ENSG00000125733

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000313285 ENSG00000125733 No_inf pgKDN_inf TRIP10 protein_coding protein_coding 29.17551 30.96843 26.33726 1.515957 1.655369 -0.2336111 16.583206 11.469728 18.887789 0.9063221 1.2908945 0.719129 0.5779417 0.374250 0.716925 0.342675 0.0001960278 0.0001960278 FALSE TRUE
ENST00000598843 ENSG00000125733 No_inf pgKDN_inf TRIP10 protein_coding retained_intron 29.17551 30.96843 26.33726 1.515957 1.655369 -0.2336111 5.886642 9.985971 4.263551 1.2991379 1.1715557 -1.225911 0.1972083 0.319925 0.158400 -0.161525 0.2839962828 0.0001960278   FALSE
MSTRG.14402.6 ENSG00000125733 No_inf pgKDN_inf TRIP10 protein_coding   29.17551 30.96843 26.33726 1.515957 1.655369 -0.2336111 3.265533 5.231971 1.339420 0.7173149 0.2551674 -1.957770 0.1092417 0.168875 0.052625 -0.116250 0.0990681714 0.0001960278 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000125733 E001 0.0000000       19 6737925 6738270 346 +      
ENSG00000125733 E002 0.0000000       19 6739032 6739288 257 +      
ENSG00000125733 E003 0.2438580 0.0160971385 9.390454e-01   19 6739680 6739713 34 + 0.099 0.091 -0.124
ENSG00000125733 E004 0.8523195 0.0134894798 6.141755e-01 0.8322888511 19 6739714 6739726 13 + 0.306 0.231 -0.539
ENSG00000125733 E005 1.9583398 0.0086224351 8.436786e-01 0.9441474766 19 6739727 6739738 12 + 0.483 0.459 -0.124
ENSG00000125733 E006 3.7550471 0.0039839149 5.928076e-02 0.2443386005 19 6739739 6739761 23 + 0.786 0.554 -0.986
ENSG00000125733 E007 6.3066755 0.0021661238 2.139067e-02 0.1324679684 19 6739762 6739785 24 + 0.975 0.737 -0.920
ENSG00000125733 E008 0.6064155 0.0157686859 5.810151e-01 0.8132919323 19 6740683 6740908 226 + 0.247 0.167 -0.709
ENSG00000125733 E009 0.1186381 0.0119594340 4.864392e-01   19 6740909 6740917 9 + 0.099 0.000 -9.283
ENSG00000125733 E010 0.2459004 0.0162303529 9.382014e-01   19 6740918 6740943 26 + 0.099 0.091 -0.124
ENSG00000125733 E011 0.9988354 0.0238303088 1.998413e-01 0.4816659602 19 6740944 6741009 66 + 0.179 0.381 1.461
ENSG00000125733 E012 15.1246496 0.0009649056 6.732003e-02 0.2616632030 19 6741010 6741125 116 + 1.270 1.143 -0.451
ENSG00000125733 E013 0.6270271 0.0148745201 2.098228e-01 0.4942386828 19 6741126 6741224 99 + 0.099 0.287 1.876
ENSG00000125733 E014 13.4276136 0.0033677812 2.101357e-01 0.4945802872 19 6741225 6741281 57 + 1.206 1.113 -0.334
ENSG00000125733 E015 22.8788036 0.0010841845 2.918202e-01 0.5852029204 19 6742967 6743114 148 + 1.407 1.349 -0.201
ENSG00000125733 E016 14.5815504 0.0010071377 7.910458e-01 0.9199377372 19 6743194 6743256 63 + 1.199 1.185 -0.051
ENSG00000125733 E017 0.6271531 0.0148978315 2.097641e-01 0.4942083596 19 6743257 6743369 113 + 0.099 0.287 1.876
ENSG00000125733 E018 0.6265540 0.1999578014 2.794561e-01 0.5727510095 19 6743370 6743493 124 + 0.099 0.287 1.877
ENSG00000125733 E019 21.5594771 0.0006360076 6.060784e-01 0.8284730393 19 6743494 6743598 105 + 1.366 1.340 -0.091
ENSG00000125733 E020 21.2942230 0.0007027587 2.008282e-01 0.4829217282 19 6743708 6743836 129 + 1.299 1.384 0.296
ENSG00000125733 E021 0.1186381 0.0119594340 4.864392e-01   19 6743837 6743890 54 + 0.099 0.000 -9.283
ENSG00000125733 E022 22.2153159 0.0045123792 8.862971e-01 0.9619587041 19 6744554 6744700 147 + 1.356 1.371 0.052
ENSG00000125733 E023 27.5635654 0.0005335547 1.569630e-02 0.1084100222 19 6744800 6744994 195 + 1.518 1.392 -0.432
ENSG00000125733 E024 2.0039703 0.0071195257 1.719794e-02 0.1147394780 19 6744995 6745200 206 + 0.247 0.607 1.992
ENSG00000125733 E025 12.2946918 0.0222200057 1.751439e-07 0.0000096587 19 6745635 6746028 394 + 0.728 1.301 2.128
ENSG00000125733 E026 2.8812792 0.0138820153 3.273970e-03 0.0369024627 19 6746029 6746177 149 + 0.306 0.737 2.124
ENSG00000125733 E027 1.3873924 0.0093346865 6.172257e-03 0.0576141458 19 6746178 6746196 19 + 0.099 0.524 3.198
ENSG00000125733 E028 5.6148979 0.0029013183 1.534160e-03 0.0208211881 19 6746308 6746432 125 + 0.581 0.953 1.504
ENSG00000125733 E029 4.2163070 0.0171169099 8.857777e-02 0.3086743793 19 6746433 6746451 19 + 0.581 0.806 0.940
ENSG00000125733 E030 20.9268741 0.0007009348 4.621688e-01 0.7326760340 19 6746452 6746561 110 + 1.361 1.321 -0.141
ENSG00000125733 E031 20.7167922 0.0006948093 7.923515e-01 0.9207283348 19 6749934 6750066 133 + 1.341 1.330 -0.039
ENSG00000125733 E032 25.8566644 0.0068519879 8.412749e-01 0.9430542838 19 6750292 6750431 140 + 1.432 1.424 -0.028
ENSG00000125733 E033 0.0000000       19 6750432 6750511 80 +      
ENSG00000125733 E034 17.8569794 0.0009168259 3.459924e-01 0.6369074935 19 6750512 6750633 122 + 1.305 1.247 -0.203
ENSG00000125733 E035 0.2435110 0.0161614263 9.397967e-01   19 6751034 6751062 29 + 0.099 0.091 -0.124
ENSG00000125733 E036 30.7832232 0.0004871991 9.671022e-01 0.9933726595 19 6751063 6751530 468 + 1.497 1.504 0.026

Help

Please Click HERE to learn more details about the results from DEXseq.