ENSG00000124608

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000244571 ENSG00000124608 No_inf pgKDN_inf AARS2 protein_coding protein_coding 12.87015 10.43565 13.44783 0.4609301 0.6563412 0.3655435 8.627195 6.9451288 8.135250 0.1858464 1.1155456 0.2278818 0.6743333 0.670675 0.617950 -0.052725 0.94399568 0.02737684 FALSE  
ENST00000491573 ENSG00000124608 No_inf pgKDN_inf AARS2 protein_coding protein_coding_CDS_not_defined 12.87015 10.43565 13.44783 0.4609301 0.6563412 0.3655435 0.429477 0.8750939 0.000000 0.2581940 0.0000000 -6.4677586 0.0363500 0.081475 0.000000 -0.081475 0.02737684 0.02737684    
MSTRG.24752.2 ENSG00000124608 No_inf pgKDN_inf AARS2 protein_coding   12.87015 10.43565 13.44783 0.4609301 0.6563412 0.3655435 1.686845 1.2397266 3.539679 0.7446978 1.2007955 1.5060762 0.1308833 0.115500 0.258500 0.143000 0.77437943 0.02737684 FALSE  
MSTRG.24752.3 ENSG00000124608 No_inf pgKDN_inf AARS2 protein_coding   12.87015 10.43565 13.44783 0.4609301 0.6563412 0.3655435 2.126628 1.3757015 1.772901 0.4361914 0.9635556 0.3636099 0.1584333 0.132375 0.123525 -0.008850 0.93509929 0.02737684 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000124608 E001 1.4892906 0.0560302720 0.151516593 0.4149013 6 44298731 44298822 92 - 0.273 0.504 1.322
ENSG00000124608 E002 60.8459687 0.0115891008 0.915911298 0.9736624 6 44298823 44300215 1393 - 1.793 1.787 -0.020
ENSG00000124608 E003 44.9607576 0.0004574784 0.186104806 0.4639953 6 44300216 44300571 356 - 1.636 1.689 0.182
ENSG00000124608 E004 18.6210118 0.0238243380 0.780159329 0.9152571 6 44300572 44300711 140 - 1.306 1.274 -0.113
ENSG00000124608 E005 1.2593127 0.0099597787 0.002551299 0.0305578 6 44300712 44301155 444 - 0.086 0.540 3.493
ENSG00000124608 E006 15.2312814 0.0363844601 0.900720748 0.9678771 6 44301156 44301266 111 - 1.219 1.198 -0.072
ENSG00000124608 E007 14.4919803 0.0099756164 0.895466490 0.9655320 6 44301381 44301464 84 - 1.195 1.183 -0.043
ENSG00000124608 E008 17.8782809 0.0032412258 0.396754659 0.6813315 6 44302060 44302170 111 - 1.302 1.241 -0.213
ENSG00000124608 E009 13.8210598 0.0010432398 0.455979435 0.7283958 6 44302391 44302513 123 - 1.143 1.198 0.195
ENSG00000124608 E010 8.7985467 0.0251336674 0.676041745 0.8658253 6 44302802 44302910 109 - 0.969 1.013 0.163
ENSG00000124608 E011 9.0055236 0.0032328854 0.680214252 0.8679744 6 44303066 44303175 110 - 1.017 0.977 -0.149
ENSG00000124608 E012 10.8681010 0.0013283303 0.584317723 0.8152153 6 44303286 44303423 138 - 1.053 1.097 0.161
ENSG00000124608 E013 12.2868090 0.0020083716 0.451484606 0.7245503 6 44304181 44304321 141 - 1.150 1.087 -0.226
ENSG00000124608 E014 8.8800830 0.0141922133 0.468306571 0.7365248 6 44304420 44304533 114 - 1.027 0.951 -0.279
ENSG00000124608 E015 9.4059058 0.0015055372 0.666335791 0.8613391 6 44304645 44304817 173 - 0.999 1.036 0.135
ENSG00000124608 E016 12.2368265 0.0011888264 0.346234947 0.6370827 6 44305054 44305198 145 - 1.085 1.159 0.265
ENSG00000124608 E017 9.6034848 0.0700040832 0.460766534 0.7319790 6 44305653 44305786 134 - 1.061 0.977 -0.309
ENSG00000124608 E018 7.7625638 0.0020298402 0.174647612 0.4484947 6 44306280 44306391 112 - 0.999 0.863 -0.511
ENSG00000124608 E019 2.5395471 0.0057236784 0.309753015 0.6030473 6 44306494 44306532 39 - 0.609 0.465 -0.677
ENSG00000124608 E020 0.2457744 0.0162563842 0.859376331   6 44306923 44307031 109 - 0.086 0.105 0.323
ENSG00000124608 E021 0.0000000       6 44307249 44307394 146 -      
ENSG00000124608 E022 6.1307628 0.0027394647 0.278636376 0.5718625 6 44310299 44310443 145 - 0.796 0.909 0.438
ENSG00000124608 E023 10.7295049 0.0015280538 0.999879256 1.0000000 6 44310994 44311161 168 - 1.069 1.067 -0.006
ENSG00000124608 E024 12.0694272 0.0014174296 0.979023405 0.9973490 6 44311390 44311535 146 - 1.115 1.115 0.001
ENSG00000124608 E025 8.9843639 0.0016652543 0.258950365 0.5514799 6 44312072 44312263 192 - 1.044 0.938 -0.393
ENSG00000124608 E026 8.1548326 0.0017315971 0.676598072 0.8659598 6 44313081 44313347 267 - 0.979 0.938 -0.155

Help

Please Click HERE to learn more details about the results from DEXseq.