ENSG00000123146

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000242786 ENSG00000123146 No_inf pgKDN_inf ADGRE5 protein_coding protein_coding 48.46754 82.44093 25.03431 3.97803 2.239267 -1.719053 6.910996 10.7270805 3.8815564 1.8509449 1.4173938 -1.4641826 0.15355833 0.132775 0.166800 0.034025 1.0000000000 0.0001026123 FALSE TRUE
ENST00000357355 ENSG00000123146 No_inf pgKDN_inf ADGRE5 protein_coding protein_coding 48.46754 82.44093 25.03431 3.97803 2.239267 -1.719053 19.044921 25.6824974 12.9047177 3.6118680 1.7257015 -0.9923310 0.44111667 0.311825 0.521975 0.210150 0.2168835917 0.0001026123 FALSE TRUE
ENST00000358600 ENSG00000123146 No_inf pgKDN_inf ADGRE5 protein_coding protein_coding 48.46754 82.44093 25.03431 3.97803 2.239267 -1.719053 2.842443 3.3333320 1.8696783 1.4373101 0.1061586 -0.8308009 0.06931667 0.042575 0.077150 0.034575 0.7222423414 0.0001026123 FALSE TRUE
ENST00000591737 ENSG00000123146 No_inf pgKDN_inf ADGRE5 protein_coding retained_intron 48.46754 82.44093 25.03431 3.97803 2.239267 -1.719053 1.899879 0.2972928 2.2075040 0.2972928 2.2075040 2.8512511 0.05302500 0.003825 0.071525 0.067700 0.8488773719 0.0001026123   FALSE
MSTRG.14658.18 ENSG00000123146 No_inf pgKDN_inf ADGRE5 protein_coding   48.46754 82.44093 25.03431 3.97803 2.239267 -1.719053 6.943021 19.2761886 0.2398943 3.4276449 0.2398943 -6.2701065 0.09173333 0.230575 0.010700 -0.219875 0.0001026123 0.0001026123 FALSE TRUE
MSTRG.14658.4 ENSG00000123146 No_inf pgKDN_inf ADGRE5 protein_coding   48.46754 82.44093 25.03431 3.97803 2.239267 -1.719053 5.482963 14.2356960 1.2903871 3.1092550 0.8593477 -3.4535130 0.08147500 0.173200 0.047175 -0.126025 0.2078927594 0.0001026123 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000123146 E001 0.0000000       19 14380501 14380616 116 +      
ENSG00000123146 E002 0.4798475 0.0245080691 2.529857e-02   19 14381156 14381364 209 + 0.378 0.053 -3.417
ENSG00000123146 E003 0.7339638 0.0143046917 1.339130e-01 3.888271e-01 19 14381365 14381415 51 + 0.378 0.143 -1.833
ENSG00000123146 E004 0.3812526 0.0158852858 7.215349e-01   19 14381416 14381417 2 + 0.000 0.143 11.453
ENSG00000123146 E005 0.8897676 0.0154264627 1.623947e-01 4.308263e-01 19 14381418 14381434 17 + 0.000 0.281 12.588
ENSG00000123146 E006 1.0073982 0.0154072904 5.175838e-01 7.730433e-01 19 14381435 14381443 9 + 0.165 0.281 0.975
ENSG00000123146 E007 10.7270351 0.0014891814 5.737989e-01 8.090198e-01 19 14381444 14381545 102 + 1.029 0.975 -0.203
ENSG00000123146 E008 13.9235079 0.0010024258 6.090642e-02 2.477331e-01 19 14388450 14388500 51 + 1.211 1.051 -0.573
ENSG00000123146 E009 25.2666251 0.0061674242 1.030613e-01 3.355332e-01 19 14388702 14388818 117 + 1.422 1.305 -0.404
ENSG00000123146 E010 38.9267487 0.0003747267 2.291297e-01 5.177933e-01 19 14390924 14391079 156 + 1.563 1.498 -0.223
ENSG00000123146 E011 0.7621583 0.0132192525 2.248257e-01 5.123700e-01 19 14391080 14391197 118 + 0.000 0.250 12.397
ENSG00000123146 E012 0.3807797 0.0256647495 7.247122e-01   19 14391391 14391492 102 + 0.000 0.143 11.404
ENSG00000123146 E013 0.3727544 0.0168152924 5.934337e-01   19 14396250 14396341 92 + 0.165 0.100 -0.833
ENSG00000123146 E014 23.4120424 0.0005971261 6.386658e-17 1.299842e-14 19 14396342 14396473 132 + 1.648 1.133 -1.787
ENSG00000123146 E015 5.3170070 0.0028721777 2.359121e-02 1.404535e-01 19 14397077 14397223 147 + 0.924 0.653 -1.078
ENSG00000123146 E016 0.7615290 0.0132368415 2.247972e-01 5.123357e-01 19 14397224 14397370 147 + 0.000 0.250 12.397
ENSG00000123146 E017 0.0000000       19 14397414 14397479 66 +      
ENSG00000123146 E018 1.0049786 0.0118027141 5.163285e-01 7.720664e-01 19 14397480 14397657 178 + 0.165 0.281 0.975
ENSG00000123146 E019 12.5290518 0.0343078639 6.625484e-02 2.591894e-01 19 14397658 14397732 75 + 1.198 0.998 -0.724
ENSG00000123146 E020 0.0000000       19 14397733 14397804 72 +      
ENSG00000123146 E021 0.0000000       19 14397805 14397888 84 +      
ENSG00000123146 E022 4.3565925 0.0046418771 3.586682e-01 6.481582e-01 19 14397889 14397935 47 + 0.750 0.628 -0.511
ENSG00000123146 E023 0.0000000       19 14397936 14397980 45 +      
ENSG00000123146 E024 13.9893063 0.0010050208 2.111144e-03 2.662388e-02 19 14398062 14398139 78 + 1.279 1.025 -0.909
ENSG00000123146 E025 0.2533610 0.0160261487 1.000000e+00   19 14398140 14398335 196 + 0.000 0.100 10.895
ENSG00000123146 E026 40.1092269 0.0005299490 9.114878e-01 9.717930e-01 19 14401386 14401563 178 + 1.529 1.524 -0.017
ENSG00000123146 E027 39.0781418 0.0057270316 3.729107e-01 6.605979e-01 19 14401653 14401760 108 + 1.465 1.526 0.208
ENSG00000123146 E028 27.5545655 0.0116340082 4.839712e-01 7.483193e-01 19 14402597 14402862 266 + 1.319 1.379 0.209
ENSG00000123146 E029 0.1265070 0.0123088090 1.000000e+00   19 14404370 14404382 13 + 0.000 0.053 9.948
ENSG00000123146 E030 28.9804000 0.0027668749 6.164474e-01 8.337088e-01 19 14404383 14404562 180 + 1.414 1.382 -0.112
ENSG00000123146 E031 1.5036108 0.0477620208 6.713056e-01 8.636257e-01 19 14404563 14405080 518 + 0.284 0.361 0.489
ENSG00000123146 E032 0.1272623 0.0123545731 1.000000e+00   19 14405379 14405724 346 + 0.000 0.053 9.947
ENSG00000123146 E033 0.1265070 0.0123088090 1.000000e+00   19 14405725 14405747 23 + 0.000 0.053 9.948
ENSG00000123146 E034 49.5772147 0.0003054846 2.273434e-01 5.157238e-01 19 14405748 14405939 192 + 1.563 1.627 0.218
ENSG00000123146 E035 63.9157803 0.0002368784 5.241106e-01 7.772383e-01 19 14406331 14406557 227 + 1.699 1.729 0.101
ENSG00000123146 E036 42.4478430 0.0003421362 1.685603e-01 4.398822e-01 19 14406700 14406766 67 + 1.485 1.564 0.271
ENSG00000123146 E037 47.4108386 0.0003148195 5.335691e-01 7.840590e-01 19 14406869 14406960 92 + 1.569 1.602 0.116
ENSG00000123146 E038 59.2034516 0.0046123690 1.740483e-02 1.156477e-01 19 14407061 14407187 127 + 1.579 1.715 0.460
ENSG00000123146 E039 40.4046640 0.0003409287 9.038521e-03 7.525217e-02 19 14407188 14407229 42 + 1.398 1.557 0.544
ENSG00000123146 E040 66.1081220 0.0002396184 1.107294e-01 3.492966e-01 19 14407908 14408009 102 + 1.678 1.751 0.247
ENSG00000123146 E041 2.4008978 0.0328932463 5.379480e-02 2.307604e-01 19 14408010 14408091 82 + 0.165 0.523 2.337
ENSG00000123146 E042 159.0758393 0.0001359253 3.241299e-01 6.166260e-01 19 14408092 14408725 634 + 2.091 2.119 0.093

Help

Please Click HERE to learn more details about the results from DEXseq.