ENSG00000124406

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264449 ENSG00000124406 No_inf pgKDN_inf ATP8A1 protein_coding protein_coding 5.851774 9.357849 4.900689 1.117046 0.3856247 -0.9317925 1.8088607 2.8731948 0.5788752 0.09516562 0.5788752 -2.2916345 0.36215833 0.320000 0.134425 -0.185575 0.285364926 0.009785633 FALSE TRUE
ENST00000504024 ENSG00000124406 No_inf pgKDN_inf ATP8A1 protein_coding nonsense_mediated_decay 5.851774 9.357849 4.900689 1.117046 0.3856247 -0.9317925 0.4897110 1.4691331 0.0000000 1.46913314 0.0000000 -7.2086081 0.03901667 0.117050 0.000000 -0.117050 0.934377312 0.009785633   FALSE
ENST00000504510 ENSG00000124406 No_inf pgKDN_inf ATP8A1 protein_coding retained_intron 5.851774 9.357849 4.900689 1.117046 0.3856247 -0.9317925 0.5097492 0.5698322 0.7199272 0.39431996 0.4163486 0.3321173 0.08520833 0.065925 0.129825 0.063900 0.852591792 0.009785633   FALSE
ENST00000514372 ENSG00000124406 No_inf pgKDN_inf ATP8A1 protein_coding nonsense_mediated_decay 5.851774 9.357849 4.900689 1.117046 0.3856247 -0.9317925 2.3575371 4.1062818 1.8835450 0.37138311 0.2226290 -1.1202520 0.38830833 0.456500 0.400350 -0.056150 0.888195796 0.009785633 FALSE TRUE
ENST00000700470 ENSG00000124406 No_inf pgKDN_inf ATP8A1 protein_coding protein_coding 5.851774 9.357849 4.900689 1.117046 0.3856247 -0.9317925 0.5727804 0.0000000 1.7183412 0.00000000 0.6031342 7.4332443 0.11180833 0.000000 0.335425 0.335425 0.009785633 0.009785633 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000124406 E001 0.1271363 0.0123144627 1.000000000   4 42408373 42408376 4 - 0.000 0.073 9.334
ENSG00000124406 E002 0.1271363 0.0123144627 1.000000000   4 42408377 42408381 5 - 0.000 0.073 11.579
ENSG00000124406 E003 150.9688596 0.0001581699 0.013710015 0.09867039 4 42408382 42412974 4593 - 2.130 2.173 0.142
ENSG00000124406 E004 2.8263966 0.0351815061 0.480412172 0.74583273 4 42412975 42413013 39 - 0.632 0.528 -0.468
ENSG00000124406 E005 3.3367703 0.0564310781 0.876874895 0.95824250 4 42414627 42414718 92 - 0.632 0.613 -0.081
ENSG00000124406 E006 0.1271363 0.0123144627 1.000000000   4 42414719 42415147 429 - 0.000 0.073 11.579
ENSG00000124406 E007 3.9824231 0.0692263143 0.494545304 0.75596051 4 42422807 42422899 93 - 0.597 0.716 0.507
ENSG00000124406 E008 5.5702733 0.0054925035 0.989771997 1.00000000 4 42423617 42423705 89 - 0.796 0.799 0.011
ENSG00000124406 E009 5.1829760 0.0041080384 0.522401778 0.77595298 4 42443565 42443672 108 - 0.818 0.745 -0.291
ENSG00000124406 E010 3.0763190 0.0044635917 0.394801217 0.67960559 4 42444578 42444634 57 - 0.664 0.551 -0.499
ENSG00000124406 E011 3.0555850 0.0047343350 0.098362457 0.32719136 4 42446583 42446644 62 - 0.722 0.504 -0.963
ENSG00000124406 E012 2.0786472 0.0068326960 0.150738334 0.41346291 4 42451981 42452059 79 - 0.597 0.391 -1.017
ENSG00000124406 E013 2.8309832 0.0049886400 0.443756460 0.71843570 4 42455297 42455419 123 - 0.632 0.528 -0.469
ENSG00000124406 E014 0.2533610 0.0161094995 0.521620861   4 42455420 42455433 14 - 0.000 0.135 12.484
ENSG00000124406 E015 1.2163215 0.0103447787 0.121855318 0.36939510 4 42455525 42455599 75 - 0.473 0.238 -1.432
ENSG00000124406 E016 0.0000000       4 42459358 42459532 175 -      
ENSG00000124406 E017 1.5959374 0.0084939908 0.442834959 0.71803736 4 42464690 42464800 111 - 0.473 0.357 -0.625
ENSG00000124406 E018 3.5856217 0.0112033964 0.897297396 0.96613081 4 42464893 42465076 184 - 0.632 0.650 0.079
ENSG00000124406 E019 0.7360985 0.0140920545 0.476155260 0.74273941 4 42485496 42485528 33 - 0.298 0.190 -0.847
ENSG00000124406 E020 3.6097275 0.0040512727 0.356794639 0.64661835 4 42485529 42485668 140 - 0.559 0.684 0.545
ENSG00000124406 E021 3.0187353 0.0048040237 0.010497788 0.08290931 4 42503450 42503514 65 - 0.298 0.684 1.960
ENSG00000124406 E022 6.1717393 0.0023858301 0.526607980 0.77887569 4 42507016 42507154 139 - 0.879 0.811 -0.262
ENSG00000124406 E023 5.8675614 0.0027110314 0.070258986 0.26818133 4 42522160 42522299 140 - 0.664 0.879 0.863
ENSG00000124406 E024 2.6276041 0.0060279743 0.097216234 0.32475217 4 42524763 42524847 85 - 0.364 0.613 1.240
ENSG00000124406 E025 1.4847584 0.0095790103 0.866731993 0.95412343 4 42543917 42543986 70 - 0.364 0.391 0.153
ENSG00000124406 E026 0.9781014 0.0117179962 0.411943683 0.69348182 4 42549013 42549062 50 - 0.364 0.238 -0.847
ENSG00000124406 E027 1.5783471 0.0084988244 0.060906689 0.24773313 4 42551198 42551280 83 - 0.559 0.282 -1.525
ENSG00000124406 E028 2.1914292 0.0262781628 0.037868089 0.18777030 4 42552505 42552554 50 - 0.664 0.357 -1.499
ENSG00000124406 E029 3.1887576 0.0050013585 0.139009266 0.39647413 4 42552555 42552610 56 - 0.722 0.528 -0.847
ENSG00000124406 E030 2.8251926 0.0059010033 0.237581155 0.52655925 4 42555968 42556040 73 - 0.664 0.504 -0.722
ENSG00000124406 E031 0.0000000       4 42556041 42556235 195 -      
ENSG00000124406 E032 0.0000000       4 42569161 42569205 45 -      
ENSG00000124406 E033 2.8226727 0.0330156053 0.266273984 0.55976714 4 42574619 42574707 89 - 0.664 0.504 -0.722
ENSG00000124406 E034 2.3489668 0.0065836560 0.914688297 0.97309389 4 42575622 42575699 78 - 0.518 0.504 -0.069
ENSG00000124406 E035 2.6662753 0.0055261536 0.008343501 0.07113474 4 42578260 42578387 128 - 0.748 0.391 -1.654
ENSG00000124406 E036 2.6650466 0.0053574860 0.008286996 0.07078727 4 42579813 42579978 166 - 0.748 0.391 -1.654
ENSG00000124406 E037 1.8475992 0.0081446220 0.731236714 0.89325394 4 42581621 42581681 61 - 0.473 0.422 -0.262
ENSG00000124406 E038 1.3572751 0.0645633289 0.956372848 0.98965422 4 42581682 42581691 10 - 0.364 0.357 -0.040
ENSG00000124406 E039 1.6212414 0.0351659820 0.349152325 0.63959930 4 42581692 42581732 41 - 0.298 0.451 0.890
ENSG00000124406 E040 2.4924685 0.0423283955 0.342428844 0.63385240 4 42586349 42586476 128 - 0.422 0.573 0.738
ENSG00000124406 E041 1.7405066 0.0193649968 0.580872909 0.81323083 4 42588260 42588329 70 - 0.364 0.451 0.475
ENSG00000124406 E042 1.0969542 0.0116037233 0.229804607 0.51831256 4 42588330 42588617 288 - 0.422 0.238 -1.169
ENSG00000124406 E043 0.2435110 0.0163458365 0.645963536   4 42590811 42590884 74 - 0.123 0.073 -0.847
ENSG00000124406 E044 0.8791596 0.0122373069 0.212510955 0.49771508 4 42594289 42594362 74 - 0.123 0.321 1.738
ENSG00000124406 E045 0.8734659 0.3394009143 0.758297301 0.90514365 4 42600478 42600518 41 - 0.219 0.282 0.475
ENSG00000124406 E046 0.9904673 0.0668909676 0.923415030 0.97664317 4 42616033 42616078 46 - 0.298 0.282 -0.110
ENSG00000124406 E047 1.8527556 0.0163897492 0.736575256 0.89552647 4 42624536 42624634 99 - 0.473 0.422 -0.262
ENSG00000124406 E048 0.0000000       4 42625141 42625613 473 -      
ENSG00000124406 E049 0.8702833 0.0134150632 0.691354638 0.87346907 4 42625614 42625713 100 - 0.219 0.282 0.475
ENSG00000124406 E050 0.0000000       4 42625714 42626994 1281 -      
ENSG00000124406 E051 1.1173475 0.0283894428 0.888006423 0.96253343 4 42626995 42627109 115 - 0.298 0.321 0.153
ENSG00000124406 E052 0.8717330 0.1963753056 0.810413890 0.93011861 4 42656825 42657121 297 - 0.219 0.282 0.475

Help

Please Click HERE to learn more details about the results from DEXseq.