ENSG00000125779

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000336066 ENSG00000125779 No_inf pgKDN_inf PANK2 protein_coding nonsense_mediated_decay 9.11342 11.70124 8.341255 1.8878 1.205407 -0.4878284 2.1261283 2.123589 2.2548004 0.7126746 0.7641650 0.08610145 0.27354167 0.219625 0.296900 0.077275 0.86950590 0.02610859 TRUE FALSE
ENST00000464452 ENSG00000125779 No_inf pgKDN_inf PANK2 protein_coding protein_coding_CDS_not_defined 9.11342 11.70124 8.341255 1.8878 1.205407 -0.4878284 1.2894175 1.864064 1.7159639 0.8149843 1.3339413 -0.11876799 0.13376667 0.188500 0.179975 -0.008525 0.92254552 0.02610859   FALSE
ENST00000471830 ENSG00000125779 No_inf pgKDN_inf PANK2 protein_coding protein_coding_CDS_not_defined 9.11342 11.70124 8.341255 1.8878 1.205407 -0.4878284 0.4563503 0.000000 1.1700103 0.0000000 0.5226684 6.88265562 0.05361667 0.000000 0.136425 0.136425 0.04883385 0.02610859   FALSE
ENST00000495692 ENSG00000125779 No_inf pgKDN_inf PANK2 protein_coding protein_coding 9.11342 11.70124 8.341255 1.8878 1.205407 -0.4878284 1.3848550 1.332268 0.8482344 0.7862508 0.8482344 -0.64522948 0.15970000 0.094875 0.096925 0.002050 0.84036136 0.02610859 TRUE FALSE
ENST00000610179 ENSG00000125779 No_inf pgKDN_inf PANK2 protein_coding protein_coding 9.11342 11.70124 8.341255 1.8878 1.205407 -0.4878284 1.1557913 1.939883 0.7130834 0.1119277 0.1603878 -1.43115365 0.12699167 0.179250 0.084975 -0.094275 0.55521032 0.02610859 FALSE TRUE
ENST00000619433 ENSG00000125779 No_inf pgKDN_inf PANK2 protein_coding protein_coding_CDS_not_defined 9.11342 11.70124 8.341255 1.8878 1.205407 -0.4878284 0.7898722 2.369617 0.0000000 2.3696166 0.0000000 -7.89458532 0.04700000 0.141000 0.000000 -0.141000 0.87543187 0.02610859   FALSE
ENST00000621507 ENSG00000125779 No_inf pgKDN_inf PANK2 protein_coding protein_coding 9.11342 11.70124 8.341255 1.8878 1.205407 -0.4878284 0.8045385 0.000000 1.5631105 0.0000000 0.5269612 7.29747617 0.09727500 0.000000 0.194950 0.194950 0.02610859 0.02610859 FALSE TRUE
ENST00000621891 ENSG00000125779 No_inf pgKDN_inf PANK2 protein_coding protein_coding_CDS_not_defined 9.11342 11.70124 8.341255 1.8878 1.205407 -0.4878284 0.8568992 1.808199 0.0000000 1.1226678 0.0000000 -7.50636638 0.08265000 0.161100 0.000000 -0.161100 0.57175891 0.02610859   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000125779 E001 0.0000000       20 3888839 3888904 66 +      
ENSG00000125779 E002 0.0000000       20 3888923 3888933 11 +      
ENSG00000125779 E003 0.0000000       20 3888934 3889016 83 +      
ENSG00000125779 E004 0.0000000       20 3889017 3889386 370 +      
ENSG00000125779 E005 0.0000000       20 3889387 3889388 2 +      
ENSG00000125779 E006 4.1448906 0.0036231068 0.24350656 0.533504599 20 3889389 3889669 281 + 0.785 0.638 -0.608
ENSG00000125779 E007 3.6526261 0.0070003218 0.24267096 0.532300947 20 3889670 3889728 59 + 0.745 0.591 -0.654
ENSG00000125779 E008 0.0000000       20 3889816 3889919 104 +      
ENSG00000125779 E009 0.1265070 0.0126154910 0.63312337   20 3889920 3889932 13 + 0.000 0.087 9.358
ENSG00000125779 E010 0.1176306 0.0118985745 0.45574076   20 3891240 3891243 4 + 0.103 0.000 -9.997
ENSG00000125779 E011 0.4702767 0.0157730267 0.03037354   20 3891244 3891411 168 + 0.317 0.000 -11.997
ENSG00000125779 E012 0.0000000       20 3901548 3901551 4 +      
ENSG00000125779 E013 0.0000000       20 3901552 3901617 66 +      
ENSG00000125779 E014 8.3140922 0.0022781537 0.34793495 0.638477588 20 3907926 3908135 210 + 1.017 0.922 -0.352
ENSG00000125779 E015 4.7535635 0.1169730361 0.23093430 0.519382351 20 3908136 3908278 143 + 0.856 0.660 -0.792
ENSG00000125779 E016 0.7366678 0.0156101649 0.84137704 0.943054284 20 3908690 3908905 216 + 0.257 0.223 -0.267
ENSG00000125779 E017 13.3145032 0.0099609132 0.15157932 0.414925609 20 3910577 3910830 254 + 1.219 1.093 -0.452
ENSG00000125779 E018 10.8266546 0.0013964946 0.74949677 0.901321294 20 3912458 3912634 177 + 1.060 1.077 0.063
ENSG00000125779 E019 9.1235751 0.0017455602 0.33150601 0.623639980 20 3916927 3917050 124 + 0.957 1.034 0.286
ENSG00000125779 E020 11.0325983 0.0013974812 0.71708301 0.886081645 20 3918671 3918796 126 + 1.098 1.060 -0.138
ENSG00000125779 E021 18.4772775 0.0008580352 0.28786369 0.581354019 20 3923244 3924817 1574 + 1.253 1.310 0.199
ENSG00000125779 E022 0.8443183 0.0143198500 0.17690897 0.451282117 20 3924818 3924881 64 + 0.370 0.160 -1.589
ENSG00000125779 E023 12.6818148 0.0016528668 0.00013999 0.003127681 20 3924882 3929221 4340 + 0.944 1.238 1.065
ENSG00000125779 E024 0.0000000       20 3929222 3929673 452 +      
ENSG00000125779 E025 0.0000000       20 3929674 3929887 214 +      

Help

Please Click HERE to learn more details about the results from DEXseq.