ENSG00000125826

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000356286 ENSG00000125826 No_inf pgKDN_inf RBCK1 protein_coding protein_coding 60.68711 76.03013 47.19845 0.9872286 2.449752 -0.687716 12.749238 14.645989 13.138682 0.7507044 0.9968133 -0.1565721 0.21876667 0.193025 0.283025 0.090000 0.49322196 0.01952633 FALSE TRUE
ENST00000400245 ENSG00000125826 No_inf pgKDN_inf RBCK1 protein_coding protein_coding 60.68711 76.03013 47.19845 0.9872286 2.449752 -0.687716 5.525845 4.297455 2.657642 2.0792518 1.5396749 -0.6912707 0.09445000 0.056250 0.058575 0.002325 0.90809244 0.01952633 FALSE TRUE
ENST00000400247 ENSG00000125826 No_inf pgKDN_inf RBCK1 protein_coding protein_coding 60.68711 76.03013 47.19845 0.9872286 2.449752 -0.687716 4.340862 3.984703 6.651042 0.5295779 2.1792214 0.7376596 0.07538333 0.052275 0.135525 0.083250 0.30975922 0.01952633 TRUE FALSE
ENST00000475269 ENSG00000125826 No_inf pgKDN_inf RBCK1 protein_coding protein_coding 60.68711 76.03013 47.19845 0.9872286 2.449752 -0.687716 11.550619 10.792493 12.248640 2.1289340 1.0361623 0.1824347 0.19895833 0.142275 0.262025 0.119750 0.28405285 0.01952633 FALSE TRUE
MSTRG.17894.1 ENSG00000125826 No_inf pgKDN_inf RBCK1 protein_coding   60.68711 76.03013 47.19845 0.9872286 2.449752 -0.687716 9.616618 16.199903 3.880941 1.0672043 0.7950656 -2.0586843 0.14775000 0.212950 0.080650 -0.132300 0.01952633 0.01952633 FALSE TRUE
MSTRG.17894.18 ENSG00000125826 No_inf pgKDN_inf RBCK1 protein_coding   60.68711 76.03013 47.19845 0.9872286 2.449752 -0.687716 5.163450 9.097063 2.426084 0.6799977 0.1815763 -1.9024220 0.07977500 0.120000 0.051800 -0.068200 0.14539934 0.01952633 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000125826 E001 0.0000000       20 407498 407539 42 +      
ENSG00000125826 E002 0.0000000       20 407540 407671 132 +      
ENSG00000125826 E003 0.0000000       20 408050 408052 3 +      
ENSG00000125826 E004 0.0000000       20 408053 408057 5 +      
ENSG00000125826 E005 0.9802998 1.214976e-02 3.734951e-01 6.612206e-01 20 408058 408077 20 + 0.371 0.233 -0.925
ENSG00000125826 E006 1.8127933 7.187666e-02 2.486529e-02 1.449545e-01 20 408078 408146 69 + 0.641 0.276 -1.925
ENSG00000125826 E007 1.9213642 4.618958e-02 2.380069e-03 2.903566e-02 20 408147 408170 24 + 0.703 0.233 -2.510
ENSG00000125826 E008 6.0194352 7.160110e-02 2.919004e-01 5.852549e-01 20 408171 408250 80 + 0.925 0.763 -0.629
ENSG00000125826 E009 6.0582010 2.345843e-03 7.431312e-01 8.983949e-01 20 408251 408298 48 + 0.850 0.813 -0.141
ENSG00000125826 E010 3.7069027 3.856703e-03 8.036510e-01 9.270889e-01 20 408299 408304 6 + 0.673 0.641 -0.137
ENSG00000125826 E011 4.4405169 4.952993e-03 5.868209e-01 8.168562e-01 20 408305 408312 8 + 0.758 0.691 -0.273
ENSG00000125826 E012 9.0171023 1.627523e-03 4.934443e-01 7.553764e-01 20 408313 408342 30 + 1.019 0.954 -0.241
ENSG00000125826 E013 41.7102880 5.729754e-04 4.817015e-02 2.160147e-01 20 408343 408503 161 + 1.665 1.571 -0.319
ENSG00000125826 E014 17.6273428 6.476022e-03 1.225210e-01 3.704479e-01 20 408504 408511 8 + 1.320 1.202 -0.415
ENSG00000125826 E015 50.4459415 2.507152e-03 3.691059e-04 6.865603e-03 20 408512 408690 179 + 1.788 1.624 -0.557
ENSG00000125826 E016 32.6382818 1.244103e-03 2.226418e-05 6.746046e-04 20 408691 408779 89 + 1.638 1.413 -0.773
ENSG00000125826 E017 2.2181579 3.246912e-02 7.115935e-01 8.834761e-01 20 409830 409880 51 + 0.526 0.470 -0.273
ENSG00000125826 E018 13.5196651 2.041616e-03 3.216921e-02 1.697002e-01 20 409881 409883 3 + 1.244 1.073 -0.609
ENSG00000125826 E019 49.0716983 3.059094e-04 1.220522e-02 9.153130e-02 20 409884 410025 142 + 1.743 1.634 -0.367
ENSG00000125826 E020 29.7364414 5.477144e-04 6.110881e-08 3.732551e-06 20 410412 410764 353 + 1.635 1.342 -1.008
ENSG00000125826 E021 1.7509912 7.826081e-03 2.901287e-01 5.837643e-01 20 417220 417342 123 + 0.304 0.470 0.949
ENSG00000125826 E022 32.1951225 9.659561e-04 8.628743e-01 9.525989e-01 20 417526 417619 94 + 1.501 1.492 -0.032
ENSG00000125826 E023 49.6288046 2.397828e-03 5.170151e-01 7.725980e-01 20 417732 417930 199 + 1.698 1.667 -0.105
ENSG00000125826 E024 22.1178245 6.263072e-04 3.276549e-01 6.202133e-01 20 419347 419468 122 + 1.379 1.316 -0.218
ENSG00000125826 E025 34.5694365 9.087912e-04 1.245886e-01 3.741698e-01 20 419558 419731 174 + 1.577 1.497 -0.276
ENSG00000125826 E026 9.5143057 1.472819e-03 4.912570e-03 4.895686e-02 20 419862 419917 56 + 0.782 1.073 1.099
ENSG00000125826 E027 54.7070103 3.014112e-04 2.133022e-17 4.529229e-15 20 419918 420673 756 + 1.403 1.817 1.413
ENSG00000125826 E028 3.6528479 4.645410e-03 2.869865e-03 3.340887e-02 20 420726 420870 145 + 0.304 0.750 2.190
ENSG00000125826 E029 25.8450395 7.146466e-03 2.694854e-02 1.525603e-01 20 420871 421006 136 + 1.496 1.349 -0.510
ENSG00000125826 E030 13.1968747 1.092184e-03 2.226757e-01 5.099915e-01 20 421007 421031 25 + 1.190 1.092 -0.352
ENSG00000125826 E031 10.1381741 2.471820e-02 2.529279e-02 1.463357e-01 20 421032 421186 155 + 0.828 1.092 0.987
ENSG00000125826 E032 15.0635809 1.359726e-02 6.162532e-05 1.576708e-03 20 421187 421373 187 + 0.870 1.277 1.485
ENSG00000125826 E033 37.1898686 3.277078e-03 5.989579e-08 3.675107e-06 20 421374 422126 753 + 1.306 1.640 1.149
ENSG00000125826 E034 37.2751485 8.190367e-04 8.842731e-01 9.610847e-01 20 422127 422238 112 + 1.561 1.554 -0.025
ENSG00000125826 E035 4.3283003 3.509182e-03 7.446323e-01 8.987986e-01 20 424273 426371 2099 + 0.731 0.691 -0.166
ENSG00000125826 E036 0.0000000       20 426860 426869 10 +      
ENSG00000125826 E037 1.2340430 1.065237e-02 7.196465e-01 8.869813e-01 20 426870 427312 443 + 0.371 0.315 -0.340
ENSG00000125826 E038 69.1946450 2.653156e-04 7.675985e-01 9.100625e-01 20 427313 427492 180 + 1.827 1.816 -0.036
ENSG00000125826 E039 1.3699302 2.947488e-01 8.371778e-01 9.416635e-01 20 427493 427926 434 + 0.304 0.384 0.489
ENSG00000125826 E040 0.6158846 2.293715e-02 8.002882e-01 9.252662e-01 20 427927 428058 132 + 0.224 0.185 -0.340
ENSG00000125826 E041 1.0080587 1.167504e-02 1.628977e-01 4.314554e-01 20 428059 428490 432 + 0.126 0.351 1.882
ENSG00000125826 E042 51.3029811 3.382336e-04 7.738844e-01 9.130552e-01 20 428491 428589 99 + 1.683 1.696 0.043
ENSG00000125826 E043 10.7946365 5.984484e-03 3.006693e-04 5.816463e-03 20 428590 428898 309 + 0.758 1.140 1.437
ENSG00000125826 E044 3.8889272 1.783476e-02 3.014570e-02 1.633598e-01 20 428899 428950 52 + 0.429 0.750 1.453
ENSG00000125826 E045 22.9673976 6.125281e-04 2.293621e-01 5.180435e-01 20 428951 428962 12 + 1.403 1.327 -0.262
ENSG00000125826 E046 54.8713208 1.047734e-03 9.779733e-01 9.968441e-01 20 428963 429094 132 + 1.721 1.720 -0.003
ENSG00000125826 E047 5.8669670 2.473975e-03 1.023157e-01 3.343226e-01 20 429095 430349 1255 + 0.673 0.869 0.785
ENSG00000125826 E048 191.4969134 9.502277e-05 1.026554e-03 1.529875e-02 20 430350 432139 1790 + 2.208 2.280 0.238

Help

Please Click HERE to learn more details about the results from DEXseq.