ENSG00000124459

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000269973 ENSG00000124459 No_inf pgKDN_inf ZNF45 protein_coding protein_coding 12.55881 19.91626 5.109685 9.090104 0.636468 -1.960544 1.5617512 0.3214865 2.6102468 0.1277827 0.41063400 2.9826805 0.3279667 0.046575 0.541150 0.494575 0.01542554 0.01542554 FALSE TRUE
ENST00000588140 ENSG00000124459 No_inf pgKDN_inf ZNF45 protein_coding protein_coding 12.55881 19.91626 5.109685 9.090104 0.636468 -1.960544 0.1734276 0.0000000 0.5202827 0.0000000 0.52028270 5.7286898 0.0248750 0.000000 0.074625 0.074625 0.70132455 0.01542554 FALSE FALSE
ENST00000615985 ENSG00000124459 No_inf pgKDN_inf ZNF45 protein_coding protein_coding 12.55881 19.91626 5.109685 9.090104 0.636468 -1.960544 1.4781007 2.1366443 1.3641731 0.1154942 0.46935607 -0.6435194 0.2248500 0.303550 0.260750 -0.042800 1.00000000 0.01542554 FALSE TRUE
MSTRG.15269.2 ENSG00000124459 No_inf pgKDN_inf ZNF45 protein_coding   12.55881 19.91626 5.109685 9.090104 0.636468 -1.960544 1.1663797 1.7140434 0.4230256 0.1696617 0.07241813 -1.9932720 0.1813000 0.208375 0.084100 -0.124275 0.83467830 0.01542554 FALSE TRUE
MSTRG.15269.6 ENSG00000124459 No_inf pgKDN_inf ZNF45 protein_coding   12.55881 19.91626 5.109685 9.090104 0.636468 -1.960544 8.0472840 15.6028017 0.0000000 9.0102886 0.00000000 -10.6085137 0.2210583 0.437525 0.000000 -0.437525 0.76092327 0.01542554   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000124459 E001 0.3621491 0.0170645975 0.551073416   19 43912624 43912630 7 - 0.177 0.093 -1.078
ENSG00000124459 E002 12.1125786 0.0178381781 0.619111157 0.83533591 19 43912631 43913128 498 - 1.141 1.095 -0.165
ENSG00000124459 E003 46.7336650 0.0003653385 0.596497622 0.82265330 19 43913129 43914940 1812 - 1.670 1.685 0.051
ENSG00000124459 E004 5.0180133 0.0037475832 0.746354031 0.89967291 19 43914941 43915200 260 - 0.798 0.761 -0.148
ENSG00000124459 E005 2.2137472 0.0579204880 0.741266895 0.89736687 19 43918870 43918962 93 - 0.479 0.529 0.244
ENSG00000124459 E006 2.8136069 0.0065829318 0.744592578 0.89879857 19 43919573 43919699 127 - 0.604 0.559 -0.203
ENSG00000124459 E007 0.6162316 0.1501588866 0.704334075 0.87985070 19 43919700 43919739 40 - 0.177 0.234 0.508
ENSG00000124459 E008 1.2255422 0.0123006637 0.934923195 0.98127141 19 43922171 43922217 47 - 0.354 0.341 -0.078
ENSG00000124459 E009 0.1271363 0.0125051089 0.565969742   19 43922218 43922287 70 - 0.000 0.093 9.036
ENSG00000124459 E010 1.4698998 0.0101266937 0.929005291 0.97901132 19 43924238 43924310 73 - 0.399 0.386 -0.078
ENSG00000124459 E011 0.0000000       19 43924311 43924312 2 -      
ENSG00000124459 E012 2.6836058 0.0057776463 0.584653534 0.81539604 19 43924402 43924561 160 - 0.604 0.529 -0.341
ENSG00000124459 E013 1.3410955 0.0102596211 0.701228538 0.87831588 19 43925325 43925344 20 - 0.399 0.341 -0.341
ENSG00000124459 E014 2.5916953 0.0056267385 0.327931023 0.62044781 19 43925345 43925458 114 - 0.479 0.612 0.623
ENSG00000124459 E015 0.9978654 0.0119542379 0.171379092 0.44389185 19 43929918 43929956 39 - 0.177 0.386 1.507
ENSG00000124459 E016 0.8621700 0.0132511864 0.757753956 0.90485546 19 43929957 43930000 44 - 0.244 0.291 0.337
ENSG00000124459 E017 1.3801843 0.0255488581 0.039260675 0.19193761 19 43931247 43931341 95 - 0.177 0.498 2.092
ENSG00000124459 E018 1.0060750 0.0267780771 0.033086778 0.17279968 19 43931342 43931365 24 - 0.097 0.426 2.730
ENSG00000124459 E019 0.2435110 0.0164529536 0.967179508   19 43932403 43932603 201 - 0.097 0.093 -0.078
ENSG00000124459 E020 1.4866137 0.0093297585 0.283260793 0.57691883 19 43932604 43932690 87 - 0.302 0.463 0.922
ENSG00000124459 E021 3.3968586 0.0796392477 0.170639616 0.44294236 19 43934426 43934694 269 - 0.743 0.529 -0.927
ENSG00000124459 E022 2.2817106 0.0073077332 0.006918764 0.06259967 19 43934924 43935229 306 - 0.679 0.291 -1.985
ENSG00000124459 E023 0.3634051 0.0169918908 0.552548895   19 43935230 43935282 53 - 0.177 0.093 -1.078

Help

Please Click HERE to learn more details about the results from DEXseq.