ENSG00000123992

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000273075 ENSG00000123992 No_inf pgKDN_inf DNPEP protein_coding protein_coding 32.68296 33.766 36.03465 5.281509 7.841019 0.09378693 3.746118 4.1845372 2.839636 0.3210695 0.1744132 -0.55773388 0.12479167 0.133925 0.089050 -0.044875 0.78985637 0.0275545 FALSE TRUE
ENST00000373963 ENSG00000123992 No_inf pgKDN_inf DNPEP protein_coding nonsense_mediated_decay 32.68296 33.766 36.03465 5.281509 7.841019 0.09378693 2.809503 0.9895175 3.447219 0.9895175 3.4472186 1.79030816 0.09718333 0.020350 0.139600 0.119250 1.00000000 0.0275545 FALSE TRUE
ENST00000373972 ENSG00000123992 No_inf pgKDN_inf DNPEP protein_coding protein_coding 32.68296 33.766 36.03465 5.281509 7.841019 0.09378693 6.382178 6.2196029 5.531723 2.0765576 3.4020806 -0.16880561 0.23501667 0.220175 0.179525 -0.040650 0.84855848 0.0275545 FALSE TRUE
ENST00000462779 ENSG00000123992 No_inf pgKDN_inf DNPEP protein_coding retained_intron 32.68296 33.766 36.03465 5.281509 7.841019 0.09378693 5.693100 8.2310977 8.848202 5.6509355 8.8482021 0.10417740 0.11559167 0.196425 0.150350 -0.046075 0.84644152 0.0275545   FALSE
ENST00000488051 ENSG00000123992 No_inf pgKDN_inf DNPEP protein_coding retained_intron 32.68296 33.766 36.03465 5.281509 7.841019 0.09378693 1.825605 3.1106627 0.000000 1.0911697 0.0000000 -8.28570862 0.06316667 0.109450 0.000000 -0.109450 0.04114972 0.0275545   FALSE
ENST00000488881 ENSG00000123992 No_inf pgKDN_inf DNPEP protein_coding retained_intron 32.68296 33.766 36.03465 5.281509 7.841019 0.09378693 1.909940 2.2255331 1.260180 0.8982643 0.5347065 -0.81558558 0.06217500 0.080100 0.033250 -0.046850 0.81598425 0.0275545   FALSE
ENST00000490371 ENSG00000123992 No_inf pgKDN_inf DNPEP protein_coding protein_coding_CDS_not_defined 32.68296 33.766 36.03465 5.281509 7.841019 0.09378693 3.635425 4.5739299 4.630838 2.7302684 2.7871429 0.01780042 0.10619167 0.113700 0.151175 0.037475 1.00000000 0.0275545   FALSE
ENST00000523282 ENSG00000123992 No_inf pgKDN_inf DNPEP protein_coding protein_coding 32.68296 33.766 36.03465 5.281509 7.841019 0.09378693 3.348641 0.8720340 5.965087 0.8720340 2.5034768 2.76005362 0.09250000 0.017950 0.164425 0.146475 0.23836037 0.0275545 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000123992 E001 22.0203006 0.0008194907 1.621824e-04 0.0035213947 2 219372043 219373526 1484 - 1.226 1.459 0.812
ENSG00000123992 E002 15.0383796 0.0011005529 3.759883e-06 0.0001468396 2 219373527 219374193 667 - 0.990 1.341 1.254
ENSG00000123992 E003 1.6419785 0.0086135892 9.807740e-04 0.0147922434 2 219374194 219374195 2 - 0.095 0.597 3.599
ENSG00000123992 E004 1.7684855 0.0090084423 5.169481e-04 0.0089736327 2 219374196 219374196 1 - 0.095 0.623 3.715
ENSG00000123992 E005 18.5858114 0.0013017969 7.103101e-02 0.2700469988 2 219374197 219374342 146 - 1.226 1.345 0.418
ENSG00000123992 E006 12.6228413 0.0010925129 7.098843e-01 0.8826576075 2 219374855 219374879 25 - 1.120 1.147 0.098
ENSG00000123992 E007 15.5480051 0.0008826788 9.940609e-01 1.0000000000 2 219374880 219374923 44 - 1.220 1.217 -0.008
ENSG00000123992 E008 21.7491023 0.0006733913 4.136962e-01 0.6943493872 2 219374924 219375022 99 - 1.383 1.331 -0.180
ENSG00000123992 E009 17.8698966 0.0174579012 9.365474e-01 0.9819287896 2 219381335 219381436 102 - 1.274 1.278 0.015
ENSG00000123992 E010 0.6257071 0.2081196485 2.394713e-01 0.5285498116 2 219381437 219381486 50 - 0.095 0.297 2.014
ENSG00000123992 E011 9.5142995 0.0014901362 2.512347e-02 0.1457939701 2 219381545 219381584 40 - 0.906 1.107 0.741
ENSG00000123992 E012 1.6408787 0.1114623397 4.272762e-03 0.0444792796 2 219381585 219381779 195 - 0.095 0.597 3.600
ENSG00000123992 E013 0.7431845 0.0138597310 4.035214e-01 0.6864715349 2 219381792 219381802 11 - 0.172 0.298 1.014
ENSG00000123992 E014 1.3624686 0.0209438160 3.645379e-01 0.6531819797 2 219381803 219381978 176 - 0.295 0.435 0.822
ENSG00000123992 E015 8.1067649 0.0016609185 4.252016e-01 0.7042817841 2 219381979 219381997 19 - 0.919 0.994 0.277
ENSG00000123992 E016 19.7387786 0.0007183379 5.126957e-01 0.7696643467 2 219381998 219382139 142 - 1.296 1.336 0.140
ENSG00000123992 E017 11.1239573 0.0012753102 8.082023e-01 0.9291769382 2 219383131 219383204 74 - 1.095 1.073 -0.081
ENSG00000123992 E018 6.3597457 0.0023249324 8.247529e-01 0.9364284020 2 219383205 219383208 4 - 0.879 0.854 -0.097
ENSG00000123992 E019 6.5125308 0.0021959730 4.601428e-01 0.7315786312 2 219383209 219383214 6 - 0.835 0.910 0.287
ENSG00000123992 E020 11.5944748 0.0011524877 3.918553e-01 0.6769622382 2 219384366 219384443 78 - 1.136 1.064 -0.260
ENSG00000123992 E021 1.3618972 0.0098833598 3.562268e-01 0.6460234042 2 219384444 219384573 130 - 0.295 0.435 0.822
ENSG00000123992 E022 3.9348995 0.0035975070 4.571616e-01 0.7292197881 2 219384586 219385153 568 - 0.644 0.735 0.377
ENSG00000123992 E023 1.9861539 0.0529079750 1.674320e-01 0.4380833403 2 219385154 219385423 270 - 0.346 0.569 1.152
ENSG00000123992 E024 5.8144612 0.0025004601 4.844912e-02 0.2166891908 2 219385424 219385430 7 - 0.932 0.714 -0.852
ENSG00000123992 E025 15.8890038 0.0009103704 4.503928e-03 0.0460676765 2 219385431 219385531 101 - 1.322 1.116 -0.728
ENSG00000123992 E026 10.1719049 0.0016481556 1.034310e-02 0.0820842954 2 219385631 219385658 28 - 1.151 0.923 -0.834
ENSG00000123992 E027 14.1839423 0.0307511486 4.224865e-02 0.2001087598 2 219385659 219385706 48 - 1.279 1.064 -0.769
ENSG00000123992 E028 0.4719759 0.0151660217 4.649791e-02   2 219385707 219385751 45 - 0.295 0.000 -11.319
ENSG00000123992 E029 0.6173655 0.0160081929 6.460484e-01 0.8502109740 2 219385752 219385834 83 - 0.172 0.240 0.599
ENSG00000123992 E030 10.4642345 0.0108736171 1.952340e-01 0.4755084201 2 219385968 219385981 14 - 1.120 0.994 -0.459
ENSG00000123992 E031 22.7596011 0.0006597549 9.636121e-01 0.9923329431 2 219385982 219386098 117 - 1.378 1.373 -0.017
ENSG00000123992 E032 0.4900408 0.0157616092 9.886054e-01   2 219386204 219386285 82 - 0.172 0.174 0.014
ENSG00000123992 E033 17.9251296 0.0007510792 1.821539e-01 0.4582652011 2 219386286 219386411 126 - 1.322 1.230 -0.321
ENSG00000123992 E034 5.3244206 0.0062056173 1.932782e-02 0.1242174545 2 219386665 219386681 17 - 0.919 0.648 -1.085
ENSG00000123992 E035 4.4794043 0.0067415398 3.808359e-02 0.1883194654 2 219386682 219386686 5 - 0.851 0.597 -1.045
ENSG00000123992 E036 9.2629707 0.0017483388 2.780397e-01 0.5712683359 2 219386687 219386778 92 - 1.060 0.960 -0.367
ENSG00000123992 E037 7.6725685 0.0295497139 3.809027e-01 0.6673804492 2 219386892 219386948 57 - 0.990 0.883 -0.401
ENSG00000123992 E038 5.1112174 0.0245868652 2.864960e-01 0.5800471163 2 219386949 219386980 32 - 0.851 0.714 -0.542
ENSG00000123992 E039 6.2041824 0.0179078460 2.666355e-01 0.5600788087 2 219387070 219387163 94 - 0.919 0.790 -0.500
ENSG00000123992 E040 0.0000000       2 219387278 219387575 298 -      
ENSG00000123992 E041 0.7518973 0.0133585417 8.971268e-02 0.3112088692 2 219387576 219387758 183 - 0.095 0.348 2.336
ENSG00000123992 E042 3.1454891 0.0253472928 1.531397e-01 0.4175439640 2 219387759 219387932 174 - 0.711 0.507 -0.903
ENSG00000123992 E043 0.0000000       2 219388702 219388748 47 -      
ENSG00000123992 E044 0.0000000       2 219388834 219388876 43 -      
ENSG00000123992 E045 0.0000000       2 219393611 219393748 138 -      
ENSG00000123992 E046 0.0000000       2 219399440 219399500 61 -      
ENSG00000123992 E047 0.0000000       2 219399866 219399939 74 -      
ENSG00000123992 E048 0.0000000       2 219399940 219400022 83 -      

Help

Please Click HERE to learn more details about the results from DEXseq.