ENSG00000124733

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000643776 ENSG00000124733 No_inf pgKDN_inf MEA1 protein_coding protein_coding 74.03337 76.29962 74.34429 0.9029572 1.678571 -0.03744902 65.296087 62.304218 68.5546012 0.5632000 0.8117166 0.1379025 0.88320000 0.816825 0.922850 0.106025 1.095212e-03 6.130097e-07 FALSE TRUE
ENST00000645410 ENSG00000124733 No_inf pgKDN_inf MEA1 protein_coding protein_coding 74.03337 76.29962 74.34429 0.9029572 1.678571 -0.03744902 4.208696 9.972817 0.9901669 0.3654522 0.2374771 -3.3192062 0.05568333 0.130650 0.013175 -0.117475 6.130097e-07 6.130097e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000124733 E001 0.0000000       6 43011143 43012081 939 -      
ENSG00000124733 E002 0.0000000       6 43012082 43012093 12 -      
ENSG00000124733 E003 115.2949579 0.0001527218 5.264051e-01 7.787346e-01 6 43012094 43012570 477 - 2.053 2.070 0.058
ENSG00000124733 E004 63.1675615 0.0002695094 3.009883e-02 1.632152e-01 6 43012571 43012621 51 - 1.844 1.770 -0.248
ENSG00000124733 E005 82.5464752 0.0002157015 2.771643e-01 5.705564e-01 6 43012926 43013028 103 - 1.936 1.906 -0.101
ENSG00000124733 E006 97.0570826 0.0001877721 3.137113e-01 6.068326e-01 6 43013115 43013389 275 - 2.002 1.977 -0.083
ENSG00000124733 E007 1.3693941 0.0106612395 2.088354e-01 4.929030e-01 6 43013390 43013591 202 - 0.254 0.449 1.189
ENSG00000124733 E008 0.2447669 0.0162758827 9.003853e-01   6 43013592 43013684 93 - 0.102 0.089 -0.226
ENSG00000124733 E009 2.0690145 0.0066736169 2.932125e-01 5.867653e-01 6 43013786 43013897 112 - 0.562 0.412 -0.740
ENSG00000124733 E010 7.2681475 0.0076549935 5.951722e-01 8.220207e-01 6 43013898 43013983 86 - 0.882 0.939 0.218
ENSG00000124733 E011 0.0000000       6 43014062 43014279 218 -      
ENSG00000124733 E012 12.7064459 0.0011053468 7.997273e-13 1.065000e-10 6 43016420 43016794 375 - 0.647 1.321 2.533
ENSG00000124733 E013 2.2499332 0.0063028180 3.814978e-02 1.885383e-01 6 43016795 43016868 74 - 0.314 0.620 1.582

Help

Please Click HERE to learn more details about the results from DEXseq.