ENSG00000124299

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000244137 ENSG00000124299 No_inf pgKDN_inf PEPD protein_coding protein_coding 32.27951 45.68347 30.58798 1.969664 0.5247683 -0.5785516 27.0219581 34.664194 28.11549 2.499238 0.9736706 -0.301984 0.85773333 0.763125 0.9189 0.155775 0.1928530 0.0371857 FALSE TRUE
ENST00000591968 ENSG00000124299 No_inf pgKDN_inf PEPD protein_coding protein_coding_CDS_not_defined 32.27951 45.68347 30.58798 1.969664 0.5247683 -0.5785516 1.6932085 5.079625 0.00000 2.153656 0.0000000 -8.991416 0.03549167 0.106475 0.0000 -0.106475 0.0371857 0.0371857 FALSE TRUE
ENST00000698431 ENSG00000124299 No_inf pgKDN_inf PEPD protein_coding nonsense_mediated_decay 32.27951 45.68347 30.58798 1.969664 0.5247683 -0.5785516 0.8805095 2.641529 0.00000 2.641529 0.0000000 -8.050680 0.01952500 0.058575 0.0000 -0.058575 0.9092334 0.0371857 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000124299 E001 0.2533610 0.0159482802 0.45455760   19 33386950 33386951 2 - 0.000 0.142 11.200
ENSG00000124299 E002 1.1334667 0.0122085571 0.07131826 0.27055491 19 33386952 33386954 3 - 0.118 0.405 2.308
ENSG00000124299 E003 1.7596123 0.0079871803 0.04944967 0.21927307 19 33386955 33386964 10 - 0.210 0.520 1.893
ENSG00000124299 E004 4.3897979 0.0040493170 0.00699740 0.06303621 19 33386965 33386979 15 - 0.457 0.819 1.581
ENSG00000124299 E005 6.7510373 0.0034194062 0.01276510 0.09411910 19 33386980 33386997 18 - 0.675 0.958 1.116
ENSG00000124299 E006 11.7023669 0.0012346097 0.03067297 0.16473971 19 33386998 33387023 26 - 0.958 1.149 0.695
ENSG00000124299 E007 21.1251114 0.0007710156 0.02334451 0.13954876 19 33387024 33387107 84 - 1.227 1.379 0.531
ENSG00000124299 E008 64.3220985 0.0002660266 0.29562097 0.58869829 19 33387108 33387348 241 - 1.774 1.812 0.129
ENSG00000124299 E009 41.8660341 0.0020657819 0.93117283 0.97997727 19 33387349 33387481 133 - 1.614 1.617 0.011
ENSG00000124299 E010 0.4999558 0.0152390114 0.60050538 0.82509275 19 33387482 33387654 173 - 0.118 0.198 0.893
ENSG00000124299 E011 0.6186549 0.2217858279 0.96522412 0.99272752 19 33387655 33387744 90 - 0.210 0.198 -0.107
ENSG00000124299 E012 0.3809057 0.0159396105 0.23305089   19 33387745 33387889 145 - 0.000 0.198 14.084
ENSG00000124299 E013 27.5665754 0.0121996603 0.69261196 0.87418975 19 33387890 33387958 69 - 1.423 1.450 0.090
ENSG00000124299 E014 38.0288202 0.0126449924 0.90900337 0.97113908 19 33387959 33388081 123 - 1.580 1.573 -0.024
ENSG00000124299 E015 3.4927566 0.0067671563 0.14268615 0.40209178 19 33388082 33389120 1039 - 0.502 0.703 0.893
ENSG00000124299 E016 0.9811550 0.0120392033 0.50553122 0.76437680 19 33390201 33390316 116 - 0.351 0.248 -0.692
ENSG00000124299 E017 28.5863107 0.0013315715 0.33858956 0.63027074 19 33391295 33391388 94 - 1.489 1.434 -0.189
ENSG00000124299 E018 27.3559300 0.0005626055 0.33312102 0.62518439 19 33391389 33391479 91 - 1.472 1.416 -0.193
ENSG00000124299 E019 0.5076336 0.0157091947 0.12479087 0.37445143 19 33395110 33395148 39 - 0.000 0.248 14.463
ENSG00000124299 E020 0.7450399 0.0344320312 0.80717717 0.92887002 19 33396090 33396155 66 - 0.210 0.248 0.308
ENSG00000124299 E021 0.2530140 0.2574171892 0.51585147   19 33399542 33399829 288 - 0.000 0.141 13.045
ENSG00000124299 E022 0.0000000       19 33400209 33400368 160 -      
ENSG00000124299 E023 0.2372762 0.2121611409 0.15113555   19 33400369 33400711 343 - 0.210 0.000 -14.785
ENSG00000124299 E024 0.8696843 0.3045759090 0.67371645 0.86492164 19 33400712 33401720 1009 - 0.210 0.293 0.631
ENSG00000124299 E025 29.5217718 0.0040623318 0.95165772 0.98784548 19 33401721 33401789 69 - 1.472 1.467 -0.016
ENSG00000124299 E026 20.4014094 0.0063820335 0.87155036 0.95589549 19 33401790 33401807 18 - 1.307 1.319 0.040
ENSG00000124299 E027 25.1062113 0.0067121277 0.73600728 0.89521916 19 33401808 33401838 31 - 1.386 1.409 0.079
ENSG00000124299 E028 22.9722163 0.0049392052 0.90717575 0.97049721 19 33401839 33401869 31 - 1.369 1.361 -0.029
ENSG00000124299 E029 23.1299245 0.0032238522 0.15495997 0.42055105 19 33411672 33411749 78 - 1.423 1.331 -0.321
ENSG00000124299 E030 0.0000000       19 33411750 33411800 51 -      
ENSG00000124299 E031 0.0000000       19 33413552 33413574 23 -      
ENSG00000124299 E032 27.6843052 0.0005166406 0.80639242 0.92840303 19 33413575 33413643 69 - 1.433 1.447 0.045
ENSG00000124299 E033 0.0000000       19 33413800 33413932 133 -      
ENSG00000124299 E034 0.0000000       19 33415685 33415842 158 -      
ENSG00000124299 E035 0.1187032 0.0118403798 0.32686371   19 33452731 33453284 554 - 0.118 0.000 -14.432
ENSG00000124299 E036 0.3729107 0.1860390758 1.00000000   19 33460103 33461024 922 - 0.118 0.142 0.308
ENSG00000124299 E037 0.0000000       19 33462522 33462643 122 -      
ENSG00000124299 E038 0.0000000       19 33462644 33462717 74 -      
ENSG00000124299 E039 0.1271363 0.0123317901 0.91056746   19 33462718 33462945 228 - 0.000 0.076 12.599
ENSG00000124299 E040 0.2536433 0.0160326965 0.45437996   19 33462946 33462950 5 - 0.000 0.142 13.539
ENSG00000124299 E041 0.2536433 0.0160326965 0.45437996   19 33462951 33462994 44 - 0.000 0.142 13.539
ENSG00000124299 E042 25.6239380 0.0005544170 0.36436352 0.65314365 19 33462995 33463041 47 - 1.375 1.428 0.184
ENSG00000124299 E043 25.1034715 0.0005925440 0.58641802 0.81660484 19 33463987 33464062 76 - 1.381 1.412 0.110
ENSG00000124299 E044 0.0000000       19 33477080 33477299 220 -      
ENSG00000124299 E045 16.8225891 0.0008429966 0.58534617 0.81581741 19 33478046 33478090 45 - 1.211 1.249 0.136
ENSG00000124299 E046 0.0000000       19 33486903 33487080 178 -      
ENSG00000124299 E047 0.0000000       19 33487250 33487387 138 -      
ENSG00000124299 E048 18.2864940 0.0108120413 0.79706433 0.92339958 19 33489996 33490057 62 - 1.258 1.277 0.066
ENSG00000124299 E049 14.7667144 0.0030111199 0.27237604 0.56606790 19 33493290 33493314 25 - 1.235 1.149 -0.305
ENSG00000124299 E050 15.2756410 0.0181100609 0.50129354 0.76129881 19 33493315 33493337 23 - 1.235 1.172 -0.223
ENSG00000124299 E051 0.0000000       19 33493338 33493420 83 -      
ENSG00000124299 E052 15.1313498 0.0086428273 0.25770427 0.54995326 19 33500938 33501001 64 - 1.250 1.155 -0.338
ENSG00000124299 E053 0.0000000       19 33501002 33501511 510 -      
ENSG00000124299 E054 19.7060882 0.0008045782 0.35415974 0.64387688 19 33511028 33511115 88 - 1.339 1.277 -0.219
ENSG00000124299 E055 18.2023192 0.0009176635 0.16303017 0.43167899 19 33511116 33511155 40 - 1.327 1.230 -0.339
ENSG00000124299 E056 0.0000000       19 33511156 33511521 366 -      
ENSG00000124299 E057 29.1822596 0.0130102399 0.01628097 0.11082387 19 33512593 33512776 184 - 1.562 1.396 -0.571
ENSG00000124299 E058 0.0000000       19 33515006 33515199 194 -      
ENSG00000124299 E059 0.0000000       19 33521637 33521671 35 -      
ENSG00000124299 E060 0.0000000       19 33521672 33521743 72 -      
ENSG00000124299 E061 7.2012947 0.0022769048 0.01412921 0.10079958 19 33521744 33521823 80 - 1.040 0.792 -0.937

Help

Please Click HERE to learn more details about the results from DEXseq.