ENSG00000123609

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000243346 ENSG00000123609 No_inf pgKDN_inf NMI protein_coding protein_coding 40.67745 48.00214 42.97991 1.399454 1.447075 -0.1594012 34.907511 36.882319 40.72785 0.9663537 1.529054 0.1430493 0.8666000 0.772000 0.9492 0.177200 0.02741572 0.02741572 FALSE TRUE
MSTRG.17083.2 ENSG00000123609 No_inf pgKDN_inf NMI protein_coding   40.67745 48.00214 42.97991 1.399454 1.447075 -0.1594012 4.813798 9.552877 1.30183 2.5232625 1.301830 -2.8658637 0.1112667 0.195075 0.0291 -0.165975 0.03020338 0.02741572 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000123609 E001 2.8392938 0.0104469656 0.453449318 0.72614799 2 151270470 151270495 26 - 0.523 0.627 0.470
ENSG00000123609 E002 92.9896922 0.0002048898 0.047138407 0.21328651 2 151270496 151270875 380 - 1.940 1.995 0.185
ENSG00000123609 E003 54.3627893 0.0003350954 0.215249077 0.50102472 2 151271626 151271732 107 - 1.715 1.762 0.160
ENSG00000123609 E004 59.6581854 0.0002746019 0.156857452 0.42325393 2 151275484 151275670 187 - 1.752 1.803 0.173
ENSG00000123609 E005 0.6346136 0.0142694825 0.027996821 0.15631269 2 151275671 151275757 87 - 0.000 0.333 11.177
ENSG00000123609 E006 36.0716450 0.0004352561 0.767898142 0.91019776 2 151275758 151275864 107 - 1.575 1.560 -0.050
ENSG00000123609 E007 0.2458395 0.0163921149 0.928907597   2 151275865 151275881 17 - 0.100 0.090 -0.168
ENSG00000123609 E008 2.1143045 0.0077267753 0.141552361 0.40028773 2 151277255 151278827 1573 - 0.361 0.577 1.095
ENSG00000123609 E009 52.0674636 0.0003967209 0.231082436 0.51953813 2 151278828 151278990 163 - 1.748 1.701 -0.161
ENSG00000123609 E010 36.3367504 0.0082448047 0.204196324 0.48700471 2 151281948 151282038 91 - 1.610 1.535 -0.255
ENSG00000123609 E011 16.3506729 0.0010151750 0.059432480 0.24458716 2 151282039 151282043 5 - 1.305 1.172 -0.470
ENSG00000123609 E012 0.4916139 0.0774527096 0.908908899   2 151282771 151282867 97 - 0.182 0.165 -0.168
ENSG00000123609 E013 30.1364728 0.0005019047 0.007173459 0.06410625 2 151282868 151282954 87 - 1.563 1.422 -0.484
ENSG00000123609 E014 1.7163034 0.0080826743 0.831806235 0.93927831 2 151288891 151289077 187 - 0.450 0.418 -0.168
ENSG00000123609 E015 19.5336268 0.0008047477 0.880899078 0.95997974 2 151289593 151289894 302 - 1.305 1.315 0.032

Help

Please Click HERE to learn more details about the results from DEXseq.