ENSG00000125354

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000343984 ENSG00000125354 No_inf pgKDN_inf SEPTIN6 protein_coding protein_coding 12.97401 14.2713 11.95911 1.187767 0.6797482 -0.2548114 0.9808588 2.4156484 0.24111127 0.5084320 0.24111127 -3.27197181 0.06880000 0.164400 0.023450 -0.140950 0.08310375 0.00748441 FALSE TRUE
ENST00000360156 ENSG00000125354 No_inf pgKDN_inf SEPTIN6 protein_coding protein_coding 12.97401 14.2713 11.95911 1.187767 0.6797482 -0.2548114 0.4106752 0.9309385 0.08665294 0.2577500 0.05036947 -3.28321490 0.03185000 0.070150 0.007625 -0.062525 0.25698886 0.00748441 FALSE TRUE
ENST00000394610 ENSG00000125354 No_inf pgKDN_inf SEPTIN6 protein_coding protein_coding 12.97401 14.2713 11.95911 1.187767 0.6797482 -0.2548114 2.0913546 2.2451620 2.19940440 0.2466887 0.21277713 -0.02957358 0.16625833 0.163475 0.185575 0.022100 0.91169601 0.00748441 FALSE TRUE
ENST00000467310 ENSG00000125354 No_inf pgKDN_inf SEPTIN6 protein_coding protein_coding_CDS_not_defined 12.97401 14.2713 11.95911 1.187767 0.6797482 -0.2548114 4.5453958 5.7569505 3.21594099 1.3087308 0.81144766 -0.83808859 0.33911667 0.389200 0.264025 -0.125175 0.73773753 0.00748441 FALSE TRUE
ENST00000481072 ENSG00000125354 No_inf pgKDN_inf SEPTIN6 protein_coding protein_coding_CDS_not_defined 12.97401 14.2713 11.95911 1.187767 0.6797482 -0.2548114 0.8801942 1.6340415 0.24920351 0.3906139 0.24920351 -2.66508961 0.06821667 0.123900 0.021800 -0.102100 0.23506882 0.00748441 FALSE FALSE
ENST00000489216 ENSG00000125354 No_inf pgKDN_inf SEPTIN6 protein_coding protein_coding 12.97401 14.2713 11.95911 1.187767 0.6797482 -0.2548114 3.3709804 0.7656204 5.96679894 0.4432112 0.68361583 2.94595041 0.27950833 0.054500 0.497525 0.443025 0.00748441 0.00748441 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000125354 E001 2.6500440 0.0265604456 0.0010301810 0.015327387 X 119615724 119616711 988 - 0.191 0.709 2.893
ENSG00000125354 E002 0.1268540 0.0124235673 0.6953236533   X 119616712 119616715 4 - 0.000 0.085 10.803
ENSG00000125354 E003 0.2541163 0.0164829522 0.3441236019   X 119616716 119616742 27 - 0.000 0.156 11.722
ENSG00000125354 E004 7.1219881 0.0043532638 0.6483650401 0.851565411 X 119616945 119617638 694 - 0.928 0.887 -0.156
ENSG00000125354 E005 23.9463970 0.0006868455 0.0005556475 0.009488143 X 119617639 119618712 1074 - 1.259 1.468 0.724
ENSG00000125354 E006 2.9839318 0.0047218013 0.1491219383 0.411393484 X 119618713 119618786 74 - 0.468 0.670 0.925
ENSG00000125354 E007 2.9638818 0.0049741134 0.5513800570 0.795264802 X 119618787 119619308 522 - 0.543 0.628 0.382
ENSG00000125354 E008 28.6722549 0.0015893522 0.0482871154 0.216269497 X 119619309 119620051 743 - 1.399 1.510 0.382
ENSG00000125354 E009 4.8780047 0.0029040522 0.1452312165 0.405527566 X 119625335 119625379 45 - 0.851 0.690 -0.645
ENSG00000125354 E010 0.3812526 0.0165476754 0.1630405666   X 119625380 119625396 17 - 0.000 0.217 12.248
ENSG00000125354 E011 2.5208580 0.0506635730 0.0024619635 0.029758750 X 119628816 119629317 502 - 0.191 0.690 2.815
ENSG00000125354 E012 16.0971238 0.0010577533 0.7178591686 0.886507264 X 119629318 119629508 191 - 1.239 1.220 -0.068
ENSG00000125354 E013 13.4508616 0.0011157628 0.0726051226 0.273532040 X 119633360 119633492 133 - 1.225 1.096 -0.460
ENSG00000125354 E014 0.1170040 0.0116350192 0.4132324817   X 119633493 119633502 10 - 0.106 0.000 -11.922
ENSG00000125354 E015 12.9325383 0.0011759803 0.0177096163 0.117081447 X 119637027 119637195 169 - 1.232 1.056 -0.628
ENSG00000125354 E016 6.8309802 0.0024165204 0.0748231789 0.279061844 X 119640692 119640788 97 - 0.981 0.807 -0.666
ENSG00000125354 E017 8.2128792 0.0020248230 0.4831490656 0.747877117 X 119649937 119650098 162 - 0.994 0.933 -0.226
ENSG00000125354 E018 11.3266167 0.0024830747 0.9907999919 1.000000000 X 119652854 119653040 187 - 1.082 1.088 0.023
ENSG00000125354 E019 9.9175936 0.0016766571 0.1929214694 0.472726484 X 119663482 119663677 196 - 1.092 0.985 -0.391
ENSG00000125354 E020 6.4540209 0.0024891675 0.0550302731 0.233701004 X 119675554 119675668 115 - 0.969 0.777 -0.739
ENSG00000125354 E021 3.7608985 0.0042268026 0.0479580565 0.215484254 X 119693076 119693370 295 - 0.797 0.556 -1.018

Help

Please Click HERE to learn more details about the results from DEXseq.