ENSG00000125944

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000374612 ENSG00000125944 No_inf pgKDN_inf HNRNPR protein_coding protein_coding 49.43323 38.91223 58.58485 1.04976 1.900251 0.5901797 22.522352 17.524575 21.76178 4.363672 3.5790210 0.3122569 0.4647917 0.458250 0.377225 -0.081025 0.857070951 0.008510307 FALSE TRUE
ENST00000374616 ENSG00000125944 No_inf pgKDN_inf HNRNPR protein_coding protein_coding 49.43323 38.91223 58.58485 1.04976 1.900251 0.5901797 5.818320 2.811431 11.20501 1.635284 4.0545841 1.9909325 0.1075833 0.070100 0.186150 0.116050 0.776497192 0.008510307 FALSE TRUE
ENST00000476660 ENSG00000125944 No_inf pgKDN_inf HNRNPR protein_coding protein_coding_CDS_not_defined 49.43323 38.91223 58.58485 1.04976 1.900251 0.5901797 1.667821 5.003464 0.00000 1.868084 0.0000000 -8.9696640 0.0418250 0.125475 0.000000 -0.125475 0.008510307 0.008510307 FALSE TRUE
MSTRG.409.9 ENSG00000125944 No_inf pgKDN_inf HNRNPR protein_coding   49.43323 38.91223 58.58485 1.04976 1.900251 0.5901797 17.177644 12.683375 21.72931 3.121107 0.5232161 0.7762304 0.3437583 0.323100 0.372025 0.048925 0.841726118 0.008510307 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000125944 E001 0.2454921 0.0164226308 0.817899454   1 23303771 23303962 192 - 0.083 0.109 0.428
ENSG00000125944 E002 0.4983826 0.0306080923 0.200540058   1 23303963 23304106 144 - 0.083 0.268 2.014
ENSG00000125944 E003 6.4410828 0.0137222560 0.683098375 0.86869102 1 23304688 23306411 1724 - 0.889 0.843 -0.179
ENSG00000125944 E004 0.7434668 0.0132347417 0.240268377 0.52946413 1 23306412 23306503 92 - 0.153 0.330 1.428
ENSG00000125944 E005 12.6810816 0.0010395261 0.744075467 0.89873493 1 23306504 23309782 3279 - 1.122 1.148 0.094
ENSG00000125944 E006 0.7533168 0.0133101472 0.042536674 0.20100920 1 23309783 23309783 1 - 0.083 0.384 2.750
ENSG00000125944 E007 0.8709474 0.0124423047 0.127431781 0.37852136 1 23309784 23309785 2 - 0.153 0.384 1.750
ENSG00000125944 E008 26.7573405 0.0005462719 0.001048501 0.01554849 1 23309786 23309929 144 - 1.348 1.534 0.641
ENSG00000125944 E009 158.5963151 0.0001194943 0.008481298 0.07188910 1 23309930 23310332 403 - 2.174 2.232 0.195
ENSG00000125944 E010 74.8208775 0.0003405983 0.789277663 0.91914699 1 23310333 23310453 121 - 1.873 1.882 0.031
ENSG00000125944 E011 95.5992362 0.0001659506 0.958182414 0.98998342 1 23310454 23310827 374 - 1.983 1.982 -0.005
ENSG00000125944 E012 53.5547610 0.0002832705 0.581749944 0.81373778 1 23310828 23311066 239 - 1.744 1.722 -0.075
ENSG00000125944 E013 54.2860872 0.0011609252 0.027231538 0.15345374 1 23311201 23311322 122 - 1.697 1.789 0.311
ENSG00000125944 E014 0.0000000       1 23311662 23311893 232 -      
ENSG00000125944 E015 36.7894796 0.0016338783 0.889761525 0.96327959 1 23313553 23313598 46 - 1.572 1.579 0.025
ENSG00000125944 E016 48.0382424 0.0003191633 0.442750989 0.71800264 1 23313599 23313702 104 - 1.702 1.669 -0.111
ENSG00000125944 E017 74.3159578 0.0002303825 0.872526103 0.95648014 1 23318483 23318688 206 - 1.872 1.877 0.019
ENSG00000125944 E018 2.5464008 0.0281232276 0.699122652 0.87740503 1 23318689 23318697 9 - 0.573 0.515 -0.272
ENSG00000125944 E019 50.0448017 0.0002940404 0.900247016 0.96759511 1 23321528 23321663 136 - 1.708 1.702 -0.017
ENSG00000125944 E020 48.4673184 0.0003406638 0.119266649 0.36492352 1 23323556 23323732 177 - 1.720 1.653 -0.226
ENSG00000125944 E021 34.5726174 0.0008751041 0.048054639 0.21566896 1 23333518 23333631 114 - 1.591 1.489 -0.349
ENSG00000125944 E022 35.0209173 0.0007274376 0.015556826 0.10776239 1 23337754 23337861 108 - 1.605 1.481 -0.424
ENSG00000125944 E023 0.2452102 0.0164063855 0.818150256   1 23338063 23338163 101 - 0.083 0.109 0.428
ENSG00000125944 E024 0.1187032 0.0118581845 0.723085218   1 23338270 23338489 220 - 0.083 0.000 -8.019
ENSG00000125944 E025 25.4848313 0.0005353380 0.138476986 0.39586212 1 23338490 23338608 119 - 1.457 1.370 -0.301
ENSG00000125944 E026 8.6523570 0.0029099998 0.002198509 0.02742238 1 23340852 23341017 166 - 1.093 0.786 -1.156
ENSG00000125944 E027 0.6089622 0.0147819013 0.905475158 0.96975055 1 23341018 23341020 3 - 0.213 0.195 -0.157
ENSG00000125944 E028 0.0000000       1 23341021 23341038 18 -      
ENSG00000125944 E029 11.0829191 0.0012433478 0.004616156 0.04680067 1 23344211 23344336 126 - 1.174 0.923 -0.915

Help

Please Click HERE to learn more details about the results from DEXseq.