ENSG00000125450

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000245544 ENSG00000125450 No_inf pgKDN_inf NUP85 protein_coding protein_coding 40.55272 42.29875 34.92473 3.344375 1.189625 -0.276294 12.726307 9.974956 16.9213899 0.5774532 1.3314374 0.7618725 0.33735833 0.243825 0.486325 0.242500 0.03046363 0.02091583 FALSE TRUE
ENST00000540768 ENSG00000125450 No_inf pgKDN_inf NUP85 protein_coding protein_coding 40.55272 42.29875 34.92473 3.344375 1.189625 -0.276294 2.488113 2.881385 2.1834490 0.2407114 0.2398394 -0.3985596 0.06299167 0.070075 0.063400 -0.006675 0.96224854 0.02091583 FALSE TRUE
ENST00000578294 ENSG00000125450 No_inf pgKDN_inf NUP85 protein_coding retained_intron 40.55272 42.29875 34.92473 3.344375 1.189625 -0.276294 4.060170 7.379764 3.1295555 2.0954705 0.6328402 -1.2349681 0.09940000 0.169475 0.088500 -0.080975 0.57782949 0.02091583   FALSE
ENST00000583070 ENSG00000125450 No_inf pgKDN_inf NUP85 protein_coding protein_coding 40.55272 42.29875 34.92473 3.344375 1.189625 -0.276294 3.434718 5.597657 0.0000000 2.3456903 0.0000000 -9.1312544 0.07583333 0.122425 0.000000 -0.122425 0.02091583 0.02091583 FALSE FALSE
ENST00000583569 ENSG00000125450 No_inf pgKDN_inf NUP85 protein_coding protein_coding 40.55272 42.29875 34.92473 3.344375 1.189625 -0.276294 2.354502 2.094074 0.8058829 2.0940738 0.8058829 -1.3667513 0.05515000 0.043200 0.023600 -0.019600 1.00000000 0.02091583 FALSE FALSE
MSTRG.13274.1 ENSG00000125450 No_inf pgKDN_inf NUP85 protein_coding   40.55272 42.29875 34.92473 3.344375 1.189625 -0.276294 2.657615 4.101989 2.2250296 0.7767449 0.8511420 -0.8795426 0.06914167 0.097275 0.066100 -0.031175 0.80006412 0.02091583 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000125450 E001 0.3726934 0.0165634668 0.61770396   17 75205618 75205658 41 + 0.097 0.169 0.924
ENSG00000125450 E002 0.3726934 0.0165634668 0.61770396   17 75205659 75205678 20 + 0.097 0.169 0.924
ENSG00000125450 E003 0.3726934 0.0165634668 0.61770396   17 75205679 75205689 11 + 0.097 0.169 0.924
ENSG00000125450 E004 1.3711851 0.0121370341 0.15429019 0.41966247 17 75205690 75205706 17 + 0.244 0.464 1.339
ENSG00000125450 E005 1.4813901 0.0282994392 0.64428050 0.84932966 17 75205707 75205708 2 + 0.353 0.426 0.410
ENSG00000125450 E006 1.4813901 0.0282994392 0.64428050 0.84932966 17 75205709 75205712 4 + 0.353 0.426 0.410
ENSG00000125450 E007 2.4536691 0.0166299084 0.90667262 0.97026927 17 75205713 75205719 7 + 0.546 0.529 -0.076
ENSG00000125450 E008 8.7781524 0.0270849130 0.22287732 0.51031714 17 75205720 75205794 75 + 1.053 0.924 -0.479
ENSG00000125450 E009 0.4975013 0.0152787607 0.34587597   17 75208155 75208425 271 + 0.097 0.234 1.509
ENSG00000125450 E010 0.3538994 0.0394338494 0.09617319   17 75208504 75208526 23 + 0.244 0.000 -12.409
ENSG00000125450 E011 6.8146783 0.0775607560 0.24254770 0.53217289 17 75208527 75208536 10 + 0.968 0.812 -0.596
ENSG00000125450 E012 16.1273775 0.0109694388 0.28997793 0.58365421 17 75208537 75208620 84 + 1.275 1.192 -0.295
ENSG00000125450 E013 26.5261533 0.0027906320 0.18046353 0.45592654 17 75209823 75209985 163 + 1.479 1.399 -0.275
ENSG00000125450 E014 14.8685597 0.0010502024 0.47993861 0.74547156 17 75211992 75212062 71 + 1.171 1.224 0.187
ENSG00000125450 E015 9.0062589 0.0017554822 0.12748730 0.37860800 17 75213076 75213119 44 + 0.918 1.060 0.526
ENSG00000125450 E016 6.5097819 0.0198274748 0.64372599 0.84905524 17 75215754 75215800 47 + 0.847 0.898 0.197
ENSG00000125450 E017 5.7460828 0.0598462809 0.69255867 0.87418975 17 75215801 75215823 23 + 0.862 0.796 -0.261
ENSG00000125450 E018 0.1272623 0.0124427601 0.56721297   17 75216290 75216310 21 + 0.000 0.093 10.568
ENSG00000125450 E019 0.2543986 0.0160799323 0.26118383   17 75216311 75216376 66 + 0.000 0.169 11.568
ENSG00000125450 E020 0.2539903 0.0159389213 0.26144603   17 75216386 75216500 115 + 0.000 0.169 11.568
ENSG00000125450 E021 5.2652955 0.0421151693 0.80759227 0.92900222 17 75218185 75218185 1 + 0.815 0.779 -0.143
ENSG00000125450 E022 5.7437209 0.0078225007 0.55200321 0.79567419 17 75218186 75218207 22 + 0.862 0.796 -0.260
ENSG00000125450 E023 12.4319013 0.0011574744 0.09836874 0.32719210 17 75218208 75218292 85 + 1.192 1.060 -0.474
ENSG00000125450 E024 9.2260283 0.0016332577 0.02191638 0.13444475 17 75218293 75218306 14 + 1.108 0.898 -0.772
ENSG00000125450 E025 8.3996358 0.0020310514 0.12504473 0.37491433 17 75225103 75225123 21 + 1.043 0.898 -0.540
ENSG00000125450 E026 15.1116746 0.0010106844 0.08301299 0.29691774 17 75225124 75225237 114 + 1.269 1.142 -0.450
ENSG00000125450 E027 11.2289257 0.0025632205 0.28370933 0.57740968 17 75225342 75225367 26 + 1.132 1.042 -0.327
ENSG00000125450 E028 10.8709299 0.0068465136 0.45803861 0.72995462 17 75225368 75225390 23 + 1.107 1.042 -0.238
ENSG00000125450 E029 19.1490077 0.0058394631 0.15607089 0.42222750 17 75225391 75225464 74 + 1.354 1.254 -0.352
ENSG00000125450 E030 1.0976485 0.0110642401 0.68206384 0.86838278 17 75225465 75225697 233 + 0.353 0.291 -0.397
ENSG00000125450 E031 17.9834273 0.0008410612 0.56739720 0.80523699 17 75225698 75225767 70 + 1.298 1.259 -0.134
ENSG00000125450 E032 9.6876937 0.0035930657 0.91730112 0.97402631 17 75225768 75225797 30 + 1.023 1.032 0.034
ENSG00000125450 E033 10.8074654 0.0012598149 0.69743625 0.87655014 17 75225798 75225829 32 + 1.053 1.087 0.121
ENSG00000125450 E034 0.8709136 0.1674370021 0.33352380 0.62556082 17 75225830 75225920 91 + 0.177 0.341 1.245
ENSG00000125450 E035 0.9978014 0.0117618870 0.17468974 0.44850367 17 75225921 75226022 102 + 0.177 0.386 1.509
ENSG00000125450 E036 1.6255191 0.0084352832 0.06037051 0.24652920 17 75226023 75226050 28 + 0.244 0.529 1.661
ENSG00000125450 E037 8.3718611 0.0015965301 0.32284722 0.61568569 17 75226051 75226055 5 + 0.918 1.013 0.352
ENSG00000125450 E038 13.8957380 0.0009580060 0.34776112 0.63834883 17 75226056 75226107 52 + 1.132 1.205 0.258
ENSG00000125450 E039 12.8658715 0.0011429461 0.86091626 0.95184557 17 75226108 75226157 50 + 1.148 1.135 -0.048
ENSG00000125450 E040 1.2593778 0.3202247369 0.09097855 0.31319570 17 75226745 75226978 234 + 0.097 0.498 3.094
ENSG00000125450 E041 1.6155405 0.0089519229 0.19608618 0.47669703 17 75227948 75228160 213 + 0.302 0.498 1.094
ENSG00000125450 E042 4.5729408 0.0581204223 0.28548826 0.57915910 17 75228161 75228384 224 + 0.655 0.812 0.640
ENSG00000125450 E043 9.1249186 0.0019674305 0.16406169 0.43324046 17 75228385 75228997 613 + 0.931 1.060 0.477
ENSG00000125450 E044 4.4164024 0.0229616795 0.88272755 0.96055661 17 75228998 75229131 134 + 0.722 0.743 0.085
ENSG00000125450 E045 0.7517739 0.0253248527 0.10934011 0.34703405 17 75231138 75231339 202 + 0.097 0.341 2.246
ENSG00000125450 E046 14.8196998 0.0045539239 0.71525911 0.88527596 17 75231340 75231423 84 + 1.213 1.185 -0.099
ENSG00000125450 E047 15.3647814 0.0194038958 0.46505498 0.73434864 17 75231573 75231638 66 + 1.178 1.242 0.226
ENSG00000125450 E048 30.2620455 0.0062307755 0.94141683 0.98350396 17 75231828 75231979 152 + 1.497 1.492 -0.017
ENSG00000125450 E049 1.1063072 0.0113869382 0.80314020 0.92687473 17 75231980 75232116 137 + 0.302 0.341 0.246
ENSG00000125450 E050 21.9751008 0.0006375379 0.63984891 0.84691066 17 75232851 75232919 69 + 1.345 1.374 0.102
ENSG00000125450 E051 20.6093327 0.0043088635 0.79144431 0.92014711 17 75232920 75232968 49 + 1.324 1.342 0.062
ENSG00000125450 E052 2.2296098 0.0062856710 0.19385526 0.47370218 17 75232969 75233057 89 + 0.399 0.587 0.924
ENSG00000125450 E053 24.5641229 0.0059434118 0.57145119 0.80765515 17 75233058 75233124 67 + 1.387 1.423 0.127
ENSG00000125450 E054 18.2005130 0.0009544249 0.32285961 0.61568569 17 75233125 75233158 34 + 1.245 1.313 0.238
ENSG00000125450 E055 15.2009793 0.0017393575 0.01317267 0.09616331 17 75234637 75234666 30 + 1.099 1.287 0.668
ENSG00000125450 E056 12.1739866 0.0098139325 0.46240007 0.73279726 17 75234667 75234703 37 + 1.081 1.150 0.246
ENSG00000125450 E057 15.3974952 0.0011760134 0.16300915 0.43164451 17 75234704 75234752 49 + 1.156 1.259 0.366
ENSG00000125450 E058 15.5367090 0.0010358138 0.45690163 0.72901697 17 75234753 75234788 36 + 1.245 1.192 -0.189
ENSG00000125450 E059 2.1327711 0.2106027576 0.07510773 0.27969760 17 75234789 75234794 6 + 0.244 0.637 2.147
ENSG00000125450 E060 7.8005290 0.0045881393 0.03177081 0.16843871 17 75234795 75235099 305 + 0.815 1.032 0.823
ENSG00000125450 E061 11.5052956 0.0011759936 0.64238719 0.84831676 17 75235100 75235112 13 + 1.116 1.078 -0.137
ENSG00000125450 E062 9.2643527 0.0014355134 0.16934142 0.44111376 17 75235113 75235115 3 + 1.072 0.948 -0.457
ENSG00000125450 E063 19.0827275 0.0007727809 0.32860846 0.62110828 17 75235116 75235201 86 + 1.335 1.271 -0.224
ENSG00000125450 E064 2.6070150 0.0128679423 0.16746649 0.43808334 17 75235202 75235421 220 + 0.441 0.637 0.924
ENSG00000125450 E065 1.2276211 0.0128271303 0.93307645 0.98066031 17 75235422 75235480 59 + 0.353 0.341 -0.076
ENSG00000125450 E066 15.2515412 0.0009426331 0.14374254 0.40371870 17 75235578 75235856 279 + 1.263 1.157 -0.377

Help

Please Click HERE to learn more details about the results from DEXseq.