ENSG00000124486

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000378308 ENSG00000124486 No_inf pgKDN_inf USP9X protein_coding protein_coding 25.70401 21.94278 27.6029 0.5006826 4.781596 0.3309386 2.625412 0.9612643 3.306621 0.5592118 1.2704600 1.7717783 0.09813333 0.043750 0.121850 0.078100 7.509509e-01 1.542127e-06 FALSE TRUE
ENST00000485180 ENSG00000124486 No_inf pgKDN_inf USP9X protein_coding retained_intron 25.70401 21.94278 27.6029 0.5006826 4.781596 0.3309386 7.605243 6.4146338 7.596183 0.4519777 4.5659758 0.2435584 0.27739167 0.291750 0.224050 -0.067700 8.251315e-01 1.542127e-06 FALSE TRUE
ENST00000703987 ENSG00000124486 No_inf pgKDN_inf USP9X protein_coding protein_coding 25.70401 21.94278 27.6029 0.5006826 4.781596 0.3309386 1.430291 1.1549292 1.759189 0.4872836 0.6987756 0.6028462 0.05809167 0.052125 0.070700 0.018575 9.647050e-01 1.542127e-06 FALSE TRUE
ENST00000704655 ENSG00000124486 No_inf pgKDN_inf USP9X protein_coding nonsense_mediated_decay 25.70401 21.94278 27.6029 0.5006826 4.781596 0.3309386 5.789309 4.6939487 7.710748 0.7597628 0.9245913 0.7148684 0.23637500 0.215925 0.311450 0.095525 8.155338e-01 1.542127e-06 FALSE TRUE
ENST00000704656 ENSG00000124486 No_inf pgKDN_inf USP9X protein_coding nonsense_mediated_decay 25.70401 21.94278 27.6029 0.5006826 4.781596 0.3309386 1.543541 3.5502277 0.000000 0.6713017 0.0000000 -8.4758257 0.06690000 0.161475 0.000000 -0.161475 1.542127e-06 1.542127e-06 FALSE TRUE
MSTRG.29885.10 ENSG00000124486 No_inf pgKDN_inf USP9X protein_coding   25.70401 21.94278 27.6029 0.5006826 4.781596 0.3309386 3.266631 3.1167935 3.305507 1.3174634 0.5155439 0.0845454 0.13145833 0.142950 0.129125 -0.013825 9.730107e-01 1.542127e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000124486 E001 0.3533378 0.0157475328 1.577721e-01   X 41085445 41085465 21 + 0.217 0.000 -11.004
ENSG00000124486 E002 3.6224358 0.0042245465 1.188356e-01 3.643309e-01 X 41085466 41085847 382 + 0.743 0.544 -0.861
ENSG00000124486 E003 2.6318203 0.0406333215 2.000419e-02 1.269600e-01 X 41085848 41085923 76 + 0.689 0.324 -1.809
ENSG00000124486 E004 2.1407680 0.0070905951 2.589829e-03 3.090945e-02 X 41085924 41085939 16 + 0.649 0.192 -2.639
ENSG00000124486 E005 5.0958261 0.0029279400 2.773290e-01 5.706831e-01 X 41085940 41086109 170 + 0.834 0.713 -0.487
ENSG00000124486 E006 0.0000000       X 41094222 41094319 98 +      
ENSG00000124486 E007 6.1897574 0.0023793552 3.295380e-01 6.219443e-01 X 41123471 41123724 254 + 0.898 0.797 -0.391
ENSG00000124486 E008 4.7751803 0.0029266345 9.698348e-05 2.313449e-03 X 41129000 41129145 146 + 0.921 0.426 -2.141
ENSG00000124486 E009 4.4381784 0.0032814674 4.725342e-03 4.760739e-02 X 41131457 41131536 80 + 0.861 0.508 -1.497
ENSG00000124486 E010 4.2553509 0.0547806168 7.194405e-01 8.868439e-01 X 41134725 41134837 113 + 0.743 0.689 -0.224
ENSG00000124486 E011 8.0929771 0.0017856789 3.503843e-02 1.791423e-01 X 41136804 41137022 219 + 1.039 0.834 -0.770
ENSG00000124486 E012 4.8875019 0.0039068837 9.065756e-01 9.702244e-01 X 41140656 41140771 116 + 0.760 0.778 0.072
ENSG00000124486 E013 7.7438426 0.0017907497 1.181648e-01 3.630981e-01 X 41140966 41141217 252 + 1.003 0.851 -0.572
ENSG00000124486 E014 3.7788684 0.0040653171 9.031319e-01 9.688647e-01 X 41141293 41141431 139 + 0.669 0.689 0.081
ENSG00000124486 E015 5.4527475 0.0025981306 2.512866e-01 5.425715e-01 X 41143291 41143443 153 + 0.861 0.735 -0.497
ENSG00000124486 E016 4.7909932 0.0248739660 1.074976e-02 8.423325e-02 X 41144522 41144590 69 + 0.886 0.544 -1.423
ENSG00000124486 E017 4.2055101 0.0346249456 4.917444e-02 2.186458e-01 X 41144591 41144626 36 + 0.820 0.544 -1.169
ENSG00000124486 E018 9.0565405 0.0237996540 4.654440e-02 2.117359e-01 X 41148369 41148575 207 + 1.087 0.868 -0.815
ENSG00000124486 E019 2.0525530 0.0106974054 2.234750e-01 5.111090e-01 X 41150921 41150951 31 + 0.555 0.378 -0.902
ENSG00000124486 E020 3.9732238 0.0034462164 4.907049e-02 2.184254e-01 X 41150952 41151057 106 + 0.791 0.544 -1.054
ENSG00000124486 E021 0.3628435 0.0166363021 7.418811e-01   X 41152933 41152947 15 + 0.156 0.106 -0.639
ENSG00000124486 E022 5.4461551 0.0093409218 1.617642e-01 4.300440e-01 X 41152948 41153081 134 + 0.874 0.713 -0.639
ENSG00000124486 E023 5.0784897 0.0027080167 1.607467e-01 4.287087e-01 X 41162790 41162877 88 + 0.848 0.689 -0.639
ENSG00000124486 E024 19.5681555 0.0018822135 2.423052e-03 2.942028e-02 X 41165872 41166214 343 + 1.394 1.188 -0.720
ENSG00000124486 E025 0.0000000       X 41167145 41167481 337 +      
ENSG00000124486 E026 7.0281615 0.0023449706 2.302148e-01 5.187746e-01 X 41167482 41167577 96 + 0.954 0.834 -0.456
ENSG00000124486 E027 11.1363533 0.0012273507 3.060229e-01 5.992589e-01 X 41168007 41168218 212 + 1.039 1.130 0.330
ENSG00000124486 E028 0.0000000       X 41168219 41168242 24 +      
ENSG00000124486 E029 15.5364120 0.0009414043 1.351656e-01 3.908440e-01 X 41169995 41170235 241 + 1.262 1.156 -0.376
ENSG00000124486 E030 12.1905207 0.0041343489 8.245276e-03 7.053144e-02 X 41170470 41170619 150 + 1.207 0.982 -0.814
ENSG00000124486 E031 4.6867400 0.0188695622 2.863819e-02 1.584727e-01 X 41171838 41171856 19 + 0.861 0.577 -1.175
ENSG00000124486 E032 10.5383061 0.0021920676 1.167442e-01 3.604788e-01 X 41171857 41171958 102 + 1.117 0.982 -0.492
ENSG00000124486 E033 0.0000000       X 41183994 41183997 4 +      
ENSG00000124486 E034 9.6491971 0.0271440979 7.145733e-01 8.849551e-01 X 41183998 41184128 131 + 1.003 1.052 0.178
ENSG00000124486 E035 15.1838040 0.0009506396 2.031917e-01 4.857085e-01 X 41184397 41184675 279 + 1.246 1.156 -0.321
ENSG00000124486 E036 0.0000000       X 41184676 41184740 65 +      
ENSG00000124486 E037 9.2671590 0.0015611733 9.112402e-01 9.717870e-01 X 41186517 41186642 126 + 1.012 1.007 -0.021
ENSG00000124486 E038 7.5682640 0.0039048760 8.635513e-01 9.527896e-01 X 41187992 41188065 74 + 0.921 0.943 0.081
ENSG00000124486 E039 8.5977946 0.0703557594 3.943066e-01 6.791093e-01 X 41188066 41188117 52 + 1.039 0.900 -0.518
ENSG00000124486 E040 14.6489395 0.0020054277 4.050454e-02 1.951905e-01 X 41189309 41189475 167 + 1.257 1.102 -0.550
ENSG00000124486 E041 0.1271363 0.0123302493 4.226923e-01   X 41189476 41189922 447 + 0.000 0.106 11.621
ENSG00000124486 E042 0.1187032 0.0118420495 6.814057e-01   X 41195905 41196005 101 + 0.085 0.000 -12.161
ENSG00000124486 E043 13.8104182 0.0045255882 6.395491e-02 2.547157e-01 X 41196251 41196359 109 + 1.230 1.083 -0.526
ENSG00000124486 E044 16.1554971 0.0008544304 2.495403e-01 5.404886e-01 X 41196592 41196738 147 + 1.267 1.188 -0.278
ENSG00000124486 E045 0.4998298 0.0276378353 2.209513e-01   X 41197265 41197363 99 + 0.085 0.263 1.946
ENSG00000124486 E046 16.0249595 0.0039313895 2.290014e-01 5.177075e-01 X 41197364 41197510 147 + 1.267 1.180 -0.306
ENSG00000124486 E047 17.7953982 0.0008215257 2.160313e-02 1.331592e-01 X 41198528 41198750 223 + 1.337 1.180 -0.551
ENSG00000124486 E048 28.3948997 0.0080727031 1.435950e-01 4.035355e-01 X 41201060 41201280 221 + 1.506 1.414 -0.317
ENSG00000124486 E049 0.2438580 0.0163723245 8.528258e-01   X 41205059 41205302 244 + 0.085 0.106 0.361
ENSG00000124486 E050 31.1554679 0.0004445365 4.645315e-01 7.339907e-01 X 41205303 41205493 191 + 1.521 1.487 -0.116
ENSG00000124486 E051 11.8464827 0.0250555652 8.656724e-01 9.537297e-01 X 41210509 41210555 47 + 1.095 1.121 0.092
ENSG00000124486 E052 19.2309870 0.0269707819 5.498713e-01 7.945548e-01 X 41210556 41210682 127 + 1.324 1.279 -0.156
ENSG00000124486 E053 18.5767756 0.0007601855 1.710208e-01 4.434041e-01 X 41214568 41214709 142 + 1.328 1.240 -0.311
ENSG00000124486 E054 100.0503768 0.0014940318 5.254789e-01 7.782127e-01 X 41215899 41216652 754 + 2.010 1.994 -0.053
ENSG00000124486 E055 23.1758098 0.0006225691 8.524343e-01 9.478444e-01 X 41217220 41217343 124 + 1.374 1.391 0.056
ENSG00000124486 E056 41.6728233 0.0004869804 3.412580e-01 6.328591e-01 X 41218372 41218597 226 + 1.605 1.654 0.166
ENSG00000124486 E057 27.4156076 0.0005178118 1.676356e-01 4.383214e-01 X 41219102 41219231 130 + 1.412 1.495 0.284
ENSG00000124486 E058 31.1972721 0.0004391626 8.212524e-01 9.350721e-01 X 41223217 41223327 111 + 1.509 1.502 -0.024
ENSG00000124486 E059 26.7552015 0.0005036708 4.553341e-01 7.278625e-01 X 41223328 41223402 75 + 1.419 1.467 0.163
ENSG00000124486 E060 52.4794461 0.0090775781 5.576010e-01 7.994520e-01 X 41224742 41224962 221 + 1.739 1.712 -0.091
ENSG00000124486 E061 37.1860321 0.0073490593 7.533219e-01 9.028988e-01 X 41225049 41225137 89 + 1.586 1.572 -0.049
ENSG00000124486 E062 0.2435110 0.0164005947 8.529268e-01   X 41228983 41229252 270 + 0.085 0.106 0.361
ENSG00000124486 E063 53.7131037 0.0012356002 5.683138e-01 8.058534e-01 X 41229253 41229409 157 + 1.723 1.752 0.098
ENSG00000124486 E064 70.9857360 0.0003550079 1.046020e-02 8.269610e-02 X 41229567 41229779 213 + 1.810 1.905 0.321
ENSG00000124486 E065 1.8501214 0.0074622812 2.212794e-01 5.083911e-01 X 41229780 41229827 48 + 0.361 0.544 0.946
ENSG00000124486 E066 0.0000000       X 41229828 41229896 69 +      
ENSG00000124486 E067 46.9376767 0.0003884089 6.860746e-05 1.725874e-03 X 41230501 41230596 96 + 1.589 1.767 0.603
ENSG00000124486 E068 234.4857877 0.0015465963 4.398025e-12 5.294712e-10 X 41232387 41236579 4193 + 2.290 2.450 0.532

Help

Please Click HERE to learn more details about the results from DEXseq.