ENSG00000124126

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000371941 ENSG00000124126 No_inf pgKDN_inf PREX1 protein_coding protein_coding 28.17483 31.59727 29.20407 0.6710726 0.6888011 -0.1135934 15.961845 13.720309 20.1923763 0.6671963 0.9315764 0.5571609 0.57494167 0.436150 0.69215 0.256000 0.01051578 0.01051578 FALSE TRUE
ENST00000482556 ENSG00000124126 No_inf pgKDN_inf PREX1 protein_coding nonsense_mediated_decay 28.17483 31.59727 29.20407 0.6710726 0.6888011 -0.1135934 9.486030 13.928178 7.7933487 1.0254078 1.0999029 -0.8368768 0.32977500 0.439475 0.26655 -0.172925 0.19588404 0.01051578 TRUE TRUE
ENST00000620554 ENSG00000124126 No_inf pgKDN_inf PREX1 protein_coding protein_coding 28.17483 31.59727 29.20407 0.6710726 0.6888011 -0.1135934 2.571787 3.728817 0.9727877 0.6666170 0.4090212 -1.9276303 0.09009167 0.117475 0.03260 -0.084875 0.23674046 0.01051578 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000124126 E001 304.5936287 0.0001124173 8.744705e-17 1.759839e-14 20 48624252 48625927 1676 - 2.414 2.540 0.423
ENSG00000124126 E002 29.2038529 0.0139648418 6.849135e-01 8.696630e-01 20 48627548 48627615 68 - 1.466 1.492 0.089
ENSG00000124126 E003 31.1944465 0.0004805718 3.369337e-01 6.288506e-01 20 48627861 48627963 103 - 1.480 1.530 0.173
ENSG00000124126 E004 38.1158380 0.0020869727 8.437528e-01 9.441475e-01 20 48629449 48629621 173 - 1.587 1.596 0.033
ENSG00000124126 E005 24.2356465 0.0005749091 7.711798e-01 9.118300e-01 20 48630728 48630794 67 - 1.411 1.393 -0.061
ENSG00000124126 E006 33.4412090 0.0022344660 9.104054e-01 9.716396e-01 20 48632277 48632391 115 - 1.540 1.534 -0.022
ENSG00000124126 E007 1.6072011 0.0108310071 4.343129e-01 7.116150e-01 20 48632392 48632495 104 - 0.350 0.468 0.646
ENSG00000124126 E008 33.8183958 0.0004576731 9.548094e-01 9.889918e-01 20 48632496 48632639 144 - 1.543 1.540 -0.011
ENSG00000124126 E009 29.7364614 0.0007313861 2.651937e-01 5.583166e-01 20 48634676 48634775 100 - 1.454 1.515 0.207
ENSG00000124126 E010 43.2707318 0.0003629756 7.790418e-01 9.149984e-01 20 48636463 48636683 221 - 1.639 1.651 0.041
ENSG00000124126 E011 13.1197943 0.0011104348 8.586860e-01 9.507384e-01 20 48637711 48637752 42 - 1.142 1.156 0.049
ENSG00000124126 E012 29.8073285 0.0004861984 6.811020e-01 8.682494e-01 20 48639766 48639894 129 - 1.477 1.498 0.075
ENSG00000124126 E013 0.1265070 0.0122641765 5.495930e-01   20 48642113 48642167 55 - 0.000 0.094 8.083
ENSG00000124126 E014 26.3289544 0.0005549222 8.234732e-01 9.359136e-01 20 48642168 48642258 91 - 1.443 1.430 -0.046
ENSG00000124126 E015 20.0521880 0.0007159715 1.325004e-01 3.863896e-01 20 48642407 48642489 83 - 1.269 1.367 0.342
ENSG00000124126 E016 0.7446577 0.0140237148 4.292936e-01 7.075845e-01 20 48642490 48642738 249 - 0.175 0.294 0.968
ENSG00000124126 E017 21.3337118 0.0148146723 7.139548e-01 8.848190e-01 20 48644409 48644497 89 - 1.333 1.362 0.101
ENSG00000124126 E018 29.9451733 0.0005033251 5.474195e-01 7.928873e-01 20 48645851 48646057 207 - 1.473 1.505 0.110
ENSG00000124126 E019 36.9325514 0.0003955747 3.208664e-01 6.138543e-01 20 48649300 48649576 277 - 1.603 1.555 -0.166
ENSG00000124126 E020 33.9621814 0.0004156242 3.944371e-03 4.205094e-02 20 48649996 48650206 211 - 1.614 1.467 -0.502
ENSG00000124126 E021 26.6685108 0.0008770267 1.796083e-02 1.181485e-01 20 48650894 48651055 162 - 1.508 1.371 -0.470
ENSG00000124126 E022 26.7459010 0.0005107485 1.918998e-01 4.716517e-01 20 48651396 48651583 188 - 1.480 1.406 -0.257
ENSG00000124126 E023 14.4081124 0.0009629631 3.035903e-01 5.969318e-01 20 48652586 48652706 121 - 1.226 1.148 -0.277
ENSG00000124126 E024 18.3478805 0.0007114760 4.900262e-03 4.886130e-02 20 48653361 48653497 137 - 1.376 1.184 -0.673
ENSG00000124126 E025 11.3216801 0.0012455317 9.966157e-02 3.298648e-01 20 48655290 48655375 86 - 1.157 1.019 -0.502
ENSG00000124126 E026 3.7912011 0.0094498076 8.180031e-01 9.337724e-01 20 48657040 48657188 149 - 0.696 0.666 -0.125
ENSG00000124126 E027 0.0000000       20 48658136 48658228 93 -      
ENSG00000124126 E028 12.2074291 0.0056108793 8.768117e-02 3.068983e-01 20 48659919 48660061 143 - 1.037 1.184 0.529
ENSG00000124126 E029 11.0075614 0.0053794485 6.150224e-01 8.328886e-01 20 48666283 48666355 73 - 1.101 1.057 -0.160
ENSG00000124126 E030 13.3442786 0.0018719467 3.341227e-03 3.744596e-02 20 48676193 48676268 76 - 1.263 1.029 -0.840
ENSG00000124126 E031 11.0004801 0.0049246277 1.243994e-03 1.769345e-02 20 48679360 48679409 50 - 1.207 0.917 -1.056
ENSG00000124126 E032 15.0534245 0.0009281246 5.025971e-03 4.981086e-02 20 48679651 48679754 104 - 1.302 1.093 -0.744
ENSG00000124126 E033 12.9788953 0.0101168223 7.951036e-01 9.221637e-01 20 48681235 48681335 101 - 1.157 1.133 -0.087
ENSG00000124126 E034 20.4213056 0.0115731831 1.674545e-02 1.128372e-01 20 48688657 48688804 148 - 1.419 1.230 -0.660
ENSG00000124126 E035 20.0490894 0.0022317875 3.440075e-03 3.827873e-02 20 48690947 48691096 150 - 1.415 1.217 -0.690
ENSG00000124126 E036 2.7564718 0.0055384060 2.543980e-03 3.050400e-02 20 48692323 48692671 349 - 0.299 0.729 2.138
ENSG00000124126 E037 16.6185736 0.0008615252 1.868957e-03 2.428338e-02 20 48692672 48692790 119 - 1.348 1.125 -0.786
ENSG00000124126 E038 17.4906226 0.0017712508 6.064984e-03 5.694547e-02 20 48700753 48700886 134 - 1.358 1.163 -0.684
ENSG00000124126 E039 18.2119674 0.0027079053 4.994290e-03 4.956063e-02 20 48708260 48708421 162 - 1.376 1.177 -0.698
ENSG00000124126 E040 12.2780546 0.0344847131 1.888967e-01 4.674875e-01 20 48726290 48726391 102 - 1.193 1.048 -0.522
ENSG00000124126 E041 12.4678069 0.0477532417 9.204592e-01 9.752146e-01 20 48734546 48734650 105 - 1.142 1.117 -0.087
ENSG00000124126 E042 10.3169030 0.0709810382 5.604611e-01 8.010151e-01 20 48745025 48745147 123 - 1.017 1.084 0.244
ENSG00000124126 E043 7.6349117 0.0043519515 3.629708e-01 6.520513e-01 20 48747809 48747880 72 - 0.886 0.976 0.342
ENSG00000124126 E044 9.9064614 0.0034431092 5.277721e-01 7.796198e-01 20 48827642 48827999 358 - 1.066 1.009 -0.211

Help

Please Click HERE to learn more details about the results from DEXseq.