ENSG00000125734

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264080 ENSG00000125734 No_inf pgKDN_inf GPR108 protein_coding protein_coding 72.08798 73.59561 64.22759 3.250937 1.224247 -0.1963979 33.095046 24.380315 39.685127 4.0971327 1.1579409 0.7026535 0.46955000 0.340675 0.618500 0.277825 0.02355890 0.01452827 FALSE TRUE
ENST00000537722 ENSG00000125734 No_inf pgKDN_inf GPR108 protein_coding protein_coding_CDS_not_defined 72.08798 73.59561 64.22759 3.250937 1.224247 -0.1963979 9.318238 9.381792 4.458731 3.1970428 4.4587313 -1.0715351 0.12780000 0.133025 0.068175 -0.064850 0.44353731 0.01452827 FALSE TRUE
ENST00000594034 ENSG00000125734 No_inf pgKDN_inf GPR108 protein_coding protein_coding 72.08798 73.59561 64.22759 3.250937 1.224247 -0.1963979 1.175828 0.000000 3.527484 0.0000000 3.5274838 8.4665797 0.01930000 0.000000 0.057900 0.057900 0.83878644 0.01452827 FALSE TRUE
ENST00000597706 ENSG00000125734 No_inf pgKDN_inf GPR108 protein_coding nonsense_mediated_decay 72.08798 73.59561 64.22759 3.250937 1.224247 -0.1963979 4.390751 7.434910 0.000000 4.3473960 0.0000000 -9.5401106 0.05625833 0.096725 0.000000 -0.096725 0.49816365 0.01452827 TRUE TRUE
ENST00000598626 ENSG00000125734 No_inf pgKDN_inf GPR108 protein_coding protein_coding_CDS_not_defined 72.08798 73.59561 64.22759 3.250937 1.224247 -0.1963979 9.407436 11.609274 9.614938 5.0017842 4.0856624 -0.2716708 0.13028333 0.154275 0.147275 -0.007000 1.00000000 0.01452827 FALSE FALSE
ENST00000598955 ENSG00000125734 No_inf pgKDN_inf GPR108 protein_coding protein_coding 72.08798 73.59561 64.22759 3.250937 1.224247 -0.1963979 3.004789 6.405518 0.000000 2.2578196 0.0000000 -9.3254219 0.03904167 0.083525 0.000000 -0.083525 0.01452827 0.01452827 FALSE FALSE
ENST00000600773 ENSG00000125734 No_inf pgKDN_inf GPR108 protein_coding retained_intron 72.08798 73.59561 64.22759 3.250937 1.224247 -0.1963979 4.215671 5.686511 1.885741 0.8523773 0.6809647 -1.5873168 0.05700833 0.076900 0.029925 -0.046975 0.30353617 0.01452827 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000125734 E001 0.2539903 0.0160631800 0.2657446000   19 6729914 6730054 141 - 0.000 0.169 10.187
ENSG00000125734 E002 0.2539903 0.0160631800 0.2657446000   19 6730055 6730055 1 - 0.000 0.169 10.192
ENSG00000125734 E003 0.8642423 0.2095790730 0.8319554245 0.93927831 19 6730056 6730067 12 - 0.245 0.290 0.323
ENSG00000125734 E004 4.1868299 0.0290828396 0.6461963548 0.85024738 19 6730068 6730084 17 - 0.680 0.741 0.249
ENSG00000125734 E005 4.3140922 0.0431507336 0.5650915989 0.80405356 19 6730085 6730085 1 - 0.680 0.759 0.323
ENSG00000125734 E006 8.5394551 0.0172032902 0.0708039529 0.26943058 19 6730086 6730097 12 - 0.864 1.058 0.724
ENSG00000125734 E007 43.7106008 0.0003599527 0.4416898402 0.71716590 19 6730098 6730242 145 - 1.630 1.665 0.120
ENSG00000125734 E008 67.4215919 0.0002783187 0.1749461542 0.44879880 19 6730243 6730384 142 - 1.859 1.811 -0.160
ENSG00000125734 E009 37.3589033 0.0085404432 0.1199667782 0.36611148 19 6730987 6731054 68 - 1.630 1.537 -0.318
ENSG00000125734 E010 26.2268739 0.0066747182 0.9525281182 0.98825170 19 6731055 6731111 57 - 1.436 1.433 -0.010
ENSG00000125734 E011 25.9580730 0.0005472875 0.2114661688 0.49643744 19 6731199 6731234 36 - 1.389 1.462 0.252
ENSG00000125734 E012 23.5704947 0.0048778500 0.0281531694 0.15684465 19 6731235 6731252 18 - 1.305 1.451 0.506
ENSG00000125734 E013 25.6890985 0.0005743112 0.3987285923 0.68261262 19 6731253 6731282 30 - 1.398 1.448 0.171
ENSG00000125734 E014 31.5702860 0.0004949981 0.4304964570 0.70835304 19 6731473 6731522 50 - 1.489 1.531 0.145
ENSG00000125734 E015 30.0963343 0.0136722413 0.5659390787 0.80451656 19 6731891 6731934 44 - 1.467 1.512 0.156
ENSG00000125734 E016 32.8289124 0.0153008889 0.3978253595 0.68187973 19 6732025 6732082 58 - 1.492 1.557 0.222
ENSG00000125734 E017 39.7431666 0.0003687310 0.1096742775 0.34755570 19 6732083 6732155 73 - 1.567 1.643 0.258
ENSG00000125734 E018 48.2519966 0.0016168957 0.4656037900 0.73457314 19 6732263 6732380 118 - 1.708 1.676 -0.106
ENSG00000125734 E019 0.0000000       19 6732472 6732475 4 -      
ENSG00000125734 E020 33.6690691 0.0004569577 0.4658716654 0.73477373 19 6732476 6732549 74 - 1.558 1.522 -0.123
ENSG00000125734 E021 5.1355885 0.0029192381 0.0001442028 0.00320059 19 6732550 6732773 224 - 0.480 0.946 1.953
ENSG00000125734 E022 30.5231525 0.0004676993 0.9411157176 0.98341173 19 6732987 6733062 76 - 1.499 1.496 -0.010
ENSG00000125734 E023 20.4688483 0.0008399647 0.9702084930 0.99397974 19 6733168 6733189 22 - 1.332 1.330 -0.005
ENSG00000125734 E024 29.5212351 0.0004989543 0.1511895003 0.41442643 19 6733190 6733233 44 - 1.440 1.519 0.271
ENSG00000125734 E025 36.3762915 0.0004029617 0.0075897409 0.06664687 19 6733234 6733301 68 - 1.496 1.628 0.453
ENSG00000125734 E026 39.4005165 0.0003471690 0.6325339555 0.84261790 19 6733570 6733674 105 - 1.593 1.616 0.079
ENSG00000125734 E027 30.4641021 0.0004930110 0.3337767714 0.62576183 19 6733845 6733913 69 - 1.523 1.473 -0.173
ENSG00000125734 E028 2.2044652 0.0100811592 0.8900414205 0.96327959 19 6733935 6734004 70 - 0.515 0.496 -0.092
ENSG00000125734 E029 26.7112176 0.0007326974 0.0416733339 0.19849948 19 6734005 6734054 50 - 1.499 1.384 -0.396
ENSG00000125734 E030 40.3171839 0.0003943870 0.0865505353 0.30489021 19 6734183 6734307 125 - 1.655 1.577 -0.267
ENSG00000125734 E031 0.9972946 0.2647974452 0.2972959339 0.59046675 19 6735374 6735539 166 - 0.178 0.384 1.492
ENSG00000125734 E032 1.1314184 0.1047222066 0.0327126592 0.17147678 19 6735540 6735621 82 - 0.098 0.462 2.908
ENSG00000125734 E033 35.2075270 0.0004089305 0.1639878097 0.43313019 19 6735622 6735704 83 - 1.593 1.525 -0.232
ENSG00000125734 E034 23.6824625 0.0007104016 0.0590057499 0.24371390 19 6735908 6735958 51 - 1.448 1.335 -0.390
ENSG00000125734 E035 24.9665880 0.0079943159 0.0135910646 0.09812250 19 6736592 6736711 120 - 1.496 1.325 -0.590
ENSG00000125734 E036 0.8713870 0.0959654033 0.3328221306 0.62491575 19 6736712 6736989 278 - 0.178 0.340 1.230
ENSG00000125734 E037 1.8435124 0.0088364463 0.8966896440 0.96596309 19 6736990 6737267 278 - 0.442 0.462 0.101
ENSG00000125734 E038 0.4890031 0.0157967528 0.9473766083   19 6737268 6737456 189 - 0.178 0.169 -0.092
ENSG00000125734 E039 13.8430448 0.0010851464 0.0055266859 0.05322791 19 6737457 6737580 124 - 1.272 1.058 -0.761

Help

Please Click HERE to learn more details about the results from DEXseq.