ENSG00000125149

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000569277 ENSG00000125149 No_inf pgKDN_inf PHAF1 protein_coding protein_coding 17.0247 10.85675 22.07189 0.7293224 2.365292 1.022943 4.184276 3.585205 3.041845 0.8941897 1.2352598 -0.2363926 0.2667583 0.317450 0.159600 -0.157850 0.62788090 0.01804813 FALSE FALSE
MSTRG.11318.2 ENSG00000125149 No_inf pgKDN_inf PHAF1 protein_coding   17.0247 10.85675 22.07189 0.7293224 2.365292 1.022943 8.217348 5.285527 8.803303 0.5594330 0.6877968 0.7349084 0.4981000 0.502725 0.407975 -0.094750 0.83097553 0.01804813 FALSE TRUE
MSTRG.11318.7 ENSG00000125149 No_inf pgKDN_inf PHAF1 protein_coding   17.0247 10.85675 22.07189 0.7293224 2.365292 1.022943 2.940718 0.000000 8.822155 0.0000000 3.6796093 9.7866217 0.1191750 0.000000 0.357525 0.357525 0.01804813 0.01804813   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000125149 E001 0.3703650 0.0166038822 0.443443821   16 67109941 67109945 5 + 0.085 0.192 1.361
ENSG00000125149 E002 0.4890031 0.0158216784 0.808239844   16 67109946 67109946 1 + 0.156 0.192 0.361
ENSG00000125149 E003 0.8501474 0.0173220110 0.958075906 0.98998140 16 67109947 67109957 11 + 0.270 0.263 -0.054
ENSG00000125149 E004 0.9772837 0.0352889361 0.731459936 0.89325394 16 67109958 67109961 4 + 0.270 0.324 0.361
ENSG00000125149 E005 0.9772837 0.0352889361 0.731459936 0.89325394 16 67109962 67109962 1 + 0.270 0.324 0.361
ENSG00000125149 E006 1.2146250 0.0110590036 0.805399276 0.92792020 16 67109963 67109976 14 + 0.361 0.324 -0.224
ENSG00000125149 E007 1.2054016 0.0108341182 0.370999104 0.65908243 16 67109977 67109989 13 + 0.400 0.263 -0.861
ENSG00000125149 E008 0.5980397 0.0156388765 0.270557337 0.56423476 16 67109990 67110004 15 + 0.270 0.106 -1.639
ENSG00000125149 E009 0.1268540 0.0123262285 0.420794825   16 67110005 67110116 112 + 0.000 0.106 12.132
ENSG00000125149 E010 0.1268540 0.0123262285 0.420794825   16 67110117 67110118 2 + 0.000 0.106 12.132
ENSG00000125149 E011 1.4515204 0.0092040684 0.457204914 0.72923630 16 67110119 67110144 26 + 0.436 0.324 -0.639
ENSG00000125149 E012 0.9523849 0.0116955588 0.056978487 0.23853743 16 67110145 67110146 2 + 0.400 0.106 -2.446
ENSG00000125149 E013 2.7875450 0.1030741135 0.447529788 0.72165132 16 67110147 67110239 93 + 0.627 0.508 -0.546
ENSG00000125149 E014 0.0000000       16 67120095 67120111 17 +      
ENSG00000125149 E015 3.0164297 0.0054699015 0.102919632 0.33537958 16 67120112 67120194 83 + 0.689 0.469 -1.002
ENSG00000125149 E016 0.4703418 0.0158695999 0.077604516   16 67121605 67121630 26 + 0.270 0.000 -14.124
ENSG00000125149 E017 4.1311763 0.0138287676 0.514907159 0.77126677 16 67125959 67126042 84 + 0.743 0.663 -0.331
ENSG00000125149 E018 5.1365259 0.0029678943 0.632348557 0.84251697 16 67131286 67131329 44 + 0.760 0.816 0.224
ENSG00000125149 E019 0.1265070 0.0123361977 0.420702844   16 67131989 67132445 457 + 0.000 0.106 12.132
ENSG00000125149 E020 5.2379186 0.0191348429 0.787720701 0.91863277 16 67132446 67132525 80 + 0.806 0.778 -0.113
ENSG00000125149 E021 0.5085453 0.7505532866 0.257882207 0.55006825 16 67132526 67132816 291 + 0.000 0.324 13.287
ENSG00000125149 E022 3.8754454 0.0038058293 0.271714177 0.56546000 16 67132817 67132911 95 + 0.743 0.608 -0.572
ENSG00000125149 E023 0.0000000       16 67132912 67132934 23 +      
ENSG00000125149 E024 5.3723190 0.0027650506 0.838629038 0.94210680 16 67134168 67134265 98 + 0.791 0.816 0.098
ENSG00000125149 E025 0.2533610 0.0160718277 0.169922980   16 67134266 67134354 89 + 0.000 0.192 13.029
ENSG00000125149 E026 8.9846184 0.0015553718 0.281575951 0.57494198 16 67134355 67134467 113 + 1.039 0.943 -0.355
ENSG00000125149 E027 0.0000000       16 67134468 67134627 160 +      
ENSG00000125149 E028 0.4889692 0.4968195840 0.875641394   16 67134628 67134771 144 + 0.156 0.192 0.362
ENSG00000125149 E029 0.4979743 0.0218503194 0.217069394   16 67134772 67134810 39 + 0.085 0.263 1.946
ENSG00000125149 E030 0.6089350 0.2489509402 0.879180300 0.95915428 16 67134811 67135192 382 + 0.217 0.192 -0.224
ENSG00000125149 E031 2.2475808 0.0064037337 0.003617744 0.03964585 16 67135193 67136255 1063 + 0.270 0.689 2.168
ENSG00000125149 E032 0.1186381 0.0118651282 0.683586829   16 67136256 67136310 55 + 0.085 0.000 -12.425
ENSG00000125149 E033 0.4989795 0.0172057064 0.215999963   16 67139634 67139983 350 + 0.085 0.263 1.946
ENSG00000125149 E034 9.2986315 0.0017633229 0.398519826 0.68236351 16 67139984 67140117 134 + 0.974 1.052 0.285
ENSG00000125149 E035 7.7465385 0.0019593253 0.061681372 0.24956663 16 67140511 67140594 84 + 0.848 1.030 0.683
ENSG00000125149 E036 7.9622566 0.0017286937 0.263166937 0.55609017 16 67144294 67144376 83 + 0.898 1.007 0.405
ENSG00000125149 E037 5.8697219 0.0130851570 0.613171964 0.83181039 16 67144834 67144877 44 + 0.806 0.868 0.241
ENSG00000125149 E038 6.8508841 0.0021934242 0.517314182 0.77285458 16 67145376 67145419 44 + 0.861 0.929 0.258
ENSG00000125149 E039 6.5838601 0.0021036301 0.940330653 0.98303567 16 67145570 67145628 59 + 0.874 0.884 0.039
ENSG00000125149 E040 3.1530047 0.0049234139 0.573123524 0.80875510 16 67146278 67146283 6 + 0.649 0.577 -0.317
ENSG00000125149 E041 6.5670226 0.0550208237 0.924130227 0.97695120 16 67146284 67146350 67 + 0.886 0.868 -0.068
ENSG00000125149 E042 6.5711456 0.0174754064 0.860170281 0.95153011 16 67147045 67147094 50 + 0.886 0.868 -0.069
ENSG00000125149 E043 13.8075211 0.0010522330 0.048252381 0.21622159 16 67147095 67147305 211 + 1.230 1.083 -0.526
ENSG00000125149 E044 45.6103527 0.0004526465 0.932714933 0.98053107 16 67147306 67148544 1239 + 1.664 1.670 0.020

Help

Please Click HERE to learn more details about the results from DEXseq.