0.89873493 7 135093379 135094582 1204 - 0.818 0.854 0.137
ENSG00000122783 E003 0.0000000       7 135147977 135148163 187 -      
ENSG00000122783 E004 0.0000000       7 135165779 135165781 3 -      
ENSG00000122783 E005 0.0000000       7 135165782 135165784 3 -      
ENSG00000122783 E006 0.0000000       7 135165785 135165828 44 -      
ENSG00000122783 E007 11.6518113 0.0012863123 0.874032362 0.95698783 7 135165829 135166343 515 - 1.094 1.107 0.048
ENSG00000122783 E008 21.5281259 0.0007235240 0.173524158 0.44678722 7 135166344 135166467 124 - 1.307 1.387 0.277
ENSG00000122783 E009 18.8644981 0.0007814830 0.889898104 0.96327959 7 135166468 135166574 107 - 1.302 1.293 -0.029
ENSG00000122783 E010 9.5204289 0.0021334710 0.306501614 0.59969522 7 135166575 135166599 25 - 1.067 0.978 -0.326
ENSG00000122783 E011 30.4089523 0.0005282057 0.059553320 0.24471991 7 135166600 135166871 272 - 1.541 1.453 -0.301
ENSG00000122783 E012 0.4976273 0.0155524970 0.355855049   7 135167363 135167408 46 - 0.098 0.233 1.481
ENSG00000122783 E013 7.9226303 0.0676305523 0.355509140 0.64530549 7 135167732 135167807 76 - 1.006 0.895 -0.415
ENSG00000122783 E014 3.3708460 0.0087149410 0.006087255 0.05709739 7 135167808 135168179 372 - 0.402 0.775 1.703
ENSG00000122783 E015 0.2533610 0.0161155051 0.269489721   7 135168304 135168595 292 - 0.000 0.168 10.090
ENSG00000122783 E016 0.0000000       7 135168596 135168744 149 -      
ENSG00000122783 E017 0.0000000       7 135168745 135168748 4 -      
ENSG00000122783 E018 0.0000000       7 135168749 135168785 37 -      
ENSG00000122783 E019 0.0000000       7 135168786 135168930 145 -      
ENSG00000122783 E020 0.0000000       7 135168931 135168968 38 -      
ENSG00000122783 E021 0.0000000       7 135168969 135169060 92 -      
ENSG00000122783 E022 0.0000000       7 135169422 135169474 53 -      
ENSG00000122783 E023 1.1137329 0.0142636339 0.370109562 0.65840389 7 135170276 135170398 123 - 0.246 0.383 0.896
ENSG00000122783 E024 7.9893482 0.0392472511 0.767310967 0.90988171 7 135170399 135170651 253 - 0.935 0.967 0.118
ENSG00000122783 E025 2.6609858 0.0063174017 0.059794986 0.24528314 7 135170652 135170803 152 - 0.682 0.424 -1.204

Help

Please Click HERE to learn more details about the results from DEXseq.