ENSG00000124214

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000340954 ENSG00000124214 No_inf pgKDN_inf STAU1 protein_coding protein_coding 40.74622 38.52923 43.13677 1.199313 0.4328539 0.1629248 3.373985 4.467184 2.937417 0.9710814 0.4600636 -0.60314052 0.08329167 0.115175 0.067875 -0.047300 0.783288932 0.005110641 FALSE TRUE
ENST00000347458 ENSG00000124214 No_inf pgKDN_inf STAU1 protein_coding protein_coding 40.74622 38.52923 43.13677 1.199313 0.4328539 0.1629248 2.435794 2.818697 2.220768 1.0681816 2.2207678 -0.34259711 0.06165000 0.074550 0.051450 -0.023100 0.310696376 0.005110641 FALSE TRUE
ENST00000360426 ENSG00000124214 No_inf pgKDN_inf STAU1 protein_coding protein_coding 40.74622 38.52923 43.13677 1.199313 0.4328539 0.1629248 7.785212 0.000000 11.895646 0.0000000 4.1624051 10.21743023 0.18375000 0.000000 0.275225 0.275225 0.005110641 0.005110641 FALSE TRUE
ENST00000371828 ENSG00000124214 No_inf pgKDN_inf STAU1 protein_coding protein_coding 40.74622 38.52923 43.13677 1.199313 0.4328539 0.1629248 11.601955 14.777818 11.347284 1.2778933 2.4511173 -0.38079133 0.29068333 0.386675 0.264175 -0.122500 0.567449361 0.005110641 FALSE TRUE
ENST00000371856 ENSG00000124214 No_inf pgKDN_inf STAU1 protein_coding protein_coding 40.74622 38.52923 43.13677 1.199313 0.4328539 0.1629248 2.071266 2.540677 1.433053 0.6076114 0.4367717 -0.82175535 0.05115000 0.065525 0.033325 -0.032200 0.694254809 0.005110641 FALSE TRUE
MSTRG.18379.3 ENSG00000124214 No_inf pgKDN_inf STAU1 protein_coding   40.74622 38.52923 43.13677 1.199313 0.4328539 0.1629248 13.026649 13.500899 12.675206 1.8875377 1.1528724 -0.09097677 0.31835833 0.347425 0.293300 -0.054125 0.834255812 0.005110641 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000124214 E001 0.1268540 1.234135e-02 0.553668855   20 49113339 49113340 2 - 0.000 0.094 8.359
ENSG00000124214 E002 1.7674501 1.709750e-01 0.006290504 0.05839450 20 49113341 49113353 13 - 0.096 0.617 3.661
ENSG00000124214 E003 16.7705284 8.613831e-04 0.039021176 0.19128249 20 49113354 49113522 169 - 1.166 1.313 0.519
ENSG00000124214 E004 347.1635905 8.739664e-05 0.832968098 0.93976156 20 49113523 49114893 1371 - 2.540 2.543 0.010
ENSG00000124214 E005 26.3740927 5.291393e-04 0.586872113 0.81685619 20 49115782 49115867 86 - 1.420 1.451 0.108
ENSG00000124214 E006 33.8290181 4.318731e-04 0.997447941 1.00000000 20 49117126 49117248 123 - 1.541 1.542 0.002
ENSG00000124214 E007 30.4379137 5.241223e-04 0.504047494 0.76334821 20 49117777 49117850 74 - 1.478 1.514 0.123
ENSG00000124214 E008 30.6037192 6.274179e-04 0.725234753 0.88973083 20 49117851 49117935 85 - 1.509 1.490 -0.063
ENSG00000124214 E009 46.8831116 3.023886e-04 0.333543744 0.62556082 20 49117936 49118096 161 - 1.657 1.699 0.142
ENSG00000124214 E010 26.0428324 5.549777e-04 0.241927067 0.53155556 20 49118333 49118408 76 - 1.395 1.462 0.233
ENSG00000124214 E011 31.9318504 4.940636e-04 0.504074149 0.76334821 20 49119982 49120128 147 - 1.535 1.501 -0.117
ENSG00000124214 E012 29.1110031 1.770547e-03 0.022305612 0.13584359 20 49123092 49123229 138 - 1.541 1.413 -0.441
ENSG00000124214 E013 12.8435649 1.502439e-02 0.735249934 0.89506115 20 49123230 49123235 6 - 1.158 1.124 -0.122
ENSG00000124214 E014 36.4039709 4.609931e-04 0.779663462 0.91504130 20 49124375 49124587 213 - 1.565 1.579 0.048
ENSG00000124214 E015 2.3738669 6.748119e-03 0.012064261 0.09085086 20 49124588 49124605 18 - 0.299 0.665 1.867
ENSG00000124214 E016 0.2444846 1.638762e-02 0.982575828   20 49132634 49132720 87 - 0.096 0.094 -0.040
ENSG00000124214 E017 18.4377025 7.795209e-04 0.218189010 0.50464600 20 49135833 49135931 99 - 1.329 1.247 -0.289
ENSG00000124214 E018 27.7440148 8.743769e-04 0.006466562 0.05953697 20 49151582 49151747 166 - 1.532 1.379 -0.525
ENSG00000124214 E019 23.9577460 5.788565e-04 0.439777013 0.71565879 20 49153933 49154071 139 - 1.420 1.375 -0.157
ENSG00000124214 E020 0.3646686 2.507913e-01 0.620786832   20 49158437 49158497 61 - 0.175 0.094 -1.040
ENSG00000124214 E021 0.7363505 1.421570e-02 0.971541495 0.99453344 20 49158939 49159146 208 - 0.242 0.237 -0.040
ENSG00000124214 E022 3.3399685 4.255233e-03 0.205674617 0.48903064 20 49165997 49166285 289 - 0.542 0.708 0.726
ENSG00000124214 E023 14.9862282 1.281349e-02 0.623033241 0.83769753 20 49174195 49174269 75 - 1.180 1.223 0.149
ENSG00000124214 E024 2.9554138 4.851925e-03 0.459940195 0.73151732 20 49179122 49179244 123 - 0.542 0.641 0.446
ENSG00000124214 E025 15.9085888 2.925236e-03 0.618645907 0.83506979 20 49188116 49188367 252 - 1.246 1.210 -0.128

Help

Please Click HERE to learn more details about the results from DEXseq.